Review
Nutrition & Dietetics
Reeta Ala-Jaakkola, Arja Laitila, Arthur C. Ouwehand, Liisa Lehtoranta
Summary: Urinary tract infections (UTIs) are a common bacterial disease worldwide, and antibiotic resistance is a major concern. D-mannose, a dietary supplement, shows promise as an alternative treatment for UTIs, reducing the risk and recurrence.
Article
Immunology
Robin Patel, Christopher R. Polage, Jennifer Dien Bard, Larissa May, Francesca M. Lee, Valeria Fabre, Mary K. Hayden, Sarah D. B. Doernberg, David A. Haake, Barbara W. Trautner, Larissa Grigoryan, Ephraim L. Tsalik, Kimberly E. Hanson
Summary: Urinary tract infections (UTIs) are common bacterial infections in the United States and contribute significantly to antibiotic use in healthcare settings. Novel UTI diagnostics have the potential to improve healthcare delivery, patient outcomes, and antibiotic use.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Microbiology
Lei Huang, Chenwei Huang, Yan Yan, Liying Sun, Haixia Li
Summary: This study compared the etiological profiles and antibiotic resistance patterns of urinary tract infections (UTIs) sorted by different age categories. The study found that the pathogens and antibiotic resistance varied among different age groups, especially in pediatric and geriatric patients. Therefore, different antibiotic therapies should be considered for different age categories when initiating empirical antimicrobial therapies.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Public, Environmental & Occupational Health
N. Salari, Y. Khoshbakht, M. Hemmati, Y. Khodayari, A. A. Khaleghi, F. Jafari, S. Shohaimi, M. Mohammadi
Summary: The global prevalence of urinary tract infections (UTIs) in pregnant women was found to be 23.9% based on a systematic review and meta-analysis. The study also identified that an increase in sample size and study year was associated with a decrease in UTI prevalence in pregnant women.
Article
Microbiology
Arturo Artero, Ian Lopez-Cruz, Juan Alberola, Jose Maria Eiros, Elena Resa, Laura Piles, Manuel Madrazo
Summary: Urinary tract infection (UTI) is common in the elderly and can lead to sepsis. This study aimed to investigate the middle-term prognosis of elderly patients with UTI and its association with sepsis. The study found that sepsis had a detrimental impact on the middle-term prognosis of elderly patients with UTI, and age, functional status, and healthcare-associated UTIs also played significant roles in shaping patient outcomes.
Article
Obstetrics & Gynecology
Bahati Johnson, Bawakanya Mayanja Stephen, Ngonzi Joseph, Owaraganise Asiphas, Kayondo Musa, Kabanda Taseera
Summary: This study found a high prevalence of UTI during pregnancy, with gram-negative bacteria being the most common and resistant to multiple antibiotics. This highlights the need for careful consideration in the treatment of UTI during pregnancy.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Review
Public, Environmental & Occupational Health
Xiaoyan Li, Qing Yu, Feng Qin, Biyu Zhang, Yanming Lu
Summary: This study found that serum vitamin D levels were significantly lower in children with urinary tract infections compared to healthy controls, indicating a significant negative relationship between serum vitamin D levels and the risk of urinary tract infections in children.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Infectious Diseases
Rajani Dube, Shatha Taher Salman Al-Zuheiri, Mariyam Syed, Lekshmi Harilal, Dean Allah Layth Zuhaira, Subhranshu Sekhar Kar
Summary: This research aimed to estimate the prevalence, clinical and bacteriological profile, antibiotic resistance, and risk factors of symptomatic UTI in pregnant women. The study involved giving pregnant women a pre-validated questionnaire for UTI symptoms, conducting urine microscopy, culture, and sensitivity tests for symptomatic patients, and providing treatment and follow-up. The analysis showed that regular antenatal care and routine urine testing in all visits are recommended for early detection and treatment of UTI.
Article
Pediatrics
Nader Shaikh, Marcia Kurs-Lasky, Hui Liu, Vinod Rajakumar, Heba Qureini, Isabella O. Conway, Matthew C. Lee, Sojin Lee
Summary: This study compared the accuracy of urinary biomarkers to that of the leukocyte esterase (LE) dipstick test for pediatric urinary tract infection (UTI) screening. Urinary neutrophil gelatinase-associated lipocalin (NGAL), IL-1 beta, CXCL1, and IL-8 were found to be the most effective biomarkers for distinguishing febrile children with and without UTI. The urinary NGAL test had a sensitivity of 90% and a specificity of 96%. The importance of further investigation into the cost-effectiveness of urinary NGAL as a screening test for UTI is emphasized.
FRONTIERS IN PEDIATRICS
(2023)
Article
Infectious Diseases
Seyedeh Elham Rezatofighi, Mahsa Mirzarazi, Mansour Salehi
Summary: UTI, caused by UPEC, is a common bacterial infectious disease with significant morbidity. The genetic structure and virulence factors of UPEC vary between clinical and commensal isolates, with B2 and D phylogenetic groups strongly associated with UPEC. Understanding the epidemiology and characteristics of UPEC isolates in different regions is crucial for controlling UTI. Interfering with intestinal colonization, particularly in pathogenic clonal lineages like B2, may help reduce the burden of UTI.
