Article
Neurosciences
Taylor J. Bosch, Christopher Groth, Tiffany A. Eldridge, Etienne Z. Gnimpieba, Lee A. Baugh, Arun Singh
Summary: The study demonstrates abnormalities in cerebellar oscillations during cognitive and motor processing in patients with Parkinson's disease, indicated by changes in alpha and theta band power, as well as reduced speed and increased dispersion in tasks. Connectivity differences were also observed between certain electrodes during motor tasks.
Article
Neurosciences
Taylor J. Bosch, Arturo I. Espinoza, Arun Singh
Summary: Studies have found dysfunctional connectivity between cortico-basal ganglia and cerebellar networks in Parkinson's disease (PD). Abnormal cerebellar oscillations have been observed in people with PD during rest, motor, and cognitive tasks. However, the role of cerebellar oscillations during lower-limb movements in PD patients with freezing of gait (PDFOG+) has not been studied. This study used EEG electrodes to evaluate cerebellar oscillations during cue-triggered lower-limb pedaling movements in PDFOG+ patients, PDFOG- patients, and healthy individuals.
Editorial Material
Biochemistry & Molecular Biology
Meike E. van der Heijden, Amanda M. Brown, Roy V. Sillitoe
Summary: A new study demonstrates that in developing rats, an internal model for movement emerges in the postnatal thalamus and relies on signals from the cerebellum for precise motor function.
Article
Neurosciences
Antonello Baldassarre, Maria Serena Filardi, Sara Spadone, Stefania Della Penna, Giorgia Committeri
Summary: The study found that rates of early and late post-training motor skill learning were positively correlated with the strength of functional connections among regions within the brain. Early learning was associated with connections within cerebellar regions, while late learning was related to connections between cortical and subcortical motor areas. This suggests that spontaneous brain activity carries behaviorally relevant information for experience-dependent cognitive operations over time.
Article
Neurosciences
Benjamin Parrell, Hyosub E. Kim, Assaf Breska, Arohi Saxena, Richard Ivry
Summary: Research shows that cerebellar degeneration affects adaptive responses in reaching and speech production, with no significant differences in compensatory responses. Furthermore, individuals with cerebellar degeneration exhibit impairments in feedforward control, while feedback control remains largely intact.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Engineering, Biomedical
Susan Aliakbaryhosseinabadi, Romulus Lontis, Dario Farina, Natalie Mrachacz-Kersting
Summary: The study investigated the effect of different task complexity on EEG signals during motor learning. Results showed that complex training led to a significant decrease in Beta band power and increase in Gamma band power, particularly in frontal and central regions. Performance variations were mainly correlated with changes in beta and gamma power. Additionally, connectivity between frontal and central regions significantly increased in the complex training group.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2021)
Article
Computer Science, Artificial Intelligence
Massimo Grillo, Alice Geminiani, Cristiano Alessandro, Egidio D'Angelo, Alessandra Pedrocchi, Claudia Casellato
Summary: This study presents a spike-based computational model of a Bayesian estimator, which optimally integrates neural activities to drive sensory feedback and cerebellar prediction in different learning stages. This model is crucial for simulations of sensorimotor tasks in integrated spiking, brain-inspired control systems.
NEURAL COMPUTATION
(2022)
Article
Computer Science, Artificial Intelligence
Masahiko Fujita
Summary: This paper discusses the compensation mechanism for time delays in neural signal processing and the role of the cerebellum in predictive control. By studying the timing-dependent plasticity of parallel fiber-Purkinje cell synapses, the theory proposes that a temporal difference of 50-200 ms is the basis for associative anticipation. This study integrates the universal function approximation capability of the cerebellar cortex model and temporally asymmetric synaptic plasticity to create the theory of associative anticipatory learning of the cerebellum.
Article
Physiology
Laurent M. Arsac
Summary: The study suggests that a better understanding of executive control in the human movement system can be gained through complex fractal analysis, and that individuals with high motor skills are able to maintain good adaptability in the face of concurrent tasks.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Abdulraheem Nashef, Rea Mitelman, Ran Harel, Mati Joshua, Yifat Prut
Summary: Our study on correlated firing between motor thalamic and cortical cells in monkeys performing a delayed-response reaching task revealed positive and negative correlations between thalamic cells and primary motor cortex activity, as well as premotor cortex activity around movement onset. This functional cooperation and opposition between the motor thalamus and distinct motor cortical areas with specific roles in planning vs. performing movements suggests that the motor thalamus can facilitate the transition from a motor plan to execution by enhancing and suppressing motor and premotor firing.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Amelia D. Chapman, Samantha Selhorst, Julia LaComb, Alexis LeDantec-Boswell, Timothy R. Wohl, Subhodip Adhicary, Corinne M. Nielsen
Summary: Intercellular influences play a crucial role in the coordinated development and function of vascular and neural components in the brain. This study shows that endothelial deletion of Rbpj leads to neurovascular abnormalities in mice, affecting cerebellar morphogenesis and lamination. These abnormalities also result in impaired motor behaviors. These findings suggest that Rbpj is necessary for proper cerebellar outgrowth, morphogenesis, and function in early postnatal vascular endothelium.
