期刊
JOURNAL OF COLLOID AND INTERFACE SCIENCE
卷 457, 期 -, 页码 329-338出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2015.07.012
关键词
Green synthesis; Silver nanoparticles; Anticancer activity; Antimicrobial activity; Skin cancer; Phytochemical; Dynamic light scattering; Zeta potential; FTIR; Fe-SEM
资金
- National Institute of Technology, Rourkela
Hypothesis: Biological synthesis of silver nanoparticles is a cost effective natural process where the phytochemicals specifically phenols, flavonoids and terpenoids present in the plant extracts act as capping and reducing agent. Due to their nano size regime the silver nanoparticles may directly bind to the DNA of the pathogenic bacterial strains leading to higher antimicrobial activity. Experiment: In the current study silver nanoparticles were synthesised using plant extracts from different origin Cucurbita maxima (petals), Moringa oleifera (leaves) and Acorus calamus (rhizome). The synthesised nanoparticles were characterized by UV-visible spectroscopy, dynamic light scattering (DLS), X-ray diffraction (XRD), field emission scanning electron microscopy (Fe-SEM) and Fourier transform infrared spectroscopy (FTIR). Finding: Highly crystalline, roughly spherical and cuboidal silver nanoparticles of 30-70 nm in size were synthesised. The nanoparticles provided strong antimicrobial activity against pathogenic strains. The effect of the synthesised nanoparticles against A431 skin cancer cell line was tested for their toxicity by 3-(4,5-dimethylthiazol-2-y1)-2,5-diphenyltetrazolium bromide (MU) dye. The IC50 values of 82.39 +/- 3.1, 83.57 +/- 3.9 and 78.58 +/- 2.7 mu g/ml were calculated for silver nanoparticles synthesised by C. maxima, M. oleifera and A. calamus respectively. (C) 2015 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据