Article
Clinical Neurology
Mohd Faizal Mohd Zulkifly, Ornela Merkohitaj, Juergen Brockmoeller, Walter Paulus
Summary: The study investigated the impact of caffeine on brain plasticity and found that it increased motor cortex excitability in caffeine-naive subjects, enhanced PAS 25 effects, and affected alertness and motor evoked potentials under light deprivation. Time of day had no effect on tACS-induced plasticity in caffeine consumers.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Health Care Sciences & Services
Lijuan Wang, Michael A. Nitsche, Volker R. Zschorlich, Hui Liu, Zhaowei Kong, Fengxue Qi
Summary: The study showed that 20 Hz tACS during action observation reduced motor cortex excitability and subsequently inhibited execution-related motor cortex excitability. The effects of tACS on task-related motor cortex excitability are frequency-dependent, with 20 Hz showing more significant effects compared to 10 Hz.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Multidisciplinary Sciences
Akiyoshi Matsugi, Satoru Nishishita, Kyota Bando, Yutaka Kikuchi, Keigo Tsujimoto, Yuto Tanabe, Naoki Yoshida, Hiroaki Tanaka, Shinya Douchi, Takeru Honda, Masato Odagaki, Hideki Nakano, Yohei Okada, Nobuhiko Mori, Koichi Hosomi
Summary: This study aimed to investigate abnormalities in inhibitory cortical excitability and motor control during ballistic-targeting movements in individuals with degenerative cerebellar ataxia (DCA). The results indicated that individuals with DCA showed longer cortical silent period (cSP), suggesting excessive activity in the inhibitory cortical circuit. However, this increase in inhibitory activity did not contribute to the control of ballistic-targeting movements and did not correlate with the severity of ataxia. These findings contribute to our understanding of motor control abnormalities in people with DCA and provide potential evidence for further research in this area.
SCIENTIFIC REPORTS
(2023)
Article
Clinical Neurology
Sangtae Ahn, Flavio Frohlich
Summary: This study provides causal evidence that the early TEP components reflect cortical reactivity to TMS, with the earliest component localized to the left M1, the following components mainly localized to the primary somatosensory cortex, and the later components largely localized to the auditory cortex. Transcranial direct current stimulation selectively modulated cortical and corticospinal excitability by modulating the pre-stimulus mu-rhythm oscillatory power.
Article
Neurosciences
Jin Zhang, Wen-Hao Huang, Ya-Dan Zheng, Xin Li, Hao-Xiang Jiang, Min-Zhi Su, Xiao-Yan Huang, Zu-Lin Dou, Zhi-Ming Tang
Summary: The study found that auricular acupuncture can modulate the excitability of the motor cortex area controlling the upper limbs. MEP amplitude, tapping score, and tapping speed significantly increased under the real stimulation condition, while decreased under the sham stimulation condition.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Asher Geffen, Nicholas Bland, Martin V. Sale
Summary: The study investigated the effects of slow oscillatory (SO) tACS on motor cortical excitability and found that tACS had a facilitatory effect on motor cortical excitability that outlasted stimulation. However, there was no evidence supporting entrainment of endogenous oscillations as the underlying mechanism.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Vincenzo Rizzo, Carmen Terranova, Giovanni Raffa, Salvatore Massimiliano Cardali, Filippo Flavio Angileri, Giuseppina Marzano, Maria Catena Quattropani, Antonino Germano, Paolo Girlanda, Angelo Quartarone
Summary: Brain tumors can lead to abnormal cortical excitability in affected hemispheres, with decreased SICI, ICF, and SAI. Further research is needed to investigate the relationship between cortical excitability and motor impairment in these patients.
