Article
Ecology
Cristian Salgado-Luarte, Marcia Gonzalez-Teuber, Karina Madriaza, Ernesto Gianoli
Summary: There is a trade-off between plant resistance and tolerance. The study found a negative relationship between mechanical defenses and tolerance, while there was no significant association between chemical defenses and tolerance. Plant adaptation to light environments may affect the trade-off between resistance and tolerance.
Article
Ecology
Olivia L. L. Brooks, Jessie J. J. James, Ralph A. A. Saporito
Summary: The alkaloid defenses of the strawberry poison frog vary within and among populations, impacting the level of protection against predators and pathogens. The alkaloid composition of mother frogs is reflected in the composition of their tadpoles, with greater quantities of alkaloids leading to better protection.
Review
Plant Sciences
Boaz Negin, Georg Jander
Summary: The majority of plant specialized metabolites serve as defense mechanisms against herbivores, with identical or structurally distinct compounds repeatedly targeting the same herbivorous animals. This may be due to constraints in plant primary metabolism and limited accessible targets in animals. The complex biosynthetic pathways of unique defensive compounds in individual genera or species may complicate their repeated evolution in different plant species.
CURRENT OPINION IN PLANT BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Rashaduz Zaman, Courtney May, Aziz Ullah, Nadir Erbilgin
Summary: This study investigated the impact of three fungal symbionts on the terpene chemistry of pine trees and found that these fungi can alter host defense chemicals, assist beetles in overcoming metabolite toxicity, and potentially provide chemical cues for attracting bark beetles.
Article
Chemistry, Multidisciplinary
Jiheon Kim, Sanghyeon Lee, Sunkyu Han, Hee-Yoon Lee
Summary: Since its discovery in 2002, conidiogenone has been extensively studied and used as a platform for the development of synthetic strategies. However, most approaches focused on the construction of the core structure, while a divergent synthetic approach for D-ring modifications remained unknown. In this study, a divergent synthesis of six conidiogenones, including three total syntheses, was achieved using a synthetic strategy that involved the use of TMM-mediated cycloaddition and subsequent D-ring diversifications.
Editorial Material
Chemistry, Multidisciplinary
Hyung Min Chi, Pengfei Hu, Scott A. Snyder
Summary: The researchers demonstrate the construction of the tetracyclic framework of the conidiogenone family in one step using a cascade reaction starting from a material with one ring and appropriate functional groups.
Review
Biochemistry & Molecular Biology
Jessica P. Yactayo-Chang, Anna K. Block
Summary: Climate change has a significant impact on the production and effectiveness of maize chemical defenses, including the production of volatile organic compounds, terpenoid phytoalexins, benzoxazinoids, phenolics, and flavonoids. Drought, flooding, heat stress, and elevated carbon dioxide concentrations affect the production of these defense chemicals in a tissue-specific manner. Changes in stomatal conductance and altered soil conditions also impact the environmental dispersal and effectiveness of these chemicals, leading to complex interactions and challenges in predicting their response to multiple stressors. Further research is needed to effectively utilize these protective chemicals for climate-resilient maize.
BIOCHEMICAL JOURNAL
(2023)
Review
Ecology
Maria-Jose Endara, Dale L. Forrister, Phyllis D. Coley
Summary: This study summarizes current trends in the study of plant-herbivore interactions and their impact on plant chemical defenses, host choice, and community diversity. Defense investment variation is driven by resource availability, and deeper nodes of plant phylogeny exhibit conservative evolution of defenses. In tropical ecosystems, greater specialization of herbivores reduces the performance of plants with similar defenses, while in temperate ecosystems with more generalist herbivores, rare defense profiles are at a disadvantage. Herbivore host choice is primarily influenced by plant defenses rather than host phylogeny, leading to evolutionary tracking by herbivores instead of coevolution. The interaction between plants and herbivores shapes both the origin and maintenance of diversity.
ANNUAL REVIEW OF ECOLOGY EVOLUTION AND SYSTEMATICS
(2023)
Review
Biochemistry & Molecular Biology
Ivan Sestari, Marcelo Lattarulo Campos
Summary: Plants use chemical defenses to protect themselves from pests and pathogens, but the antagonism between growth and defense may have originated from the evolutionary history of plants. Recent theories are exploring ways to overcome this growth versus chemical defense dilemma, in order to breed highly defensive plants without compromising growth.
