期刊
JOURNAL OF COMPARATIVE PATHOLOGY
卷 152, 期 2-3, 页码 172-176出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.jcpa.2014.10.001
关键词
dog; mammary tumour; papillomavirus
资金
- Petplan Charitable Trust
Human papillomaviruses (PVs) are found in human breast cancer tissue; however, it remains controversial as to whether these viruses play a role in the aetiology of this tumour. There has been minimal study of whether PVs are found in normal or abnormal mammary glands of animals. The present study investigated whether a PV sequence could be found in the mammary glands of 33 female dogs by rolling circle amplification and polymerase chain reaction. No PV DNA was found in normal or neoplastic canine mammary tissues, suggesting that canine PVs are probably not involved in the pathogenesis of canine mammary neoplasia. (C) 2014 Elsevier Ltd. All rights reserved.
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