Article
Oncology
Angela N. Giaquinto, Hyuna Sung, Kimberly D. Miller, Joan L. Kramer, Lisa A. Newman, Adair Minihan, Ahmedin Jemal, Rebecca L. Siegel
Summary: This article provides an update on female breast cancer statistics in the United States, including data on incidence, mortality, survival, and mammography screening. It shows that breast cancer incidence rates have increased over the past few decades, driven by localized-stage and hormone receptor-positive disease. However, breast cancer mortality rates have been steadily declining since 1989, although at a slower pace in recent years. Despite lower incidence rates, there remains a racial disparity in breast cancer mortality, with higher rates among Black women compared to White women.
CA-A CANCER JOURNAL FOR CLINICIANS
(2022)
Article
Genetics & Heredity
Leila Dorling, Sara Carvalho, Jamie Allen, Michael T. Parsons, Cristina Fortuno, Anna Gonzalez-Neira, Stephan M. Heijl, Muriel A. Adank, Thomas U. Ahearn, Irene L. Andrulis, Paivi Auvinen, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Michael Bremer, Ignacio Briceno, Nicola J. Camp, Archie Campbell, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Georgia Chenevix-Trench, J. Margriet Collee, Kamila Czene, Joe Dennis, Thilo Dork, Mikael Eriksson, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Marike Gabrielson, Manuela Gago-Dominguez, Montserrat Garcia-Closas, Graham G. Giles, Gord Glendon, Pascal Guenel, Melanie Gundert, Andreas Hadjisavvas, Eric Hahnen, Per Hall, Ute Hamann, Elaine F. Harkness, Mikael Hartman, Frans B. L. Hogervorst, Antoinette Hollestelle, Reiner Hoppe, Anthony Howell, Anna Jakubowska, Audrey Jung, Elza Khusnutdinova, Sung-Won Kim, Yon-Dschun Ko, Vessela N. Kristensen, Inge M. M. Lakeman, Jingmei Li, Annika Lindblom, Maria A. Loizidou, Artitaya Lophatananon, Jan Lubinski, Craig Luccarini, Michael J. Madsen, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Dimitrios Mavroudis, Roger L. Milne, Nur Aishah Mohd Taib, Kenneth Muir, Heli Nevanlinna, William G. Newman, Jan C. Oosterwijk, Sue K. Park, Paolo Peterlongo, Paolo Radice, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Mitul Shah, Xueling Sim, Melissa C. Southey, Harald Surowy, Maija Suvanto, Ian Tomlinson, Diana Torres, Therese Truong, Christi J. van Asperen, Regina Waltes, Qin Wang, Xiaohong R. Yang, Paul D. P. Pharoah, Marjanka K. Schmidt, Javier Benitez, Bas Vroling, Alison M. Dunning, Soo Hwang Teo, Anders Kvist, Miguel de la Hoya, Peter Devilee, Amanda B. Spurdle, Maaike P. G. Vreeswijk, Douglas F. Easton
Summary: The study found that certain rare missense variants in ATM, BRCA1, BRCA2, and CHEK2 genes may increase the risk of developing breast cancer, while missense variants in the PALB2 gene are less likely to be associated with risk.
Article
Oncology
Sabrina Wang, Farhana Sultana, Anne Kavanagh, Carolyn Nickson, Amalia Karahalios, Lyle C. Gurrin, Dallas R. English
Summary: This study aimed to quantify the impact of mammographic screening on breast cancer mortality and overdiagnosis. The results showed that women who participate in Australia's national screening program have lower breast cancer mortality, but some screen-detected cancers may be overdiagnosed.
Article
Public, Environmental & Occupational Health
Paddy Ssentongo, John S. Oh, Forster Amponsah-Manu, William Wong, Xavier Candela, Yubraj Acharya, Anna E. Ssentongo, Daleela G. Dodge
Summary: This study explored the factors influencing mortality in breast cancer in the Eastern region of Ghana and found that the survival rate in this area is low. Despite success in reducing mortality in breast cancer in northern Africa, sub-Saharan African countries still face poor outcomes. Late-stage presentation and limited accuracy in diagnosis are the main contributors to the low survival rate.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Enke Baldini, Augusto Lauro, Domenico Tripodi, Daniele Pironi, Maria Ida Amabile, Iulia Catalina Ferent, Eleonora Lori, Federica Gagliardi, Maria Irene Bellini, Flavio Forte, Patrizia Pacini, Vito Cantisani, Vito D'Andrea, Salvatore Sorrenti, Salvatore Ulisse
Summary: Epidemiological studies have shown an association between thyroid diseases and extra-thyroidal malignancies, particularly breast cancer. Patients with autoimmune thyroiditis have an increased risk of breast cancer, although the risk is lower for those who are thyroid autoantibody-positive. The molecular links between thyroid autoimmunity and breast cancer remain uncertain.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Henry J. Thompson, Elizabeth S. Neil, John N. McGinley
Summary: Population studies, systematic reviews, and meta-analyses have shown mixed results regarding the relationship between iron status and breast cancer risk, with some suggesting a protective effect and others indicating a weak positive association. Preclinical experiments did not provide convincing evidence to support further evaluation of the iron-breast cancer risk hypotheses, highlighting the need for redefining the referent group in population-based studies of iron-cancer hypotheses in other tissues.