PLANT MOLECULAR BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Zhenggao Xiao, Ningke Fan, Wenqing Zhu, Hai-Long Qian, Xiu-Ping Yan, Zhenyu Wang, Sergio Rasmann
Summary: The application of nanosilicon has been found to enhance plant defenses against various stresses. Silicon quantum nanodots, with their unique biological and physiochemical properties, show promise in regulating plant responses to stress. By studying maize, it was observed that the addition of Si NDs and sodium silicate effectively inhibited the growth of caterpillars and activated defense genes. Field experiments also demonstrated the potential of Si NDs in increasing maize yield. These findings suggest that Si NDs can be an effective and ecofriendly crop protection strategy in agroecosystems.
Review
Chemistry, Medicinal
Kelvin Jianmin Voon, Yasodha Sivasothy, Usha Sundralingam, Aicha Lalmahomed, Asly Poh-Tze Goh
Summary: This review discusses the distribution, extraction, isolation, and characterization methods of labdane-type diterpenes in the Zingiberaceae plants. It also explores the cytotoxic activities of these compounds against various cancer cell lines and the influence of their structural features.
Article
Ecology
Amy M. Trowbridge, Henry D. Adams, Adam Collins, Lee Turin Dickman, Charlotte Grossiord, Megan Hofland, Shealyn Malone, David K. Weaver, Sanna Sevanto, Paul C. Stoy, Nate G. McDowell
Summary: Heat and drought have synergistic effects on increasing monoterpene concentrations in mature pinon pines, while decreasing key monoterpenes that play important roles in bark beetle ecology. This highlights the complex and potentially detrimental impacts of combined stressors on plant chemical defenses.
Article
Multidisciplinary Sciences
Steven W. J. Canty, Graeme Fox, Jennifer K. Rowntree, Richard F. Preziosi
Summary: The study found low genetic diversity among coral colonies in hope spots like Cordelia Bank, but demonstrated subtle genetic differences within and among banks. Despite approximately 30% clonality across each bank, each identified genotype within the banks was unique.
SCIENTIFIC REPORTS
(2021)
Editorial Material
Cell Biology
Yi Ding, Avinash Bhandoola
Summary: Liu et al. used single-cell RNA sequencing to determine the proportions of ILCs in human fetal tissues, and identified novel progenitor subsets undergoing ILC lineage specification in fetal liver.
Article
Biochemistry & Molecular Biology
Matheus L. Silva, Thais A. Costa-Silva, Guilherme M. Antar, Andre G. Tempone, Joao Henrique G. Lago
Summary: The hexane extract of Baccharis sphenophylla displayed activity against amastigote forms of Trypanosoma cruzi, leading to the isolation of one unreported diterpene (1) and three known diterpenes. Compounds 1 and 7 showed effectiveness against the parasite with low toxicity against NCTC cells, indicating their potential as prototypes for developing novel drugs against intracellular forms of T. cruzi.
