Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X7 receptor antagonist: a prospective genotyping approach

Structural interpretation of P2X receptor mutagenesis studies on drug action

(2010) Richard J Evans   BRITISH JOURNAL OF PHARMACOLOGY

Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

(2010) Leanne Stokes et al.   FASEB JOURNAL

The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18

(2010) S. Jha et al.   JOURNAL OF NEUROSCIENCE

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

(2009) Calliope A Dendrou et al.   NATURE GENETICS

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

Genetics of the P2X7 receptor and human disease

(2009) Stephen J. Fuller et al.   Purinergic Signalling

The P2X7 receptor–pannexin connection to dye uptake and IL-1β release

(2009) Pablo Pelegrin et al.   Purinergic Signalling

From Human Genetics and Genomics to Pharmacogenetics and Pharmacogenomics: Past Lessons, Future Directions

(2008) Daniel W. Nebert et al.   DRUG METABOLISM REVIEWS

Selective P2X7 receptor antagonists for chronic inflammation and pain

(2008) William A. Carroll et al.   Purinergic Signalling