FRONTIERS IN NEUROLOGY
(2021)
Review
Neurosciences
Danny Adrian Spampinato, Jaime Ibanez, Lorenzo Rocchi, John Rothwell
Summary: Transcranial magnetic stimulation (TMS) is a non-invasive technique used to study the human brain. One outcome measure of TMS is the motor-evoked potential (MEP), which estimates changes in corticospinal excitability. This article summarizes the neural pathways and circuits contributing to MEP generation, discusses factors to consider when interpreting MEP amplitude in motor processing and neurological conditions, and explores how emerging technologies can enhance understanding of neural substrates influencing MEPs.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Multidisciplinary Sciences
Lukas Schilberg, Sanne Ten Oever, Teresa Schuhmann, Alexander T. Sack
Summary: The study found that MEP amplitude is correlated to alpha phase, alpha power, and beta phase, indicating the modulatory effect of these factors on corticospinal excitability fluctuations.
Article
Neurosciences
Lingdi Fu, Lorenzo Rocchi, Ricci Hannah, Guizhi Xu, John C. Rothwell, Jaime Ibanez
Summary: The study highlights the importance of timing in inducing plastic changes in corticospinal excitability (CSE) by associating peripheral nerve stimulation with electromyogram (EMG) activity just before movement initiation. Furthermore, it demonstrates that background voluntary muscle activity can abolish the effect on CSE, suggesting that synapses inactive at rest but anticipating movement play a crucial role in plasticity induction.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Article
Psychiatry
Jonas Rauh, Anne S. M. Mueller, Guido Nolte, Moritz Haaf, Marius Mussmann, Saskia Steinmann, Christoph Mulert, Gregor Leicht
Summary: This study investigated the effects of non-invasive brain stimulation on working memory performance. The results show that under specific conditions, using transcranial alternating current stimulation at a frequency of 5 Hz on the left dorsolateral prefrontal cortex can significantly improve working memory performance.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Rehabilitation
Yan Gong, Xian-Ming Long, Ying Xu, Xiu-Ying Cai, Ming Ye
Summary: The study demonstrated that 1Hz rTMS combined with anodal tDCS stimulation protocol showed significant effects on motor function and cortex excitability in subacute stroke patients, making it a potential preferred rehabilitative strategy for motor recovery.
CLINICAL REHABILITATION
(2021)
Article
Neurosciences
Meng-Xin Wang, Aihaiti Wumiti, Yao-Wen Zhang, Xue-Sheng Gao, Zi Huang, Meng-Fei Zhang, Zhi-Yong Peng, Yoshitaka Oku, Zhi-Ming Tang
Summary: The aim of this study was to investigate the effect of transcutaneous cervical vagus nerve stimulation (tcVNS) on motor cortex excitability in healthy adults. The results showed that after real stimulation, the amplitude of motor-evoked potential (MEP) significantly increased, while MEP latency and rest motor threshold (rMT) significantly decreased. This suggests that tcVNS can improve motor cortex excitability.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Neurosciences
Andrea Guerra, Valentina D'Onofrio, Francesco Asci, Florinda Ferreri, Giovanni Fabbrini, Alfredo Berardelli, Matteo Bologna
Summary: L-dopa variably influences the effects of iTBS-gamma-tACS on M1 in PD patients. However, the combination of iTBS-gamma-tACS therapy improved M1 plasticity and enhanced GABA-A-ergic transmission in PD patients regardless of dopaminergic state.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Mohd Faizal Mohd Zulkifly, Albert Lehr, Daniel van de Velden, Asad Khan, Niels K. Focke, Carsten H. Wolters, Walter Paulus
Summary: Interindividual anatomical differences in the human cortex can lead to variability in the response of transcranial electrical stimulation methods. This study aimed to explore the effects of personalized multi-electrode stimulation montages on the somatosensory cortex using 140 Hz transcranial alternating current stimulation (tACS). The results showed a decrease in oscillatory mu-rhythms during and after tactile discrimination tasks, indicating the involvement of the somatosensory system. However, on a group level, tACS did not significantly modulate oscillatory power and evoked potential amplitudes.
