Article
Medicine, General & Internal
Lingli Li, Xuefeng Kan, Yongjun Zhao, Bo Liang, Tianhe Ye, Lian Yang, Chuansheng Zheng
Summary: This study developed radiomics nomograms for predicting overall survival and time to progression in patients with advanced hepatocellular carcinoma. Apatinib plus TACE treatment benefited the patients, and the clinical-radiomics nomograms showed better performance in predicting OS and TTP compared to radiomics nomograms.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Oncology
Haidar Abdul-Muhsin, Noel De Lucia, Vijay Singh, Kassem Faraj, Kyle Rose, Stephen Cha, Nan Zhang, Nathanael Judge, Anojan Navaratnam, Mark Tyson, Thai Ho, Kenneth Jacobsohn, Erik Castle
Summary: This study aimed to predict survival outcomes for upper tract urothelial carcinoma patients following radical nephroureterectomy using simple patient data. The model showed high accuracy in predicting overall survival, cancer specific survival, and metastasis specific survival, with validation accuracy ranging from 71.4% to 78.4%.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2021)
Article
Oncology
Toshiki Kijima, Hina Yamamoto, Kazutaka Saito, Shota Kusuhara, Soichiro Yoshida, Minato Yokoyama, Yoh Matsuoka, Noboru Numao, Yasuyuki Sakai, Nobuaki Matsubara, Takeshi Yuasa, Hitoshi Masuda, Junji Yonese, Yukio Kageyama, Yasuhisa Fujii
Summary: Early C-reactive protein kinetics were found to be associated with the survival of advanced urothelial cancer patients treated with pembrolizumab, with non-responder being an independent predictor for overall survival, along with liver metastasis and poor performance status. These findings suggest that early CRP kinetics could serve as a potential biomarker for identifying patients who may benefit from immune checkpoint inhibitors.
CANCER IMMUNOLOGY IMMUNOTHERAPY
(2021)
Article
Immunology
Rong Zhao, Zhongguo Liang, Kaihua Chen, Xiaodong Zhu
Summary: This study aimed to establish and validate a nomogram based on inflammatory biomarkers and nutritional indicators to predict overall survival in locoregionally advanced nasopharyngeal carcinoma. The results showed that the nomogram had a more accurate prognostic prediction than the 8th AJCC staging system.
JOURNAL OF INFLAMMATION RESEARCH
(2022)
Article
Oncology
Laibang Luo, Xuyang Wang, Huaxiang Wang, Chengkai Yang, Youfu Zhang, Xinchang Li, Zhidan Xu
Summary: This study found that the protein level of CTSA in hepatocellular carcinoma (HCC) is strongly associated with poor clinical outcome, suggesting its potential as a diagnostic and prognostic biomarker.
AMERICAN JOURNAL OF CANCER RESEARCH
(2022)
Article
Oncology
Yating Wang, Genji Bai, Wei Huang, Hui Zhang, Wei Chen
Summary: This study developed a radiomics nomogram based on contrast-enhanced computed tomography (CECT) to predict the lymphovascular invasion (LVI) status of esophageal squamous cell carcinoma (ESCC) before surgery. The nomogram was constructed using clinical and radiomics features, and showed higher accuracy in LVI prediction.
FRONTIERS IN ONCOLOGY
(2023)
Article
Endocrinology & Metabolism
Zhengqing Song, Lisha Cheng, Lili Lu, Weiqi Lu, Yuhong Zhou, Zhiming Wang
Summary: This study aimed to develop and validate practical nomograms for predicting overall survival (OS) and cancer-specific survival (CSS) in synovial sarcoma (SyS) patients. The nomograms demonstrated higher predictive accuracy and clinical value than the AJCC staging system.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Lianzhen Zhong, Di Dong, Xueliang Fang, Fan Zhang, Ning Zhang, Liwen Zhang, Mengjie Fang, Wei Jiang, Shaobo Liang, Cong Li, Yujia Liu, Xun Zhao, Runnan Cao, Hong Shan, Zhenhua Hu, Jun Ma, Linglong Tang, Jie Tian
Summary: A deep learning-based model was developed to predict the prognosis of patients with locoregionally advanced nasopharyngeal carcinoma and recommend optimal treatment regimens. The model divided patients into ICT-preferred and CCRT-preferred groups, providing clarity in treatment decisions and personalized treatment options.
