Triptolide in the treatment of psoriasis and other immune-mediated inflammatory diseases

Targeting the Interleukin-12/23 Cytokine Family in the Treatment of Psoriatic Disease

(2015) Neil H. Shear et al.   JOURNAL OF CUTANEOUS MEDICINE AND SURGERY

RNA polymerase – An important molecular target of triptolide in cancer cells

(2010) Jingxuan Pan   CANCER LETTERS

Triptolide Inhibits IL-12/IL-23 Expression in APCs via CCAAT/Enhancer-Binding Protein  

(2010) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Phase I dose-escalation study of F60008, a novel apoptosis inducer, in patients with advanced solid tumours

(2009) J.J.E.M. Kitzen et al.   EUROPEAN JOURNAL OF CANCER

Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA

(2009) S. Vispe et al.   MOLECULAR CANCER THERAPEUTICS

Tripterygium wilfordii Hook F Treatment for Idiopathic Refractory Nephrotic Syndrome in Adults: A Meta-Analysis

(2009) Gaosi Xu et al.   NEPHRON CLINICAL PRACTICE

Differential effects of triptolide and tetrandrine on activation of COX-2, NF-κB, and AP-1 and virus production in dengue virus-infected human lung cells

(2008) Jun-Ting Liou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

(5R)-5-hydroxytriptolide inhibits the immune response of human peripheral blood mononuclear cells

(2008) Ru Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Triptolide inhibits COX-2 expression and PGE2release by suppressing the activity of NF-κB and JNK in LPS-treated microglia

(2008) Yuntao Gong et al.   JOURNAL OF NEUROCHEMISTRY

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

(2008) Ludwig Kappos et al.   LANCET

Triptolide Inhibits the Differentiation of Th17 cells and Suppresses Collagen-induced Arthritis

(2008) Y. Wang et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation

(2008) Yan Liu et al.   TRANSPLANT INTERNATIONAL

IMMUNOCHEMICAL CHARACTERIZATION OF THE FUNCTIONAL CONSTITUENTS OFTRIPTERYGIUM WILFORDIICONTRIBUTING TO ITS ANTI-INFLAMMATORY PROPERTY

(2007) Kwong-Fai Wong et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY