Article
History & Philosophy Of Science
Michael Wallner
Summary: This paper discusses the meta-grounding question and different accounts of grounding, arguing that Grounding Essentialism is more compatible with viewing grounding as metaphysical explanation.
Article
History & Philosophy Of Science
Sam Baron
Summary: Mathematics plays a crucial role in scientific explanation, particularly when pure mathematical facts and physical facts are unified under a common explanation. By exploring new scientific case studies that demonstrate this unity, it is possible to show that mathematics has its own explanatory power. Identifying potential sources of such case studies can guide future research in this area.
Article
Education & Educational Research
Sahar Alameh, Fouad Abd-El-Khalick, David Brown
Summary: Issues regarding the concept of scientific explanation have long been of interest to philosophers and science educators. However, there is a lack of research on conceptualizing explanation in science education. This study compares college freshmen science students, secondary science teachers, and practicing scientists in terms of their scientific explanations and views on scientific explanations. The analysis using a philosophically guided framework showed that scientists outperformed teachers and students. The findings highlight the need to further understand specific aspects of scientific explanation and provide an initial analytical framework for examining students' and science teachers' scientific explanations.
JOURNAL OF RESEARCH IN SCIENCE TEACHING
(2023)
Review
Biochemistry & Molecular Biology
Mohsen Akbarian, Luiz E. Bertassoni, Lobat Tayebi
Summary: This article introduces the importance of angiogenesis and factors involved in its control. In tissue engineering and regenerative medicine, angiogenesis is a crucial process for tissue repair.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2022)
Article
International Relations
Anthony Szczurek
Summary: The chapter critically analyzes and compares two climate reports produced by the Indian Government, examining the significant shifts in the State's temporal imaginary of climate change and climate politics. Through these reports, the State orients itself to the future and focuses on the development of regional-specific models, subtly resisting the imposition of a synchronized, global time of climate change.
Article
History & Philosophy Of Science
Ezequiel Lopez-Rubio, Emanuele Ratti
Summary: This paper critically examines the impact of introducing data science techniques on the characteristics and objectives of models in molecular biology. It highlights the trade-off between explanatory and predictive performance in mechanistic and predictive models. The research emphasizes that biologists must navigate the balance between explanation and prediction in the evolving landscape of biology.
Review
Oncology
Julia Elzanowska, Christine Semira, Bruno Costa-Silva
Summary: Research on DNA in extracellular vesicles (EVs) has rapidly evolved in recent years, especially in the field of liquid biopsy, but most studies have focused on RNA or protein content. This review provides a comprehensive discussion on the biology of EV-DNA, including biogenesis, loading mechanisms, and its significant roles in cellular homeostasis, communication, immune response modulation, as well as in clinical settings such as cancer, infections, pregnancy, and prenatal diagnosis.
MOLECULAR ONCOLOGY
(2021)
Article
History & Philosophy Of Science
Leonardo Bich, William Bechtel
Summary: The new mechanists and the autonomy approach aim to explain biological phenomena, with the former focusing on the organization of mechanisms and the latter on the self-maintenance of the whole organism. Collaboration between the two can benefit both: the new mechanistic framework could consider events outside individual mechanisms, while the autonomy approach could ground itself in research on how the actual components of an autonomous system interact. This integration is supported by recent developments in the autonomy tradition, including frameworks of work and constraints, a conception of function based on the organization of autonomous systems, and a focus on control.
BIOLOGY & PHILOSOPHY
(2021)
Article
Environmental Sciences
Edoardo Dell'Armi, Marta Maria Rossi, Lucia Taverna, Marco Petrangeli Papini, Marco Zeppilli
Summary: Based on the study, it can be concluded that the bioelectrochemical system using fermentable organic substrates as electron donors shows higher activity and efficiency in removing trichloroethylene pollution, compared to directly using molecular hydrogen as an electron donor. Additionally, the bioelectrochemical system achieves higher efficiency compared to the use of fermentable substrates and other chemicals.
Review
Biochemistry & Molecular Biology
Claudia Foti, Anna Piperno, Angela Scala, Ottavia Giuffre
Summary: This review provides a comprehensive overview on the chemistry, biological activity, and analytical determination of oxazolidinones, the only new class of synthetic antibiotics introduced in clinical use in the past 50 years. The unique mechanism of action and characteristics of oxazolidinones, along with the discussion on approved and under development antibiotics in this class, are highlighted. Additionally, drug delivery systems to address the poor water solubility of oxazolidinones and commonly used analytical techniques for determination are reviewed.
Article
History & Philosophy Of Science
Andre Curtis-Trudel
Summary: This article explores a wide but overlooked category of explanations in contemporary computer science, known as limitative explanations, that clarify why certain problems cannot be solved computationally. Despite their philosophical richness, limitative explanations have not received the attention they deserve. The main objectives of this article are to identify and outline the explanatory nature of limitative explanations. According to the preferred account, limitative explanations are a form of non-causal mathematical explanation that relies on highly idealized computation models.
PHILOSOPHY OF SCIENCE
(2023)
Review
Oncology
Austin C. Boucher, Kenneth J. Caldwell, John D. Crispino, Jamie E. Flerlage
Summary: Children with Down syndrome are at an elevated risk of leukemia, particularly myeloid leukemia. Treatment with reduced-intensity chemotherapy has led to excellent outcomes, but there is little understanding of the mechanisms of relapse. Future studies need to focus on this challenging aspect of leukemia in these children.
