Article
Neurosciences
Ronald Sladky, Andreas Hahn, Inga-Lisa Karl, Nicole Geissberger, Georg S. Kranz, Martin Tik, Christoph Kraus, Daniela M. Pfabigan, Andreas Gartus, Rupert Lanzenberger, Claus Lamm, Christian Windischberger
Summary: Using dynamic causal modeling, this study investigated the central role of the OFC in regulating amygdala activation during emotional face processing, demonstrating that the OFC downregulates amygdala activation, rather than the DLPFC or VLPFC.
BRAIN CONNECTIVITY
(2022)
Article
Behavioral Sciences
Mijna Hadders-Algra
Summary: This review emphasizes the importance of face and gaze signals in non-verbal social communication, as well as the impact of culture and race on the perception and processing of facial information. Research suggests that the brain utilizes two parallel and interacting pathways for the processing of facial identity, emotional expression, and gaze, involving different cortical regions.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Neurosciences
Kaho Tsumura, Reiko Shintaki, Masaki Takeda, Junichi Chikazoe, Kiyoshi Nakahara, Koji Jimura
Summary: This study investigated how response inhibition is achieved under perceptual uncertainty, revealing the roles and interactions of different brain regions in this process, further elucidating the complexity of neural mechanisms involved.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Psychology, Multidisciplinary
Vasudeva Murthy Challakere Ramaswamy, Tony Butler, Bianca Ton, Kay Wilhelm, Philip B. Mitchell, Lee Knight, David Greenberg, Andrew Ellis, Val Gebski, Peter William Schofield
Summary: This study examined the relationship between olfactory deficits and traumatic brain injury in impulsive violent offenders. The results showed that olfactory identification ability was associated with age, cognitive ability, impulsivity, TBI severity, social connectedness, childhood sexual abuse, suicidality, and heroin use. These findings suggest that olfactory testing may have utility in further studies of offenders.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Prachi Patel, Kiki van der Heijden, Stephan Bickel, Jose L. Herrero, Ashesh D. Mehta, Nima Mesgarani
Summary: The representation of spatially separated simultaneous talkers and the modulation of neural representations of attended and unattended speech by talkers' locations and voices in the human auditory cortex are still unclear. This study measured neural responses from patients with implanted electrodes and found that spatial separation between talkers caused preferential encoding of contralateral speech. The location and spectrotemporal features of talkers were encoded in different aspects of neural response.
Article
Neurosciences
Leena Ali Ibrahim, Shuhan Huang, Marian Fernandez-Otero, Mia Sherer, Yanjie Qiu, Spurti Vemuri, Qing Xu, Robert Machold, Gabrielle Pouchelon, Bernardo Rudy, Gord Fishell
Summary: The study reveals that the establishment of top-down connectivity in the primary visual cortex critically depends on early thalamic inputs during postnatal development. Thalamic inputs predominantly target neurogliaform cells in layer 1, facilitating the subsequent strengthening of top-down inputs from the anterior cingulate cortex onto these cells. Sensory deprivation or removal of thalamic afferents blocks this phenomenon, highlighting the importance of bottom-up inputs for the development of top-down connections in the visual cortex.
Article
Neurosciences
Murad Atmaca, Muhammed Fatih Tabara, Mustafa Koc, Mehmet Gurkan Gurok, Sema Baykara, Sevda Korkmaz, Osman Mermi
Summary: The aim of this study was to investigate whether there were significant differences in the cortical thickness of the orbitofrontal cortex (OFC) region between patients with alcohol use disorder and healthy control subjects. The results showed that patients with alcohol use disorder had significantly reduced volumes and thinner cortical thickness of the OFC compared to healthy controls. It is suggested that the OFC region appears to be statistically significantly smaller in patients with alcohol use disorder in terms of both cortical thickness and volume. Future research should focus on longitudinal relationships and the causality of the association with treatment response.
Article
Psychology, Multidisciplinary
Vasudeva Murthy Challakere Ramaswamy, Tony Butler, Bianca Ton, Kay Wilhelm, Philip B. Mitchell, Lee Knight, David Greenberg, Andrew Ellis, Stephen Allnutt, Jocelyn Jones, Val Gebski, Vaughan Carr, Rodney J. Scott, Peter William Schofield
Summary: Traumatic brain injury is associated with impulsive violent behavior, and the occurrence rate of traumatic brain injury is high among impulsive violent offenders, with relevance to the severity and frequency of the injury.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Multidisciplinary Sciences
Yonatan Vanunu, Jared M. Hotaling, Mike E. Le Pelley, Ben R. Newell
Summary: The study shows that initial attention in risky choice is driven by perceptual properties of the stimulus, while subsequent choices are more influenced by goal-driven factors. Options with the highest values and largest font sizes have the greatest impact on choice, while distractors may attract attention but do not affect actual decision-making.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Juan Diaz-Colunga, Nanxi Lu, Alicia Sanchez-Gorostiaga, Chang-Yu Chang, Helen S. Cai, Joshua E. Goldford, Mikhail Tikhonov, Alvaro Sanchez
Summary: Microbial communities frequently invade one another as a whole, a phenomenon known as community coalescence. This study provides direct evidence that collective invasions can lead to ecological coselection in microbial communities due to cross-feeding interactions at the community level.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Review
Neurosciences
Benjamin Schuman, Shlomo Dellal, Alvar Pronneke, Robert Machold, Bernardo Rudy
Summary: The brain relies on the ability of the neocortex to integrate sensory information with internal signals in order to make quick adjustments to behavior, with pyramidal cells in layer 1 playing a crucial role. Layer 1 serves as the primary input layer for top-down information, contributing to functions such as sensory perception, cross-modal integration, controlling states of consciousness, attention, and learning.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 44, 2021
(2021)
Article
Automation & Control Systems
T. Burr, S. Croft, A. Favalli, T. Krieger, B. Weaver
Summary: This paper reviews progress and presents new results for uncertainty quantification in nuclear safeguards, focusing on data-driven choices in SD estimation, the use of approximate Bayesian computation, computational calibration, revisions to the GUM, and critique of a Unified Theory of Measurement Errors and Uncertainties.
