Fenretinide-dependent upregulation of death receptors through ASK1 and p38α enhances death receptor ligand-induced cell death in Ewing's sarcoma family of tumours

Proteasome Inhibitors Enhance TRAIL-Induced Apoptosis through the Intronic Regulation of DR5: Involvement of NF- B and Reactive Oxygen Species-Mediated p53 Activation

(2014) J.-J. Chen et al.   JOURNAL OF IMMUNOLOGY

Proteasome inhibitor Bortezomib induces cell-cycle arrest and apoptosis in cell lines derived from Ewing’s sarcoma family of tumors and synergizes with TRAIL

(2010) Guangrong Lu et al.   CANCER BIOLOGY & THERAPY

Preclinical Evidence that Use of TRAIL in Ewing's Sarcoma and Osteosarcoma Therapy Inhibits Tumor Growth, Prevents Osteolysis, and Increases Animal Survival

(2010) G. Picarda et al.   CLINICAL CANCER RESEARCH

The elaboration of a critical framework for understanding cancer: the cancer stem cell hypothesis

(2010) Chris Hemmings   PATHOLOGY

Molecular Response of HL-60 Cells to Mitotic Inhibitors Vincristine and Taxol Visualized with Apoptosis-Related Gene Expressions, Including the New Member BCL2L12

(2009) Hellinida Thomadaki et al.   Annals of the New York Academy of Sciences

The promise of telomere length, telomerase activity and its regulation in the translocation-dependent cancer ESFT; clinical challenges and utility

(2009) Andrew Proctor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species

(2009) S. Yodkeeree et al.   CANCER RESEARCH

PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation

(2009) V. Appierto et al.   CARCINOGENESIS

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

Death receptor-4 (DR4) expression is regulated by transcription factor NF-κB in response to etoposide treatment

(2008) Francisco José Mendoza et al.   APOPTOSIS

Hydrogen peroxide enhances TRAIL-induced cell death through up-regulation of DR5 in human astrocytic cells

(2008) Daeho Kwon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

N -(4-Hydroxyphenyl) retinamide induced both differentiation and apoptosis in human glioblastoma T98G and U87MG cells

(2008) Arabinda Das et al.   BRAIN RESEARCH

BAY 11-7082 induces cell death through NF-κB-independent mechanisms in the Ewing’s sarcoma family of tumours

(2008) Danielle E. White et al.   CANCER LETTERS

Identification of ADP-ribosylation factor 4 as a suppressor of N-(4-hydroxyphenyl)retinamide-induced cell death

(2008) Im Sun Woo et al.   CANCER LETTERS

Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis

(2008) Holger Hetschko et al.   FEBS Journal

ABT-737 Induces Expression of the Death Receptor 5 and Sensitizes Human Cancer Cells to TRAIL-induced Apoptosis

(2008) Jin H. Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Synergy of N-(4-Hydroxyphenyl)Retinamide and ABT-737 in Acute Lymphoblastic Leukemia Cell Lines: Mcl-1 Inactivation

(2008) Min H. Kang et al.   JNCI-Journal of the National Cancer Institute

15-deoxy-Δ12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription

(2008) Rong-Ying Su et al.   MOLECULAR CANCER THERAPEUTICS

Carprofen induction of p75NTR-dependent apoptosis via the p38 mitogen-activated protein kinase pathway in prostate cancer cells

(2008) F. S. Khwaja et al.   MOLECULAR CANCER THERAPEUTICS

Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

(2008) Avi Ashkenazi   NATURE REVIEWS DRUG DISCOVERY

p53-Mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells

(2008) F Toscano et al.   ONCOGENE