Review
Oncology
Jakub Litak, Wojciech Czyzewski, Michal Szymoniuk, Leon Sakwa, Barbara Pasierb, Joanna Litak, Zofia Hoffman, Piotr Kamieniak, Jacek Rolinski
Summary: Spine metastases are a common and life-threatening complication of advanced-stage malignancies, often with a poor prognosis. Understanding metastatic processes is crucial in order to find targeted therapeutic options. The current literature provides knowledge about molecular pathways and biomarkers involved in spine metastases, as well as current and emerging treatment options.
Review
Chemistry, Applied
Luciana Fentanes Moura de Melo, Veronica Giuliani de Queiroz Aquino-Martins, Ariana Pereira da Silva, Hugo Alexandre Oliveira Rocha, Katia Castanho Scortecci
Summary: This article explores the characteristics of tannins and their role in regulating ROS and maintaining homeostasis. Tannins have anti-inflammatory, anti-aging, and anti-proliferative properties due to their ability to bind with reactive oxygen species. They can reduce the risk of cancer and neurodegenerative diseases and also maintain a healthy gut microbiota. Tannins have industrial applications in leather durability, metal corrosion resistance, 3D printing, and bio-based foam manufacturing. This review highlights the biological and pharmacological relevance of tannins and their potential applications.
Article
Engineering, Chemical
Yixin Pan, Chen Zhang, Guodong Sheng, Manli Li, Wensheng Linghu, Rui Huang
Summary: This research developed a novel nanocomposite MoS2@FeS for the removal of U(VI) from aqueous solutions, and investigated its removal mechanism and influencing factors. The results demonstrated that MoS2@FeS exhibited superior performance compared to MoS2 in U(VI) removal under the same conditions. The adsorption processes of MoS2 and MoS2@FeS were further explored using kinetic and isotherm models.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
History & Philosophy Of Science
Andreas Huettemann
Article
Biochemistry & Molecular Biology
Guenter P. Wagner, Eric M. Erkenbrack, Alan C. Love
Editorial Material
Evolutionary Biology
Alan C. Love
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION
(2019)
Article
Evolutionary Biology
Ingo Brigandt, Laura A. Katz, Vidyanand Nanjundiah, Scott F. Gilbert, Peter R. Grant, B. Rosemary Grant, Alan C. Love, Stuart A. Newman, Mary J. West-Eberhard
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION
(2019)
Article
History & Philosophy Of Science
James DiFrisco, Alan C. Love, Gunter P. Wagner
BIOLOGY & PHILOSOPHY
(2020)
Article
History & Philosophy Of Science
Alan C. Love
PHILOSOPHY OF SCIENCE
(2020)
Article
History & Philosophy Of Science
Scott Lidgard, Alan C. Love
Summary: Researchers suggested rethinking the function of the living fossil concept, arguing that concepts in science have useful roles beyond just categorization. They discussed the diverse and sometimes conflicting criteria associated with categorizing items as living fossils and how these criteria are closely related to answering questions about prolonged evolutionary stasis.
BIOLOGY & PHILOSOPHY
(2021)
Editorial Material
Biology
Alan C. Love, Max Dresow
Article
Ecology
Alan Love, Gunter P. Wagner
Summary: It is widely accepted that stressful conditions can facilitate evolutionary change by increasing heritable variation and promoting rapid adaptive evolution. Stressors can be categorized into two types based on their effect on functional integrity: stress-responsive mechanisms that maintain adaptive fit with the environment, and stress-responsive mechanisms specific to stressors that lead to the emergence of novelties through compensation. Our model explains the evolutionary transformation of an immediate response to acute stress into routine protection from recurring stressors by considering cost-benefit trade-offs. Examples from different levels of organization support the general principle of evolutionary origination based on the ability to switch between regulatory states related to reproduction and survival.
Review
Biodiversity Conservation
Alan C. Love, Mark Grabowski, David Houle, Lee Hsiang Liow, Arthur Porto, Masahito Tsuboi, Kjetil L. Voje, Gene Hunt
Summary: This paper discusses the importance of evolvability in evolutionary biology and its application in paleontology. Despite challenges in applying tools from evolvability literature to the fossil record, the fossil record provides unique data sources that capture evolutionary patterns and assist evolutionary biologists in their research. Additionally, combining neontological and paleontological approaches is an important direction for future studies.
Article
History & Philosophy Of Science
Jose Manuel Viejo
Summary: In this paper, a new argument for Humean compatibilism is presented, suggesting that agents in a deterministic world can make choices different from what the laws determine due to the distinctive nature of Humean laws. The paper also highlights the resources that Humeans have in defending compatibilism, which non-Humeans lack, and demonstrates that utilizing these resources does not lead to objectionable consequences.
Article
History & Philosophy Of Science
Michael T. Hicks, Andreas Huettemann, Martin Voggenauer
JOURNAL FOR GENERAL PHILOSOPHY OF SCIENCE
(2022)
Article
Anatomy & Morphology
James DiFrisco, Alan C. Love, Gunter P. Wagner
Summary: This article discusses the pervasiveness of gene sharing in evolution and the issue of homology across different lineages. The authors propose a new theoretical classification to address the problem of determining homology. They argue that the concept of serial homology should primarily be applied to developmentally individualized body parts and suggest a hierarchical, phylogenetic interpretation.
JOURNAL OF MORPHOLOGY
(2023)
Letter
Ecology
Alan C. Love, Gunter P. Wagner
TRENDS IN ECOLOGY & EVOLUTION
(2023)
Article
Philosophy
Alan C. Love