Article
Oncology
Brian Z. Huang, Songren Wang, David Bogumil, Lynne R. Wilkens, Lang Wu, William J. Blot, Wei Zheng, Xiao-Ou Shu, Stephen J. Pandol, Loic Le Marchand, Veronica Wendy Setiawan
Summary: This study found an association between red meat consumption and pancreatic cancer risk, especially in African Americans and Latinos, with NAT2 genotypes potentially modifying this relationship. Further research should be conducted to investigate the underlying mechanisms behind the increased risk in these populations.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Hazel B. Nichols, Melissa G. House, Rina Yarosh, Sara Mitra, Mandy Goldberg, Kimberly A. Bertrand, A. Heather Eliassen, Graham G. Giles, Michael E. Jones, Roger L. Milne, Katie M. O'Brien, Julie R. Palmer, Sven Sandin, Walter C. Willett, Weiyao Yin, Dale P. Sandler, Anthony J. Swerdlow, Minouk J. Schoemaker
Summary: In this study, the data from 184,866 parous women were analyzed and it was found that preterm birth was not associated with breast cancer risk, while preeclampsia was inversely associated with breast cancer risk. However, among women with hypertensive conditions, preterm birth was positively associated with breast cancer risk. These results suggest that other conditions of pregnancy may influence the relationship between preterm birth and breast cancer.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Oncology
Emmanuel R. Ezeome, King-David T. Yawe, Omobolaji Ayandipo, Olawale Badejo, Sally N. Adebamowo, Benerdin Achusi, Adeola Fowotade, Gabriel Ogun, Clement A. Adebamowo
Summary: The AFBRECANE study aims to investigate the genomics and epidemiology of breast cancer and its molecular subtypes in Nigerian women by utilizing centralized laboratory processing and multiple technologies, linking recruitment of cases with population-based cancer registries activities. The study also involves conducting GWAS of breast cancer in an entirely indigenous African population, with a focus on associations between dietary intakes and breast cancer, particularly vitamin D. This research project is expected to make significant contributions to knowledge and understanding of breast cancer.
FRONTIERS IN ONCOLOGY
(2022)
Review
Pharmacology & Pharmacy
Yang Liu, Yueting Hu, Yi Jiang, Jiawen Bu, Xi Gu
Summary: This article introduces ferroptosis as a novel form of cell death and its potential role in breast cancer treatment.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Annelie Johansson, Athanasia E. Christakou, Adina Iftimi, Mikael Eriksson, Jose Tapia, Lambert Skoog, Christopher C. Benz, Kenny A. Rodriguez-Wallberg, Per Hall, Kamila Czene, Linda S. Lindstrom
Summary: The study found that the risk of benign breast diseases varies by age, hormonal factors, and family history of breast cancer. Factors such as nulliparity, oral contraceptive use, hormone replacement therapy, obesity, and family history were associated with different risks of various breast disease subtypes, highlighting the importance of understanding benign breast diseases for breast cancer prevention.
Article
Environmental Sciences
VA. Florez-Garcia, EC. Guevara-Romero, MM. Hawkins, LE. Bautista, TE. Jenson, J. Yu, AE. Kalkbrenner
Summary: This study evaluated the association between cadmium exposure and breast cancer incidence in women. The meta-analysis found that exposure to higher levels of cadmium increased the risk of breast cancer. Different exposure routes showed varied results, with dietary cadmium not linked to elevated risk but biomarker-based studies showing a non-significant increased risk. Rating: 8 out of 10
ENVIRONMENTAL RESEARCH
(2023)
Article
Cell Biology
Zeng-Hong Wu, Yun Tang, Hong Yu, Hua-Dong Li
Summary: A prognostic multigene signature was constructed based on ferroptosis-associated DEGs, and the roles of ferroptosis-associated miRNAs, lncRNAs, and immune responses were comprehensively analyzed, providing new insights into breast cancer prognosis.
