Genome-wide association studies and Crohn's disease

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

The Pathogen Recognition Receptor NOD2 Regulates Human FOXP3+ T Cell Survival

(2010) M. K. Rahman et al.   JOURNAL OF IMMUNOLOGY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells

(2009) Yoichi Kakuta et al.   HUMAN MOLECULAR GENETICS

Contribution of IL23R but not ATG16L1 to Crohnʼs disease susceptibility in Koreans

(2009) Suk-Kyun Yang et al.   INFLAMMATORY BOWEL DISEASES

TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohnʼs disease

(2009) Nobuhiko Kamada et al.   INFLAMMATORY BOWEL DISEASES

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Activation of innate immune antiviral responses by Nod2

(2009) Ahmed Sabbah et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Use of sirolimus (rapamycin) to treat refractory Crohn's disease

(2008) D C O Massey et al.   GUT

Contribution of TNFSF15 gene variants to Crohnʼs disease susceptibility confirmed in UK population

(2008) Mark Tremelling et al.   INFLAMMATORY BOWEL DISEASES

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

(2008) Sheila A Fisher et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS