Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma

Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma

(2013) J�rn R Henriksen et al.   BMC DEVELOPMENTAL BIOLOGY

MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma

(2011) Amanda Tivnan et al.   BMC CANCER

MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2

(2011) Ji-guang Zhang et al.   Journal of Thoracic Oncology

Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer

(2010) Yingchun Zhao et al.   BREAST CANCER RESEARCH AND TREATMENT

MYCN oncoprotein targets and their therapeutic potential

(2010) Emma Bell et al.   CANCER LETTERS

A SP1/MIZ1/MYCN Repression Complex Recruits HDAC1 at theTRKAandp75NTRPromoters and Affects Neuroblastoma Malignancy by Inhibiting the Cell Response to NGF

(2010) Nunzio Iraci et al.   CANCER RESEARCH

Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells

(2010) Jochen Buechner et al.   DIFFERENTIATION

MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion

(2010) Hui-Ju Wang et al.   EUROPEAN JOURNAL OF CANCER

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

(2010) Lars-Gunnar Larsson et al.   EXPERIMENTAL CELL RESEARCH

Therapeutic targeting of miRNAs in neuroblastoma

(2010) Raymond L Stallings et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

MicroRNA binding site polymorphisms as biomarkers of cancer risk

(2010) Cory Pelletier et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

(2010) Johannes H. Schulte et al.   INTERNATIONAL JOURNAL OF CANCER

Let-7 microRNA inhibits the proliferation of human glioblastoma cells

(2010) Soon-Tae Lee et al.   JOURNAL OF NEURO-ONCOLOGY

MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1α/HIF-1β

(2010) Paul Cao et al.   Molecular Cancer

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA Let-7a Inhibits Proliferation of Human Prostate Cancer Cells In Vitro and In Vivo by Targeting E2F2 and CCND2

(2010) Qingchuan Dong et al.   PLoS One

MYCN-regulated microRNAs repress estrogen receptor-  (ESR1) expression and neuronal differentiation in human neuroblastoma

(2010) J. Loven et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-101, Down-regulated in Hepatocellular Carcinoma, Promotes Apoptosis and Suppresses Tumorigenicity

(2009) H. Su et al.   CANCER RESEARCH

MicroRNA miR-29 Modulates Expression of Immunoinhibitory Molecule B7-H3: Potential Implications for Immune Based Therapy of Human Solid Tumors

(2009) H. Xu et al.   CANCER RESEARCH

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma

(2009) Kim Kramer et al.   JOURNAL OF NEURO-ONCOLOGY

On the road to reading the RNA-interference code

(2009) Haruhiko Siomi et al.   NATURE

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

(2008) Julia Schultz et al.   CELL RESEARCH

MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells

(2008) Antonio Strillacci et al.   EXPERIMENTAL CELL RESEARCH

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

(2008) K. A. Cole et al.   MOLECULAR CANCER RESEARCH

The MYCN oncogene is a direct target of miR-34a

(2008) J S Wei et al.   ONCOGENE

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

(2008) Frank Westermann et al.   GENOME BIOLOGY