Acquisition of epithelial–mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells

Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2

(2015) Zhiwei Wang et al.   Oncotarget

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway

(2015) Qiong Wu et al.   Oncotarget

Establishment of Paclitaxel-resistant Breast Cancer Cell Line and Nude Mice Models, and Underlying Multidrug Resistance Mechanisms in Vitro and in Vivo

(2014) Si-Ying Chen et al.   Asian Pacific Journal of Cancer Prevention

Proteomic-based Analysis for Identification of Proteins Involved in 5-fluorouracil Resistance in Hepatocellular Carcinoma

(2014) Yi Tan et al.   CURRENT PHARMACEUTICAL DESIGN

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Epithelial-to-mesenchymal transition: What is the impact on breast cancer stem cells and drug resistance

(2013) Paraskevi Mallini et al.   CANCER TREATMENT REVIEWS

Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression

(2013) Chia-Hsin Chan et al.   CELL

New drugs, new knowledge, new targets

(2013) Mariana Chavez-MacGregor et al.   Nature Reviews Clinical Oncology

Emerging targeted agents in metastatic breast cancer

(2013) Dimitrios Zardavas et al.   Nature Reviews Clinical Oncology

Adjuvant Systemic Therapies in Breast Cancer

(2013) Leonel F. Hernandez-Aya et al.   SURGICAL CLINICS OF NORTH AMERICA

Acetylation-Dependent Regulation of Skp2 Function

(2012) Hiroyuki Inuzuka et al.   CELL

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

(2012) Chia-Hsin Chan et al.   CELL

Skp2 is a Promising Therapeutic Target in Breast Cancer

(2012) Zhiwei Wang et al.   Frontiers in Oncology

Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells

(2011) Elizabeth Rico-Bautista et al.   BMC BIOLOGY

1,2,3,4,6-Penta-O-galloyl-β-d-glucose, Quercetin, Curcumin and Lycopene Induce Cell-Cycle Arrest in MDA-MB-231 and BT474 Cells through Downregulation of Skp2 Protein

(2011) Hsiu-Chen Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis

(2010) Chia-Hsin Chan et al.   NATURE CELL BIOLOGY

Pancreatic cancer: understanding and overcoming chemoresistance

(2010) Zhiwei Wang et al.   Nature Reviews Gastroenterology & Hepatology

Correlation between Skp2 expression and nodal metastasis in Stage I and II oral squamous cell carcinomas

(2010) P Tosco et al.   ORAL DISEASES

Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway

(2009) Z. Wang et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

(2008) Q. Chen et al.   BLOOD

Dissection of the APCCdh1-Skp2 Cascade in Breast Cancer

(2008) T. Fujita et al.   CLINICAL CANCER RESEARCH

EGCG Stabilizes p27kip1in E2-Stimulated MCF-7 Cells through Down-Regulation of the Skp2 Protein

(2008) Hsiu-Chen Huang et al.   ENDOCRINOLOGY

Platelet-Derived Growth Factor-D Overexpression Contributes to Epithelial-Mesenchymal Transition of PC3 Prostate Cancer Cells

(2008) Dejuan Kong et al.   STEM CELLS