BMC INFECTIOUS DISEASES
(2021)
Article
Microbiology
Kavindra Singh, Barbara E. Murray
Summary: In a mouse model of urinary tract infection, omadacycline demonstrated comparable efficacy to gentamicin and superior efficacy to ciprofloxacin against a tetracycline-resistant, ciprofloxacin-resistant strain of Escherichia coli. Additionally, omadacycline showed better efficacy than ciprofloxacin against this resistant strain. Further research is warranted to explore the potential of omadacycline as a treatment option for urinary tract infections caused by ciprofloxacin-resistant E. coli strains.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Microbiology
Timothy J. Straub, Wen-Chi Chou, Abigail L. Manson, Henry L. Schreiber, Bruce J. Walker, Christopher A. Desjardins, Sinead B. Chapman, Kerrie L. Kaspar, Orsalem J. Kahsai, Elizabeth Traylor, Karen W. Dodson, Meredith A. J. Hullar, Scott J. Hultgren, Christina Khoo, Ashlee M. Earl
Summary: While cranberry juice consumption had minimal impact on the overall gut microbiome, a significant difference was found in the abundance of an unnamed Flavonifractor species between study arms. Further research is needed to assess the role of cranberry consumption and this species in the context of health and wellbeing in cases of recurrent UTIs.
Review
Medicine, General & Internal
Tomislav Mestrovic, Mario Matijasic, Mihaela Peric, Hana Cipcic Paljetak, Anja Baresic, Donatella Verbanac
Summary: The current research focuses on the relationship between gut microbiota and the development of bacteriuria and UTI, as well as the potential impact of vaginal dysbiosis and urinary microbiome perturbations on infections. Further research and exploration are needed to understand and potentially utilize these findings for the diagnosis and treatment of UTIs.
Article
Infectious Diseases
Luciano Garofalo, Claudia Nakama, Douglas Hanes, Heather Zwickey
Summary: Urobiome dysbiosis is a common problem in women with uncomplicated urinary tract infection. Traditional antibiotics are not effective in addressing this issue, so new treatment approaches are needed. A whole-person, multi-modal approach may be more effective in reducing recurrent UTI.
Article
Microbiology
Nicolas Vautrin, Kevin Alexandre, Martine Pestel-Caron, Estelle Bernard, Roland Fabre, Marie Leoz, Sandrine Dahyot, Francois Caron
Summary: Recurrent cystitis is a common disease in women, mainly caused by uropathogenic Escherichia coli. Our study demonstrates the importance of personalized treatment and prevention for cystitis.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Bita Balzhshi, Nasim Afshari, Fatemeh Fallah
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2018)
Article
Infectious Diseases
Bita Bakhshi, Arezoo Dehghan-Mouriaabadi, Parisa Kiani
MICROBIAL DRUG RESISTANCE
(2018)
Article
Immunology
Mandi Ghorbanalizadgan, Bita Bakhshi, Shahin Najar-Peerayeh
MICROBIAL PATHOGENESIS
(2018)
Article
Multidisciplinary Sciences
Shabnam Zeighamy Alamdary, Bita Bakhshi, Sara Soudi
Review
Infectious Diseases
Neda Baseri, Shahin Najar-Peerayeh, Fahime Bagheri Amiri
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
(2018)
Article
Biochemical Research Methods
Emanuela Bonaiuto, Massimiliano Magro, Luca Fasolato, Enrico Novelli, Saeed Shams, Alessandra Piccirillo, Bita Bakhshi, Tahereh Tohidi Moghadam, Davide Baratella, Fabio Vianello
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2018)
Article
Chemistry, Analytical
Zahra Dehghani, Morteza Hosseini, Javad Mohammadnejad, Bita Bakhshi, Ali Hossein Rezayan
Article
Cell Biology
Seyyed Khalil Shokouhi Mostafavi, Shahin Najar-Peerayeh, Ashraf Mohabbati Mobarez, Mehdi Kardoust Parizi
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Article
Multidisciplinary Sciences
Reza Golmohammadi, Shahin Najar-Peerayeh, Tahereh Tohidi Moghadam, Seyed Mohammad Javad Hosseini
SCIENTIFIC REPORTS
(2020)
Article
Infectious Diseases
Samira Tajik, Shahin Najar-Peerayeh, Bita Bakhshi
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
(2020)
Article
Immunology
Zahra Raahati, Bita Bakhshi, Shahin Najar-peerayeh
JOURNAL OF IMMUNOLOGY RESEARCH
(2020)
Article
Genetics & Heredity
Maryam Talebi, Shahin Najar-Peerayeh, Bita Bakhshi
Correction
Infectious Diseases
Shahin Najar-Peerayeh
ARCHIVES OF CLINICAL INFECTIOUS DISEASES
(2020)
Article
Endocrinology & Metabolism
Hanieh-Sadat Ejtahed, Zahra Hoseini-Tavassol, Shohre Khatami, Mehrangiz Zangeneh, Ava Behrouzi, Sara Ahmadi Badi, Arfa Moshiri, Shirin Hasani-Ranjbar, Ahmad-Reza Soroush, Farzam Vaziri, Abolfazl Fateh, Mostafa Ghanei, Saeid Bouzari, Shahin Najar-Peerayeh, Seyed Davar Siadat, Bagher Larijani
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2020)
Article
Pharmacology & Pharmacy
Zeinab Sharafi, Bita Bakhshi, Jaber Javidi, Sina Adrangi
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
(2018)