Review
Behavioral Sciences
Carlos Albaladejo-Garcia, Fernando Garcia-Aguilar, Francisco J. Moreno
Summary: Inhibitory control, closely related to sports practice, was studied in this systematic review and meta-analysis within the Stop-Signal Paradigm. The analysis showed that athletes have a shorter stop-signal reaction time compared to non-athletes, and this effect is influenced by age. This suggests that extensive practice in competitive environments can improve inhibitory control, particularly in young athletes.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Neurosciences
Adam W. Kiefer, Cortney N. Armitano-Lago, Brian L. Cone, Scott Bonnette, Christopher K. Rhea, Sarah Cummins-Sebree, Michael A. Riley
Summary: The study found that the late childhood group exhibited longer and faster/more variable COP trajectories, while displaying less regularity in their COP sway position. In contrast, the mid-adolescent group showed greater regularity in their COP speed under closed eyes condition.
Article
Clinical Neurology
Bianca Vieira-Yano, Douglas N. Martini, Fay B. Horak, Andrea de Lima-Pardini, Filipe Almeida, Vagner P. Santana, Daniel Lima, Alana X. Batista, Raquel Marquesini, Jumes Lira, Egberto R. Barbosa, Daniel M. Corcos, Carlos Ugrinowitsch, Carla Silva-Batista
Summary: The adapted resistance training with instability (ARTI) can improve gait automaticity and attentional set-shifting in freezers. Compared to traditional motor rehabilitation, ARTI training is more effective in improving gait speed, stride length, and CLR activation.
MOVEMENT DISORDERS
(2021)
Article
Psychology, Biological
Scott T. Albert, Jihoon Jang, Hannah R. Sheahan, Lonneke Teunissen, Koenraad Vandevoorde, David J. Herzfeld, Reza Shadmehr
Summary: This study suggests that human motor adaptation has an upper limit linked to implicit learning. The sensitivity of the implicit learning system to errors decreases as perturbation variability increases, affecting the overall adaptation limit.
NATURE HUMAN BEHAVIOUR
(2021)
Article
Psychiatry
Li Kong, Christina J. Herold, Eric F. C. Cheung, Raymond C. K. Chan, Johannes Schroeder
SCHIZOPHRENIA BULLETIN
(2020)
Article
Neuroimaging
Xin Di, Zhiguo Zhang, Bharat B. Biswal
Summary: PPI is a method for studying task modulated connectivity by including physiological variables as covariates. Generalized PPI can yield similar results to direct contrast between conditions. PPI and BSC can detect similar connectivity differences based on context sensitive changes in effective connectivity.
BRAIN IMAGING AND BEHAVIOR
(2021)
Article
Neurosciences
Hang Yang, Hong Zhang, Xin Di, Shuai Wang, Chun Meng, Lin Tian, Bharat Biswal
Summary: Recent studies have shown that there is significant dynamic information in resting-state fMRI and have identified recurring states dominated by similar coactivation patterns (CAPs). The reproducibility and generalizability of CAP analysis were investigated in this study, revealing six reliable CAP states and their dynamic characteristics. Additionally, aberrant CAP states in schizophrenia were found to be associated with symptom severity.
Article
Neurosciences
Linling Li, Xin Di, Huijuan Zhang, Gan Huang, Li Zhang, Zhen Liang, Zhiguo Zhang
Summary: This study found that the patterns of brain interactions induced by nociceptive pain are significantly different from those of other sensory modalities, and pain is more likely to modulate the overall functional connectivity of the brain, providing new insights into the neural mechanisms of pain processing.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Ziyan Wu, Meng Cao, Xin Di, Kai Wu, Yu Gao, Xiaobo Li
Summary: This study found that there were functional brain alterations in both white matter and gray matter in patients with traumatic brain injury (TBI), which were associated with attention deficits. Compared to the normal control group, TBI patients showed significant changes in nodal efficiency and degree in certain regions, which may contribute to behavioral deficits in the attention domain.