CELL DEATH DISCOVERY
(2021)
Article
Oncology
Juliana Dalcin Donini E. Silva, Rosana Rosseto de Oliveira, Mariana Teixeira da Silva, Maria Dalva de Barros Carvalho, Raissa Bocchi Pedroso, Sandra Marisa Pelloso
Summary: The study revealed an increasing trend in breast cancer mortality rates among young women in most Brazilian states and all regions. Factors such as Human Development Index, income, and education significantly impacted the mortality rate for women aged 30-39, as well as for women aged 20-29 (only from 1996 to 2000).
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Daniel S. S. Peiffer, Fangyuan Zhao, Nan Chen, Olwen M. M. Hahn, Rita Nanda, Olufunmilayo I. I. Olopade, Dezheng Huo, Frederick M. M. Howard
Summary: A retrospective cohort study of 1,136,016 patients with ERBB2-negative and ERBB2-low breast cancer found minimal prognostic differences between the two subtypes, indicating that ERBB2-low breast cancer should not be classified as a distinct disease entity.
Article
Oncology
Seungyoun Jung, Naomi Allen, Alan A. Arslan, Laura Baglietto, Aurelio Barricarte, Louise A. Brinton, Brian L. Egleston, Roni T. Falk, Renee T. Fortner, Kathy J. Helzlsouer, Yutang Gao, Annika Idahl, Rudolph Kaaks, Vittorio Krogh, Melissa A. Merritt, Eva Lundin, N. Charlotte Onland-Moret, Sabina Rinaldi, Helena Schock, Xiao-Ou Shu, Patrick M. Sluss, Paul N. Staats, Carlotta Sacerdote, Ruth C. Travis, Anne Tjonneland, Antonia Trichopoulou, Shelley S. Tworoger, Kala Visvanathan, Elisabete Weiderpass, Anne Zeleniuch-Jacquotte, Joanne F. Dorgan
INTERNATIONAL JOURNAL OF CANCER
(2018)
Letter
Emergency Medicine
Zohar Lederman
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2020)
Article
Gastroenterology & Hepatology
Jessica L. Petrick, Andrea A. Florio, Xuehong Zhang, Anne Zeleniuch-Jacquotte, Jean Wactawski-Wende, Stephen K. Van den Eeden, Frank Z. Stanczyk, Tracey G. Simon, Rashmi Sinha, Howard D. Sesso, Catherine Schairer, Lynn Rosenberg, Thomas E. Rohan, Mark P. Purdue, Julie R. Palmer, Martha S. Linet, Linda M. Liao, I-Min Lee, Jill Koshiol, Cari M. Kitahara, Victoria A. Kirsh, Jonathan N. Hofmann, Chantal Guillemette, Barry Graubard, Edward Giovannucci, J. Michael Gaziano, Susan M. Gapster, Neal D. Freedman, Lawrence S. Engel, Dawn Q. Chong, Yu Chen, Andrew T. Chan, Patrick Caron, Julie E. Buring, Gary Bradwin, Laura E. Beane Freeman, Peter T. Campbell, Katherine A. McGlynn
Article
Oncology
Susan J. Jordan, Renhua Na, Elisabete Weiderpass, Hans-Olov Adami, Kristin E. Anderson, Piet A. van den Brandt, Louise A. Brinton, Chu Chen, Linda S. Cook, Jennifer A. Doherty, Mengmeng Du, Christine M. Friedenreich, Gretchen L. Gierach, Marc T. Goodman, Vittorio Krogh, Fabio Levi, Lingeng Lu, Anthony B. Miller, Susan E. McCann, Kirsten B. Moysich, Eva Negri, Sara H. Olson, Stacey Petruzella, Julie R. Palmer, Fabio Parazzini, Malcolm C. Pike, Anna E. Prizment, Timothy R. Rebbeck, Peggy Reynolds, Fulvio Ricceri, Harvey A. Risch, Thomas E. Rohan, Carlotta Sacerdote, Leo J. Schouten, Diego Serraino, Veronica W. Setiawan, Xiao-Ou Shu, Todd R. Sponholtz, Amanda B. Spurdle, Rachael Z. Stolzenberg-Solomon, Britton Trabert, Nicolas Wentzensen, Lynne R. Wilkens, Lauren A. Wise, Herbert Yu, Carlo La Vecchia, Immaculata De Vivo, Wanghong Xu, Anne Zeleniuch-Jacquotte, Penelope M. Webb
Summary: Full-term pregnancy is associated with reduced endometrial cancer risk, with each additional pregnancy further reducing the risk independently of age at last pregnancy. Incomplete pregnancies also show a decreased risk, indicating a protective effect of pregnancy on endometrial cancer. Twin births have a similar effect to singleton pregnancies.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Nursing
Matthew J. Peterson, Theo Woerhle, Melissa Harry, Anna Mae C. Heger, Mary Gerchman-Smith, Linda Vogel, Carolyn Hughes, Catherine McCarty
Summary: This quality improvement initiative aimed to assess the satisfaction of family members of patients in a neuro trauma ICU. Results showed that the majority of family members were satisfied with the care provided, but there were areas for improvement, particularly in noise reduction. The survey findings have been shared with leadership and considered in the planning of a new hospital building.