Article
Oncology
Hairong He, Tianjie Liu, Didi Han, Chengzhuo Li, Fengshuo Xu, Jun Lyu, Ye Gao
Summary: The incidence of urothelial cancer of the bladder (UCB) showed a trend of first increasing and then decreasing from 1975 to 2016, with an overall increase over that time period. Age at diagnosis, ethnic group, insurance status, marital status, differentiated grade, AJCC stage, regional lymph nodes removed status, chemotherapy status, and tumor size were found to be independent prognostic factors for postsurgery UCB. The nomogram constructed based on these factors performed well, with a C-index of 0.823 and better prediction ability for CSS than the existing AJCC system.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Huaxiang Wang, Chengkai Yang, Yi Jiang, Huanzhang Hu, Jian Fang, Fang Yang
Summary: This study constructed a gene signature to predict the recurrence rate in hepatocellular carcinoma (HCC). A total of 39 ferroptosis-related genes were identified and used to construct a risk model. The results showed that this model accurately predicts recurrence after hepatectomy, providing novel research directions for personalized treatment in HCC patients.
AMERICAN JOURNAL OF CANCER RESEARCH
(2022)
Article
Cell Biology
Xuan Zou, Yong Wei, Tao Qi, Xiaping Wang, Wenren Zuo, Tongshan Wang, Wei Zhu, Xin Zhou
Summary: In this study, higher neutrophil infiltration and lower T cell infiltration in bladder urothelial carcinoma (BUC) tumor tissues were found to be significantly correlated with worse prognosis for patients. A 6-gene prognostic model was identified, outperforming other clinical factors in risk prediction and serving as an independent prognostic factor for BUC. This model was further supported by gene set enrichment analysis and validated in additional datasets and cohorts, culminating in the creation of a comprehensive nomogram for clinical application.
Article
Oncology
Ning Xue, Guoping Ou, Weiguo Ma, Lina Jia, Jiahe Sheng, Qingxia Xu, Yubo Liu, Miaomiao Jia
Summary: The study developed and validated a predictive model for the overall survival of patients with nasopharyngeal carcinoma, and identified important features associated with patient survival. The established risk score model and nomogram provided more accurate prognostic prediction for individual patients.
CANCER CELL INTERNATIONAL
(2021)
Article
Oncology
Siwei Miao, Haike Lei, Xiaosheng Li, Wei Zhou, Guixue Wang, Anlong Sun, Ying Wang, Yongzhong Wu
Summary: A new diagnostic model has been developed to predict the overall survival of patients with nasopharyngeal carcinoma. The model takes into account demographic variables, hematological biomarkers, and oncogenic pathogens, and has been validated for its accuracy and reliability. This is important for clinical decision-making and patient counseling.
CANCER CELL INTERNATIONAL
(2022)
Article
Medicine, General & Internal
Ling Chen, Kaiming Peng, Ziyan Han, Shaobin Yu, Zhixin Huang, Hui Xu, Mingqiang Kang
Summary: This study aimed to build a nomogram to predict the risk of lymph node metastasis (LNM) in patients with pathological T1 esophageal squamous cell carcinoma (ESCC). The nomogram included smoking, carcinoembryonic antigen, vascular tumor thromboembolus, and tumor differentiation degree as independent risk factors for LNM. The nomogram showed high accuracy and can aid in clinical decision-making.
Review
Oncology
Sarah E. Fenton, David J. VanderWeele
Summary: The use of ADCs in urothelial carcinoma is expanding, with approved medications and ongoing studies. Biomarkers for treatment response prediction are not commonly used in clinical trials and practice. This review summarizes the knowledge on potential predictive biomarkers for ADCs in UC and discusses areas where biomarkers may improve patient care.