Article
Neurosciences
Hang Yang, Hong Zhang, Chun Meng, Afra Wohlschlaeger, Felix Brandl, Xin Di, Shuai Wang, Lin Tian, Bharat Biswal
Summary: This study investigates the coactivation pattern (CAP) of the resting-state human brain at different frequency sub-bands. It finds that CAPs exhibit frequency-dependent characteristics, with higher frequency bands showing shorter persistence and more between-state transitions. The study also reveals significant alterations in CAP persistence in schizophrenia patients.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Xin Di, Marie Woelfer, Simone Kuehn, Zhiguo Zhang, Bharat B. Biswal
Summary: The influences of environmental factors such as weather on the human brain are still largely unknown. In this study, machine learning regression was used to predict weather and environmental parameters using resting-state functional MRI (fMRI) data. The results showed that daylight length and air temperatures can be reliably predicted using resting-state parameters, but similar accuracies can also be achieved using EPI or anatomical images.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Xin Di, Bharat B. Biswal
Summary: This study used principal component analysis to examine individual differences in brain responses during movie watching. The results showed evidence of two consistent responses in the supramarginal gyrus and other regions, highlighting the importance of identifying multiple consistent responses to naturalistic stimuli.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Meng Li, Lena Vera Danyeli, Lejla Colic, Gerd Wagner, Stefan Smesny, Tara Chand, Xin Di, Bharat B. Biswal, Jorn Kaufmann, Juergen R. Reichenbach, Oliver Speck, Martin Walter, Zuemruet Duygu Sen
Summary: Reproducible resting-state functional connectivity patterns and their alterations have significant implications in neuropsychiatric research. This study utilizes multimodal imaging and magnetic resonance spectroscopy to investigate the correlation between regional neurotransmitter levels and rsFC strength, providing insights into the modulation of interaction between brain regions at a macroscopic level.
HUMAN BRAIN MAPPING
(2022)
Article
Anatomy & Morphology
Xin Di, Zhiguo Zhang, Ting Xu, Bharat B. Biswal
Summary: This study examined the dynamic and stationary connectivity in the brain when participants watched different movie clips. Consistent dynamic connectivity patterns were observed for each clip, showing differences between the clips. The dynamic connectivity could classify the movie clips more accurately than stationary connectivity and regional activity, reflecting functional brain changes.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Neurosciences
Heming Zhang, Xin Di, Bart Rypma, Hang Yang, Chun Meng, Bharat Biswal
Summary: The conventional approach to investigating functional connectivity in a block-designed study may reduce the purity of the blood oxygenation level-dependent signal. Recent studies suggest that the continuous design can provide a better understanding of task-related functional connectivity. This study used repeated-measures analysis to investigate the separable effects of block/continuous design on task-related functional connectivity networks.
NEUROSCIENCE BULLETIN
(2023)
Article
Psychology, Developmental
Xin Di, Ting Xu, Lucina Q. Uddin, Bharat B. Biswal
Summary: Spatially remote brain regions exhibit dynamic functional interactions across various task conditions. While time-varying functional connectivity during movie watching shows sensitivity to movie content, stationary functional connectivity remains relatively stable across videos. These findings suggest that dynamic and stationary functional interactions may represent different aspects of brain function. However, the relationship between individual differences in time-varying and stationary connectivity and behavioral phenotypes remains elusive.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2023)
Article
Psychology, Developmental
Han-yu Zhou, Han-xue Yang, Li-juan Shi, Simon S. Y. Lui, Eric F. C. Cheung, Raymond C. K. Chan
Summary: The study found that adolescents with higher levels of autistic traits had more difficulty distinguishing visual stimuli in time and were more likely to perceive sound-leading audiovisual pairings as simultaneous. Reduced visual temporal acuity, rather than auditory or multisensory temporal processing, was correlated with more atypical patterns of sensory responsiveness. Additionally, the positive correlation between visual TOJ thresholds and sensory avoidance was only present in adolescents with relatively high levels of autistic traits.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2021)
Meeting Abstract
Psychiatry
Mathilde Antoniades, Igor Nenadic, Tilo Kircher, Alex Krug, Tina Meller, Dominik Grotegerd, Alex Fornito, Aurina Arnatkeviciute, Udo Dannlowski, Pamela DeRosse, Ashley Moyett, Bernhard Baune, Melissa Green, Yann Quide, Christos Pantelis, Raymond C. K. Chan, Yi Wang, Ulrich Ettinger, Martin Debbane, Melodie Derome, Christian Gaser, Bianca Besteher, Kelly Diederen, Thomas Spencer, Wulf Rossler, Lukasz Smigielski, Veena Kumari, Haeme Park, Kristina Wiebels, Imke Lemmers-Jansen, Paul Allen, Petya Kozhuharova, Jan-Bernard Marsman, James Gilleen, Matthias Kirschner, Alain Dagher, Irina Lebedeva, Alexander Tomyshev, Stefan Kaiser, Anne-Kathrin Fett, Iris Sommer, Theo G. M. van Erp, Jessica A. Turner, Paul M. Thompson, Andre Aleman, Gemma Modinos
SCHIZOPHRENIA BULLETIN
(2020)
Meeting Abstract
Psychiatry
Xinlu Cai, Yongming Wang, Hanyu Zhou, Jia Huang, Simon S. Y. Lui, Arne Moller, Henry K. F. Mak, Eric F. C. Cheung, Raymond C. K. Chan
SCHIZOPHRENIA BULLETIN
(2020)
