Deletion of the amyloid precursor-like protein 1 (APLP1) enhances excitatory synaptic transmission, reduces network inhibition but does not impair synaptic plasticity in the mouse dentate gyrus

Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity

(2014) Meike Hick et al.   ACTA NEUROPATHOLOGICA

The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons

(2014) B. Wang et al.   JOURNAL OF NEUROSCIENCE

Differential role of APP and APLPs for neuromuscular synaptic morphology and function

(2014) Maja Klevanski et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Upregulation of APP, ADAM10 and ADAM17 in the Denervated Mouse Dentate Gyrus

(2014) Domenico Del Turco et al.   PLoS One

Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression

(2014) Sascha W Weyer et al.   Acta Neuropathologica Communications

Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo

(2013) Peter Jedlicka et al.   Brain Structure & Function

Redundancy and divergence in the amyloid precursor protein family

(2013) S. Ali M. Shariati et al.   FEBS LETTERS

Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function

(2012) Brea Midthune et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

APP physiological and pathophysiological functions: insights from animal models

(2011) Qinxi Guo et al.   CELL RESEARCH

APLP1 and Rab5A Interact with the II-III loop of the Voltage-gated Ca2+-channel Cav2.3 and Modulate its Internalization Differently

(2011) Kayalvizhi Radhakrishnan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP

(2011) Sascha W Weyer et al.   EMBO JOURNAL

The amyloid precursor protein and its homologues: Structural and functional aspects of native and pathogenic oligomerization

(2011) Daniela Kaden et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Functional consequences of the lack of amyloid precursor protein in the mouse dentate gyrus in vivo

(2011) Peter Jedlicka et al.   EXPERIMENTAL BRAIN RESEARCH

The role of APP and APLP for synaptic transmission, plasticity, and network function: lessons from genetic mouse models

(2011) Martin Korte et al.   EXPERIMENTAL BRAIN RESEARCH

Structural aspects and physiological consequences of APP/APLP trans-dimerization

(2011) Frederik Baumkötter et al.   EXPERIMENTAL BRAIN RESEARCH

Functions of the APP gene family in the nervous system: insights from mouse models

(2011) Dorothee Aydin et al.   EXPERIMENTAL BRAIN RESEARCH

Increased Dentate Gyrus Excitability in Neuroligin-2-Deficient Mice in Vivo

(2010) P. Jedlicka et al.   CEREBRAL CORTEX

Computational modeling of GABAA receptor-mediated paired-pulse inhibition in the dentate gyrus

(2010) Peter Jedlicka et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

(2009) Kristin T. Jacobsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2

(2009) D. Kaden et al.   JOURNAL OF CELL SCIENCE

Amyloid Precursor Protein Regulates Cav1.2 L-type Calcium Channel Levels and Function to Influence GABAergic Short-Term Plasticity

(2009) L. Yang et al.   JOURNAL OF NEUROSCIENCE

Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis

(2009) Z. Wang et al.   JOURNAL OF NEUROSCIENCE

Increased network excitability and impaired induction of long-term potentiation in the dentate gyrus of collybistin-deficient mice in vivo

(2009) Peter Jedlicka et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Down-regulation of APLP1 mRNA expression in hippocampus of pilocarpine-induced epileptic rats

(2009) Cheng Wang et al.   Neuroscience Bulletin

Impairment of in vivo theta-burst long-term potentiation and network excitability in the dentate gyrus of synaptopodin-deficient mice lacking the spine apparatus and the cisternal organelle

(2008) Peter Jedlicka et al.   HIPPOCAMPUS

Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates

(2008) Tomás R. Guilarte et al.   JOURNAL OF NEUROCHEMISTRY

Embryonic Stem Cell-Derived Neurons as a Cellular System to Study Gene Function: Lack of Amyloid Precursor Proteins APP and APLP2 Leads to Defective Synaptic Transmission

(2008) Katrin Schrenk-Siemens et al.   STEM CELLS