WRAD: enabler of the SET1-family of H3K4 methyltransferases

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance

(2012) Valentina Migliori et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

(2011) Hao Jiang et al.   CELL

DrosophilaSet1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription

(2011) M Behfar Ardehali et al.   EMBO JOURNAL

Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding

(2011) Yong Chen et al.   EMBO REPORTS

The COMPASS Family of H3K4 Methylases in Drosophila

(2011) M. Mohan et al.   MOLECULAR AND CELLULAR BIOLOGY

RETRACTED: The Noncoding RNA Mistral Activates Hoxa6 and Hoxa7 Expression and Stem Cell Differentiation by Recruiting MLL1 to Chromatin

(2011) Stéphane Bertani et al.   MOLECULAR CELL

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Trithorax group proteins: switching genes on and keeping them active

(2011) Bernd Schuettengruber et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain

(2011) Sabina Sarvan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Frequent Alteration of MLL3 Frameshift Mutations in Microsatellite Deficient Colorectal Cancer

(2011) Yoshiyuki Watanabe et al.   PLoS One

Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human

(2011) Y.-h. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Biochemical Insights into MLL1 Core Complex Assembly

(2011) Vanja Avdic et al.   STRUCTURE

Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1

(2010) Zain Odho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Non-SET Domain Multi-subunit Methyltransferase Required for Sequential Nucleosomal Histone H3 Methylation by the Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

(2010) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

(2010) John P. Thomson et al.   NATURE

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

PTIP Promotes Chromatin Changes Critical for Immunoglobulin Class Switch Recombination

(2010) J. A. Daniel et al.   SCIENCE

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin

(2009) Courtney M. Tate et al.   FEBS Journal

On the Mechanism of Multiple Lysine Methylation by the Human Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

(2009) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of H3K4 Trimethylation via Cps40 (Spp1) of COMPASS Is Monoubiquitination Independent: Implication for a Phe/Tyr Switch by the Catalytic Domain of Set1

(2009) Y. H. Takahashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks

(2009) Stacey M. Southall et al.   MOLECULAR CELL

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

WDR5 Interacts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket

(2008) Ji-Joon Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Conserved Arginine-containing Motif Crucial for the Assembly and Enzymatic Activity of the Mixed Lineage Leukemia Protein-1 Core Complex

(2008) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Regulation of H3K4 Trimethylation by Wdr82, a Component of Human Set1/COMPASS

(2008) M. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription factor Ap2  associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription

(2008) C. C. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA