期刊
BRITISH JOURNAL OF BIOMEDICAL SCIENCE
卷 70, 期 1, 页码 6-9出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09674845.2013.11669922
关键词
Anticoagulants; Blood cell count; Potassium EDTA; Pre-analytical phase
This study assesses the use of different dry, K-2 (dipotassium) EDTA vacuum tubes and whether or not they Might represent a bias in haematological testing. Blood was collected in three dipotassium EDTA vacuum tubes from different manufacturers: Venosafe; Vacuette and Vacutainer Samples were analysed on an Advia 2120i analyser. Significant differences among results and biases were compared with current quality specifications. Significant differences were found for haematocrit (HCT), mean corpuscular volume (MCV), white blood cell Count(WBC) and platelet distribution width.(PDW) when comparing Venosafe vs. Vacuette; for MCV, WBC and PDW when comparing Venosafe vs. Vacutainer; and for HCT and MCV when comparing Vacuette vs. Vacutainer Clinically significant variations were observed for HCT and PDW in Venosafe vs. Vacuette; PDW in Venosafe vs. Vacutainer; and HCT and MCV in Vacuette. The use of dipotassium EDTA vaccum tubes from different manufacturers represent clinically relevant source of variation for HCT MCV and PDW.
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