Evaluation of IGF1R and phosphorylated IGF1R as targets in HER2-positive breast cancer cell lines and tumours

Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition

(2012) A. Bielen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes

(2011) Rinat Yerushalmi et al.   BREAST CANCER RESEARCH AND TREATMENT

HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies

(2011) Devika Gajria et al.   Expert Review of Anticancer Therapy

IGF1R Signaling in Ewing Sarcoma Is Shaped by Clathrin-/Caveolin-Dependent Endocytosis

(2011) Ana Sofia Martins et al.   PLoS One

Inhibition of IGF1R activity enhances response to trastuzumab in HER-2-positive breast cancer cells

(2010) B. C. Browne et al.   ANNALS OF ONCOLOGY

Divergent effects of insulin-like growth factor-1 receptor expression on prognosis of estrogen receptor positive versus triple negative invasive ductal breast carcinoma

(2010) Hermien Hartog et al.   BREAST CANCER RESEARCH AND TREATMENT

Evaluation of a breast cancer risk prediction model expanded to include category of prior benign breast disease lesion

(2010) Rulla M. Tamimi et al.   CANCER

Type 1 Insulin-like Growth Factor Receptor Translocates to the Nucleus of Human Tumor Cells

(2010) T. Aleksic et al.   CANCER RESEARCH

A Heterozygous Mutation of the Insulin-Like Growth Factor-I Receptor Causes Retention of the Nascent Protein in the Endoplasmic Reticulum and Results in Intrauterine and Postnatal Growth Retardation

(2010) Tillmann Wallborn et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Activated Phosphoinositide 3-Kinase/AKT Signaling Confers Resistance to Trastuzumab but not Lapatinib

(2010) N. A. O'Brien et al.   MOLECULAR CANCER THERAPEUTICS

PI3K/PTEN/Akt pathway status affects the sensitivity of high-grade glioma cell cultures to the insulin-like growth factor-1 receptor inhibitor NVP-AEW541

(2010) Daniel Hägerstrand et al.   NEURO-ONCOLOGY

HER-2 Signaling and Inhibition in Breast Cancer

(2009) B. Browne et al.   CURRENT CANCER DRUG TARGETS

Synergic antitumoral effect of an IGF-IR inhibitor and trastuzumab on HER2-overexpressing breast cancer cells

(2008) A. Esparis-Ogando et al.   ANNALS OF ONCOLOGY

Co-Targeting Insulin-Like Growth Factor I Receptor and HER2: Dramatic Effects of HER2 Inhibitors on Nonoverexpressing Breast Cancer

(2008) A. K. Chakraborty et al.   CANCER RESEARCH

Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival

(2008) J. H. Law et al.   CANCER RESEARCH

HER-2 Gene Amplification, HER-2 and Epidermal Growth Factor Receptor mRNA and Protein Expression, and Lapatinib Efficacy in Women with Metastatic Breast Cancer

(2008) M. F. Press et al.   CLINICAL CANCER RESEARCH

Molecular mechanisms involved in activity of h7C10, a humanized monoclonal antibody, to IGF-1 receptor

(2008) Matthieu Broussas et al.   INTERNATIONAL JOURNAL OF CANCER

Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines

(2008) Alex J Eustace et al.   Journal of Translational Medicine