Article
Veterinary Sciences
Daniel M. Sakai, Nicole Trenholme, Frederick J. Torpy, Hannah A. Craig, Rachel A. Reed
Summary: Sedation and anesthesia affect the EEG, and the interpretation can be aided by measuring PSI, visual inspection of DSA, and power density analysis of specific frequency bands.
RESEARCH IN VETERINARY SCIENCE
(2023)
Article
Multidisciplinary Sciences
Hideki Harada, Seiya Muta, Tatsuyuki Kakuma, Misa Ukeda, So Ota, Maiko Hirata, Hiroshi Fujioka, Osamu Nakashima, Barbara Dietel, Miyuki Tauchi
Summary: An investigational interface device was developed to connect needle electrodes to BIS sensors for surgeries where standard electrode placement is not feasible. Statistical analysis confirmed significant concordance between direct and indirect BIS values, providing an opportunity for intraoperative monitoring in patients with unconventional electrode placement.
Article
Anesthesiology
Clara Weyer, Eva Proetzl, Thomas Kinateder, Fabian Nowak, Cornelius Husemann, Hubert Hautmann, Stephan Kratzer, Gerhard Schneider, Matthias Kreuzer
Summary: The study investigated the impact of artificial alpha-band modulation on pEEG approaches used in anesthesia research, revealing different reactions of different pEEG approaches to changes in alpha-band activity. Some indicators decreased with increasing alpha activity, suggesting a deepening of anesthesia.
ANESTHESIA AND ANALGESIA
(2021)
Article
Gastroenterology & Hepatology
Yukie Hayashi, Naoki Hosoe, Kaoru Takabayashi, Kenji J. L. Limpias Kamiya, Anna Tojo, Hinako Sakurai, Satoshi Kinoshita, Tomohisa Sujino, Atsushi Nakayama, Motohiko Kato, Naohisa Yahagi, Haruhiko Ogata, Takanori Kanai
Summary: This study investigated the clinical impact of gas monitoring and BIS monitoring on hypoxic events during oral therapeutic and invasive endoscopic procedures. The results showed that apnea detected by gas monitoring was an independent predictor of hypoxia, while BIS values were not significantly associated with hypoxia events, but showed a significant downward trend before hypoxia events.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Geriatrics & Gerontology
Jian Zhan, Feng Chen, Zhuoxi Wu, Zhenxin Duan, Qiangting Deng, Jun Zeng, Lihong Hou, Jun Zhang, Yongyu Si, Kexuan Liu, Mingjun Wang, Hong Li
Summary: This study compared the consistency of anesthesia consciousness index (Ai) with that of bispectral index (BIS) in monitoring the depth of anesthesia (DOA) during sevoflurane anesthesia and revealed the optimal cutoff values in different states of consciousness. The study also explored the stability of DOA monitoring during intraoperative injurious stimulation and found that Ai and BIS showed no systematic deviation in readings with high consistency, similar accuracy, and good stability.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Anesthesiology
Roshan Simon Verghese, Sneha Raju, Eleanor Chapman
Summary: Monitoring plays a crucial role in anesthesia, offering early warning signs and reducing the risks of incidents. Techniques like neuromuscular and depth of anesthesia monitoring have become essential in anesthesia practice. This article focuses on peripheral nerve stimulators to assess neuromuscular blockade, as well as electroencephalogram analysis and stimulated evoked potentials for depth of anesthesia assessment. It discusses the physical principles, limitations, and current clinical guidance in these methodologies.
ANAESTHESIA AND INTENSIVE CARE MEDICINE
(2023)
Review
Clinical Neurology
Logan Froese, Joshua Dian, Alwyn Gomez, Carleen Batson, Amanjyot Singh Sainbhi, Frederick A. Zeiler
Summary: The impact of sedative agents on neurovascular coupling, cerebral blood flow, and cerebrovascular response remains uncertain. Objective assessments of sedation depth, particularly in traumatic brain injury, are crucial. Processed EEG entropy measures may quantify sedation depth objectively, but their association with cerebrovascular response is unclear. Further research is needed to understand the impact of sedation on neurovascular coupling.
FRONTIERS IN NEUROLOGY
(2021)
Review
Medicine, General & Internal
Chiara Grasso, Vanessa Marchesini, Nicola Disma
Summary: Research on safe anaesthesia management in children has shifted from focusing on the neurotoxic effects to prevention of critical events and maintaining peri-anaesthetic haemodynamic stability to ensure favorable neurological outcomes. Neuro-monitoring can guide anaesthesia providers in delivering optimal drugs dosages and correcting underlying conditions that can negatively affect neurological outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Editorial Material
Anesthesiology
Elizabeth L. Whitlock, Eric R. Gross, C. Ryan King, Michael S. Avidan
Summary: The study found that targeting deep anesthesia in patients undergoing major noncardiac surgery was not associated with significantly increased postoperative death or major morbidity, but it significantly increased delirium incidence. The findings may be affected by subpopulation-based differences in patients.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Review
Anesthesiology
Matthew Sumner, Carolyn Deng, Lis Evered, Chris Frampton, Kate Leslie, Timothy Short, Doug Campbell
Summary: This study found that using processed electroencephalography (pEEG)-guided general anaesthesia during surgery can reduce the incidence of postoperative delirium (POD) in older adults.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Anesthesiology
Thomas W. Schnider, Charles F. Minto
Summary: Variability is high in predicted propofol concentrations during clinical anesthesia, and improving pharmacokinetic models is unlikely to reduce variability in target anesthetic concentrations across patients in clinical practice.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Medicine, Research & Experimental
Zhitao Li, Jiachun Cai, Jiexiong Li, Xianghui Xu, Limin Zheng
Summary: The study found high correlation between BIS and BISpro, both correlating well with OAA/S scores. BIS was able to accurately distinguish all investigated OAA/S states, while the ability to predict OAA/S scores 5 to loss of response was comparable between BIS and BISpro. The calculated cut-off values were 68 for BIS and 70 for BISpro.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2021)
Article
Chemistry, Analytical
Xiaoxiao Li, Pan Chang, Xing Liu, Yi Kang, Zhongjun Zhao, Yixiang Duan, Tao Zhu, Jin Liu, Wensheng Zhang
Summary: It has been demonstrated that exhaled ciprofol concentration can be monitored online using the UV-TOFMS instrument. A correlation has been observed between exhaled ciprofol concentration and both plasma concentration and cerebral effects. This suggests the potential for using exhaled ciprofol monitoring to titrate depth of anesthesia in clinical settings.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Engineering, Biomedical
Yongkang He, Siyuan Peng, Mingjin Chen, Zhijing Yang, Yuanhui Chen
Summary: To accurately predict anesthetic effects, we propose a transformer-based method that uses drug infusions of propofol and remifentanil to predict the depth of anesthesia. Our method employs LSTM and GRN networks to improve feature fusion efficiency and applies an attention mechanism to discover the interactions between the drugs. Experimental results show that our method outperforms traditional PK-PD models and previous deep learning methods, effectively predicting anesthetic depth under sudden and deep anesthesia conditions.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Review
Anesthesiology
C. H. Prior, C. E. G. Burlinson, A. Chau
Summary: This article provides a narrative review of six areas of obstetric emergencies, focusing on recent research, practice guidelines, and recommendations. Key topics include prevention and management of complications related to neuraxial anesthesia, management of difficult and failed obstetric airway, and the use of various interventions in maternal cardiac arrest.