Article
Neurosciences
Marta Poyo Solanas, Minye Zhan, Maarten Vaessen, Ruud Hortensius, Tahnee Engelen, Beatrice de Gelder
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2018)
Review
Multidisciplinary Sciences
Ruud Hortensius, Emily S. Cross
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2018)
Article
Multidisciplinary Sciences
Ruud Hortensius, Solene Neyret, Mel Slater, Beatrice de Gelder
Article
Computer Science, Artificial Intelligence
Ruud Hortensius, Felix Hekele, Emily S. Cross
IEEE TRANSACTIONS ON COGNITIVE AND DEVELOPMENTAL SYSTEMS
(2018)
Article
Biology
Emily S. Cross, Katie A. Riddoch, Jaydan Pratts, Simon Titone, Bishakha Chaudhury, Ruud Hortensius
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2019)
Article
Biology
Emily S. Cross, Ruud Hortensius, Agnieszka Wykowska
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2019)
Review
Behavioral Sciences
Melike M. Fourie, Ruud Hortensius, Jean Decety
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2020)
Review
Neurosciences
Anna Henschel, Ruud Hortensius, Emily S. Cross
TRENDS IN NEUROSCIENCES
(2020)
Article
Neurosciences
Ruud Hortensius, Michaela Kent, Kohinoor M. Darda, Laura Jastrzab, Kami Koldewyn, Richard Ramsey, Emily S. Cross
Summary: This study investigated the relationship between anthropomorphism and theory-of-mind, finding that while these two concepts may overlap in certain situations, they remain separate at the personality level.
HUMAN BRAIN MAPPING
(2021)
Article
Criminology & Penology
Sofia Seinfeld, Ruud Hortensius, Jorge Arroyo-Palacios, Guillermo Iruretagoyena, Luis E. Zapata, Beatrice de Gelder, Mel Slater, Maria V. Sanchez-Vives
Summary: Domestic violence has long-term negative consequences on children. In this study, men with a history of partner aggression and a control group were placed in virtual reality as a child's perspective to witness a scene of domestic violence. The study found that the experience mainly affected the recognition of angry facial expressions and physiological responses during explicit violent events. This research demonstrates the potential of virtual reality in the rehabilitation and neuropsychological assessment of males with a history of domestic violence.
JOURNAL OF INTERPERSONAL VIOLENCE
(2023)
Article
Neurosciences
Ann Hogenhuis, Ruud Hortensius
Summary: In this exploratory study, the researchers analyzed functional MRI data to investigate the similarities and differences in neural activation when participants conversed with a human or a robot. The results showed that listening to a robot, compared to a human, led to higher activation in the language network and the person perception network, but no differences were found in the theory-of-mind network. Functional connectivity analysis revealed no differences in within- and between-network connectivity between interactions with a human or robot.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Robotics
Fabiola Diana, Misako Kawahara, Isabella Saccardi, Ruud Hortensius, Akihiro Tanaka, Mariska E. Kret
Summary: This study examines the influence of cultural background on explicit and implicit attitudes towards robots. The findings suggest that Japanese individuals have a more positive explicit attitude towards robots compared to Dutch individuals, but there is no difference at the implicit level. Cultural background and robot embodiment do not influence implicit preferences towards humans.
INTERNATIONAL JOURNAL OF SOCIAL ROBOTICS
(2023)
Article
Robotics
Ilja Croijmans, Laura van Erp, Annelie Bakker, Lara Cramer, Sophie Heezen, Dana Van Mourik, Sterre Weaver, Ruud Hortensius
Summary: The level of interpersonal trust can be influenced by smell, but this impact may not extend to trust in social robots.
INTERNATIONAL JOURNAL OF SOCIAL ROBOTICS
(2023)
Proceedings Paper
Computer Science, Artificial Intelligence
Rosanne H. Timmerman, Te-Yi Hsieh, Anna Henschel, Ruud Hortensius, Emily S. Cross
Summary: The study showed that third-party encounters influenced participants’ behavior during the game, but not their attitudes towards the observed agents. Participants exhibited more effort towards robots, especially when framed as competitive in the observation phase.
SOCIAL ROBOTICS, ICSR 2021
(2021)
Article
Psychology, Multidisciplinary
Ruud Hortensius, Beatrice de Gelder
CURRENT DIRECTIONS IN PSYCHOLOGICAL SCIENCE
(2018)
