Skeletal muscle anabolism is a side effect of therapy with the MEK inhibitor: selumetinib in patients with cholangiocarcinoma

Mitogen-activated Protein Kinase Kinase 1 (MEK1) Stabilizes MyoD through Direct Phosphorylation at Tyrosine 156 During Myogenic Differentiation

(2011) Chulman Jo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multi-Institutional Phase II Study of Selumetinib in Patients With Metastatic Biliary Cancers

(2011) Tanios Bekaii-Saab et al.   JOURNAL OF CLINICAL ONCOLOGY

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

Body composition in patients with non−small cell lung cancer: a contemporary view of cancer cachexia with the use of computed tomography image analysis

(2010) Vickie E Baracos et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Muscle Wasting in Cancer Cachexia: Clinical Implications, Diagnosis, and Emerging Treatment Strategies

(2010) Shontelle Dodson et al.   Annual Review of Medicine

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

Association of Skeletal Muscle Wasting With Treatment With Sorafenib in Patients With Advanced Renal Cell Carcinoma: Results From a Placebo-Controlled Study

(2010) Sami Antoun et al.   JOURNAL OF CLINICAL ONCOLOGY

Powerful signals for weak muscles

(2009) Amarjit Saini et al.   AGEING RESEARCH REVIEWS

A viscerally driven cachexia syndrome in patients with advanced colorectal cancer: contributions of organ and tumor mass to whole-body energy demands

(2009) Jessica R Lieffers et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Sarcopenia as a Determinant of Chemotherapy Toxicity and Time to Tumor Progression in Metastatic Breast Cancer Patients Receiving Capecitabine Treatment

(2009) C. M.M. Prado et al.   CLINICAL CANCER RESEARCH

Update on emerging drugs for cancer cachexia

(2009) Kate T Murphy et al.   EXPERT OPINION ON EMERGING DRUGS

The role of cytokines in cancer cachexia

(2009) Josep M Argilés et al.   Current Opinion in Supportive and Palliative Care

A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care

(2008) Marina Mourtzakis et al.   Applied Physiology Nutrition and Metabolism

Cholangiocarcinoma

(2008) Stefania Mosconi et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Inflammatory burden and amino acid metabolism in cancer cachexia

(2008) William J Durham et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

(2008) Carla MM Prado et al.   LANCET ONCOLOGY