CHEMISTRY & BIODIVERSITY
(2021)
Editorial Material
Biotechnology & Applied Microbiology
Ricardo Coutinho, Pio Colepicolo, Eliane Marinho-Soriano, Estela M. Plastino, Mutue T. Fujii, Valeria L. Teixeira, Nair S. Yokoya, Yocie Yoneshigue-Valentin
JOURNAL OF APPLIED PHYCOLOGY
(2017)
Review
Biochemistry & Molecular Biology
Marina Cyrino Leal Coutinho, Valeria Laneuville Teixeira, Cinthya Simone Gomes Santos
JOURNAL OF CHEMICAL ECOLOGY
(2018)
Article
Chemistry, Medicinal
Rebeca Cristina Costa Pereira, Andre Luiz Lourenco, Luciana Terra, Paula Alvarez Abreu, Valeria Laneuville Teixeira, Helena Carla Castro
Article
Medicine, Legal
Valeria Garrido, Caroline Barros, Vanessa A. Melchiades, Rainomar Raimundo Fonseca, Sergio Pinheiro, Patricia Ocampo, Valeria L. Teixeira, Diana N. Cavalcanti, Viveca Giongo, Norman A. Ratcliffe, Gerlinde Teixeira, Izabel Christina N. P. Paixao
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2017)
Article
Biotechnology & Applied Microbiology
Michelle Marchezan F. de Mesquita, Mirian A. C. Crapez, Valeria L. Teixeira, Diana N. Cavalcanti
JOURNAL OF APPLIED PHYCOLOGY
(2019)
Article
Plant Sciences
Joel Campos De-Paula, Erick Alves Pereira Lopes-Filho, Fabiano Salgueiro, Yocie Yoneshigue-Valentin, Diana Negrao Cavalcanti, Roberto Campos Villaca, Valeria Laneuville Teixeira
NEW ZEALAND JOURNAL OF BOTANY
(2018)
Review
Fisheries
Ana Carolina Calheiros, Renata Perpetuo Reis, Beatriz Castelar, Diana Negrao Cavalcanti, Valeria Laneuville Teixeira
Article
Chemistry, Medicinal
Valeria Laneuville Teixeira, Juliana Coelho Rodrigues Lima, Guilherme Curty Lechuga, Carlos Jose Brito Ramos, Mirian Claudia de Souza Pereira, Claudia Magalhaes Calvet, Saulo Cabral Bourguignon
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
(2019)
Article
Chemistry, Medicinal
Graziela Holken Lorensi, Raquel Soares Oliveira, Allan P. Leal, Ana Paula Zanatta, Carlos Gabriel Moreira de Almeida, Yuri Correia Barreto, Maria Eduarda Rosa, Patricia de Brum Vieira, Carlos Jose Brito Ramos, Filipe de Carvalho Victoria, Antonio Batista Pereira, Valeria Laneuville Teixeira, Chariston Andre Dal Belo
Article
Multidisciplinary Sciences
Claudio Cesar Cirne-Santos, Caroline de Souza Barros, Mariana Cavalcante de Oliveira, Vitor Won-Held Rabelo, Renata Campos Azevedo, Valeria Laneuville Teixeira, Davis Fernandes Ferreira, Izabel Christina Nunes de Palmer Paixao
SCIENTIFIC REPORTS
(2020)
Article
Chemistry, Applied
Mariana Martinelli Junqueira Ribeiro, Ana Carolina Renno Sodero, Nuria Cirauqui Diaz, Valeria Laneuville Teixeira, Carlos Rangel Rodrigues, Alessandra Mendonca Teles de Souza
Summary: HIV is a public health problem, and natural products such as diterpenes may have potential in inhibiting HIV entry and treatment. In silico tools can be used to evaluate the mechanism of action and properties of these natural products.
NATURAL PRODUCT RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
N. L. vonRanke, M. M. J. Ribeiro, L. A. Miceli, N. P. de Souza, B. A. Abrahim-Vieira, H. C. Castro, V. L. Teixeira, C. R. Rodrigues, A. M. T. Souza
Summary: In this study, molecular modeling techniques were used to investigate marine natural products with anti-HIV activity. The results suggest that dolabelladienetriol may have the potential to be developed as an effective antiretroviral drug, based on its interaction with the allosteric site of HIV-1 reverse transcriptase and its ability to induce conformational changes in the enzyme. The in silico ADMET simulations also support the promising prospects of dolabelladienetriol as a drug candidate.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Article
Chemistry, Medicinal
Claudio Cesar Cirne-Santos, Caroline de Souza Barros, Priscilla Oliveira Esteves, Max Willian Lisboa Gomes, Rafaela dos Santos Pereira Gomes, Diana Negrao Cavalcanti, Johana Marcela Concha Obando, Carlos Jose Brito Ramos, Roberto Campos Villaca, Valeria Laneuville Teixeira, Izabel Christina Nunes de Palmer Paixao
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
(2020)
Article
Engineering, Environmental
Amanda Cunha de Souza Coracao, Fernanda Silva dos Santos, Jorge Andres Duarte Duarte, Erick Alves Pereira Lopes-Filho, Joel Campos De-Paula, Leandro Machado Rocha, Natascha Krepsky, Sorele Batista Fiaux, Valeria Laneuville Teixeira
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2020)
Article
Plant Sciences
C. J. B. Ramos, R. R. Fonseca, A. P. S. Souza Filho, V. L. Teixeira