NURSING IN CRITICAL CARE
(2022)
Article
Oncology
Melissa A. Merritt, Howard D. Strickler, Alan D. Hutson, Mark H. Einstein, Thomas E. Rohan, Xiaonan Xue, Mark E. Sherman, Louise A. Brinton, Herbert Yu, David S. Miller, Nilsa C. Ramirez, Heather A. Lankes, Michael J. Birrer, Gloria S. Huang, Marc J. Gunter
Summary: This study identified associations between circulating estradiol and tumor tissue phosphorylated (activated) IGR1R/IR with increased risk of recurrence in patients with endometrial cancer. These findings could inform future clinical trials of endocrine-targeted adjuvant therapies for endometrial cancer patients.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Oncology
Kara A. Michels, Ashley M. Geczik, Doug C. Bauer, Louise A. Brinton, Diana S. M. Buist, Jane A. Cauley, Cher M. Dallal, Roni T. Falk, Trisha F. Hue, James V. Lacey, Andrea Z. LaCroix, Jeffrey A. Tice, Xia Xu, Britton Trabert
Summary: The study found that progestogens are generally not associated with colorectal cancer risk in postmenopausal women. These findings are consistent with prior research on circulating endogenous sex hormones, suggesting that sex hormones may not be major drivers of colorectal carcinogenesis in postmenopausal women.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Neurosciences
Catherine A. McCarty, Colleen M. Renier, Theo A. Woehrle, Linda E. Vogel, Steven D. Eyer
Summary: This study aimed to describe the epidemiology of traumatic brain injury (TBI) and quantify the differences between rural and urban areas. The study found that the risk of TBI admission among rural residents was significantly higher than that of urban residents, emphasizing the need for public health and medical interventions to reduce this disparity.
Editorial Material
Ophthalmology
Catherine A. McCarty, Hugh R. Taylor
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Health Care Sciences & Services
Josiah D. Allen, Lusi Zhang, Alyssa N. K. Johnson, Pamala A. Jacobson, Catherine A. McCarty, Amy L. Pittenger, Jeffrey R. Bishop
Summary: This study developed and validated the Minnesota Assessment of Pharmacogenomic Literacy (MAPL) to assess patients' understanding of PGx test results. The MAPL consists of 15 items that cover knowledge in four domains: underlying concepts, limitations, benefits, and privacy. The results showed good internal reliability and validity, making MAPL a useful tool for assessing PGx literacy in clinical and research settings.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Health Care Sciences & Services
Lusi Zhang, Pamala A. Jacobson, Alyssa N. K. Johnson, David B. Gregornik, Steven G. Johnson, Catherine A. McCarty, Jeffrey R. Bishop
Summary: In a survey conducted in Minnesota, the majority of residents expressed their support for receiving PGx testing and participating in PGx data sharing, especially among younger individuals with higher education, health literacy, health insurance, and prior genetic testing. Community support and engagement are crucial for advancing PGx implementation and research.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Letter
Ophthalmology
Catherine A. McCarty, Hugh Taylor
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Rebecca L. Emery Tavernier, Marcia B. Mccoy, Catherine A. Mccarty, Susan M. Mason
Summary: This study examines the differences in prepregnancy weight status and gestational weight gain between rural and urban birthing people. The findings indicate that rural birthing people have a higher risk of prepregnancy overweight or obesity and excessive gestational weight gain compared to urban birthing people. These disparities between rural and urban individuals in terms of weight-related health outcomes widen over time.
WOMENS HEALTH ISSUES
(2023)
Article
Linguistics
Laurel J. Brinton
Summary: This study examines the grammaticalization process of words like "nearly" in modern English, pointing out that the grammaticalization path of these words is different from other degree adverbs, with the degree modifier use preceding the degree adjunct use.
JOURNAL OF ENGLISH LINGUISTICS
(2021)
Article
Oncology
Kara A. Michels, Louise A. Brinton, Nicolas Wentzensen, Kathy Pan, Chu Chen, Garnet L. Anderson, Ruth M. Pfeiffer, Xia Xu, Thomas E. Rohan, Britton Trabert
JNCI CANCER SPECTRUM
(2019)