期刊
BRITISH JOURNAL OF CANCER
卷 109, 期 1, 页码 1-7出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/bjc.2013.280
关键词
Cancer chemoprevention; biomarkers; trials; development
类别
资金
- Cancer Research UK [13101] Funding Source: researchfish
- Cancer Research UK [13101] Funding Source: Medline
Cancer chemoprevention involves the chronic administration of a synthetic, natural or biological agent to reduce or delay the occurrence of malignancy. The potential value of this approach has been demonstrated with trials in breast, prostate and colon cancer. The paradigm for developing new chemopreventive agents has changed markedly in the last decade and now involves extensive preclinical mechanistic evaluation of agents before clinical trials are instituted and a focus on defining biomarkers of activity that can be used as early predictors of efficacy. This review will summarise the current status of the field of chemoprevention and highlight potential new developments.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据