FRONTIERS IN ONCOLOGY
(2023)
Article
Urology & Nephrology
Naoko Kawamura, Minato Yokoyama, Hajime Tanaka, Takayuki Nakayama, Yosuke Yasuda, Toshiki Kijima, Soichiro Yoshida, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Kazunori Kihara, Yasuhisa Fujii
INTERNATIONAL JOURNAL OF UROLOGY
(2019)
Article
Urology & Nephrology
Yuma Waseda, Kazutaka Saito, Yudai Ishikawa, Keizo Kawano, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Shinji Morimoto, Kazunori Kihara, Yasuhisa Fujii
INTERNATIONAL JOURNAL OF UROLOGY
(2019)
Article
Urology & Nephrology
Toshiki Kijima, Hajime Tanaka, Fumitaka Koga, Hitoshi Masuda, Soichiro Yoshida, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Kazunori Kihara, Yasuhisa Fujii
Article
Radiology, Nuclear Medicine & Medical Imaging
Shugo Yajima, Soichiro Yoshida, Taro Takahara, Yuki Arita, Hiroshi Tanaka, Yuma Waseda, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Kazunori Kihara, Yasuhisa Fujii
EUROPEAN RADIOLOGY
(2019)
Editorial Material
Urology & Nephrology
Soichiro Yoshida, Takeshi Maeda, Minato Yokoyama, Masahiro Toide, Kazutaka Saito, Yasuhisa Fujii
INTERNATIONAL JOURNAL OF UROLOGY
(2019)
Editorial Material
Urology & Nephrology
Soichiro Yoshida, Maki Sugimoto, Shohei Fukuda, Naoji Taniguchi, Kazutaka Saito, Yasuhisa Fujii
INTERNATIONAL JOURNAL OF UROLOGY
(2019)
Article
Oncology
Yuma Waseda, Shuichiro Kobayashi, Eiichiro Kanda, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii
CLINICAL GENITOURINARY CANCER
(2020)
Article
Oncology
Hiroshi Fukushima, Kazutaka Saito, Yosuke Yasuda, Hajime Tanaka, Dattatraya Patil, Brittney H. Cotta, Sunil H. Patel, Viraj A. Master, Ithaar H. Derweesh, Yasuhisa Fujii
CLINICAL GENITOURINARY CANCER
(2020)
Article
Oncology
Toshiki Kijima, Hajime Tanaka, Sho Uehara, Soichiro Yoshida, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Kazunori Kihara, Yasuhisa Fujii
CLINICAL GENITOURINARY CANCER
(2020)
Article
Oncology
Soichiro Yoshida, Taro Takahara, Chikako Ishii, Yuki Arita, Yuma Waseda, Toshiki Kijima, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii
CLINICAL GENITOURINARY CANCER
(2020)
Article
Oncology
Hiroshi Fukushima, Masaharu Inoue, Toshiki Kijima, Soichiro Yoshida, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii
CLINICAL GENITOURINARY CANCER
(2020)
Article
Urology & Nephrology
Hajime Tanaka, Hiroshi Fukushima, Toshiki Kijima, Yuki Nakamura, Shugo Yajima, Sho Uehara, Soichiro Yoshida, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii
INTERNATIONAL JOURNAL OF UROLOGY
(2020)
Editorial Material
Urology & Nephrology
Toshiki Kijima, Masaya Ito, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii
INTERNATIONAL JOURNAL OF UROLOGY
(2020)
Article
Urology & Nephrology
Yuki Nakamura, Minato Yokoyama, Soichiro Yoshida, Hajime Tanaka, Toshiki Kijima, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Isao Minami, Takanobu Yoshimoto, Shotaro Naito, Yoshihiro Ogawa, Tetsuya Yamada, Shinichi Uchida, Yasuhisa Fujii
INTERNATIONAL JOURNAL OF UROLOGY
(2020)
Article
Urology & Nephrology
Hiroshi Fukushima, Shingo Moriyama, Yuma Waseda, Shohei Fukuda, Sho Uehara, Hajime Tanaka, Toshiki Kijima, Soichiro Yoshida, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii
Summary: This study investigated the role of bladder neck involvement (BNI) in risk substratification of intermediate-risk NMIBC patients and found that BNI can effectively sub-stratify patients based on their risks of progression and recurrence, assisting in determining follow-up and therapeutic strategies for these patients.
EUROPEAN UROLOGY FOCUS
(2021)