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
(2021)
Article
Multidisciplinary Sciences
Victor Pando-Naude, Agata Patyczek, Leonardo Bonetti, Peter Vuust
Summary: The human brain has the ability to integrate information from the environment with internally generated content, but the integration of top-down and bottom-up processes during complex multi-modal human activities is yet to be fully understood. Music listening leads to the urge to move, and music making entails both playing and listening, requiring different brain structures to process similar information.
SCIENTIFIC REPORTS
(2021)
Correction
Neurosciences
Qi Cheng, Chengyu T. Li
Summary: A correction to the paper has been published.
NEUROSCIENCE BULLETIN
(2021)
Article
Biology
Hajo Eicken, Finn Danielsen, Josephine-Mary Sam, Maryann Fidel, Noor Johnson, Michael K. Poulsen, Olivia A. Lee, Katie Spellman, Lisbeth Iversen, Peter Pulsifer, Martin Enghoff
Summary: Effective responses to rapid environmental change rely on observations to inform planning and decision-making. Comparing top-down, large-scale program driven approaches with bottom-up approaches initiated and steered at the community level can yield benefits, especially when connecting to Indigenous and local knowledge.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Qiaojun Qu, Huilong Nie, Shuang Hou, Feng Wang, Kunshan He, Panxia Deng, Shangqiu Chen, Zeyu Zhang, Chongwei Chi, Zhenhua Hu, Hong Shan, Jie Tian
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Biochemical Research Methods
Lishuang Guo, Meishan Cai, Xiaoning Zhang, Zeyu Zhang, Xiaojing Shi, Xiaojun Zhang, Jiangang Liu, Zhenhua Hu, Jie Tian
Summary: This study explored a novel weighted auxiliary set matching pursuit (WASMP) method to enhance the accuracy of CLT reconstruction. The experiments showed that the WASMP method achieved superior performance in terms of positional accuracy and shape recovery.
JOURNAL OF BIOPHOTONICS
(2022)
Article
Computer Science, Interdisciplinary Applications
Yaxin Shang, Zechen Wei, Hui Hui, Xiaohu Li, Liang Li, Yongqiang Yu, Ligong Lu, Li Li, Hongjun Li, Qi Yang, Meiyun Wang, Meixiao Zhan, Wei Wang, Guanghao Zhang, Xiangjun Wu, Li Wang, Jie Liu, Jie Tian, Yunfei Zha
Summary: Automatic segmentation of infected regions is essential for the diagnosis and assessment of COVID-19 pneumonia. In this study, a two-stage hybrid UNet method is proposed, which achieves accurate segmentation of infected regions. Furthermore, a 3D-ResNet model is trained for COVID-19 pneumonia screening. The results show that the proposed approach performs well in various evaluation metrics and can serve as an efficient assisting tool for radiologists in COVID-19 diagnosis from CT images.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2022)
Article
Computer Science, Artificial Intelligence
Liwen Zhang, Lianzhen Zhong, Cong Li, Wenjuan Zhang, Chaoen Hu, Di Dong, Zaiyi Liu, Junlin Zhou, Jie Tian
Summary: This study proposes a novel approach for predicting the overall survival risk of human cancer patients based on CT images. By using a multi-task network with tailored attention modules, the method improves the accuracy of OS risk prediction and achieves good results in clinical stage prediction.
Article
Oncology
Xiaojun Zeng, Wen Zhu, Wenjun Lin, Jie Tian, Jian Yang, Chihua Fang
Summary: This article introduces the feasibility of laparoscopic extended right posterior sectionectomy and related methods, and demonstrates that virtual liver segment projection and ICG fluorescence imaging can improve the accuracy of the surgery.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Editorial Material
Oncology
Xiaojun Zeng, Wen Zhu, Wenjun Lin, Jie Tian, Jian Yang, Chihua Fang
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Jingbo Wang, Siyi Li, Kun Wang, Ling Zhu, Lin Yang, Yunjing Zhu, Zhen Zhang, Longwei Hu, Yuan Yuan, Qi Fan, Jiliang Ren, Gongxin Yang, Weilong Ding, Xiaoyu Zhou, Junqi Cui, Chunye Zhang, Ying Yuan, Ruimin Huang, Jie Tian, Xiaofeng Tao
Summary: Real-time fluorescence imaging can improve the detection rate of tumor margins in oral squamous cell carcinoma (SCC) patients. The feasibility of using c-MET-binding peptide-indocyanine green (cMBP-ICG) for intraoperative detection of tumor margins was evaluated in a clinical trial. The application of cMBP-ICG showed high sensitivity and moderate specificity in detecting tumor margins in oral SCC patients.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Changjian Li, Jiahui Mi, Yueqi Wang, Zeyu Zhang, Xiaoyong Guo, Jian Zhou, Zhenhua Hu, Jie Tian
Summary: Fast identification of tumor area is crucial during lung cancer surgery. This study developed a new technology using fluorescent probes to define tumor boundaries and distinguish metastatic lymph nodes, thus improving surgical accuracy.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiangjun Wu, Bingxi He, Pengli Gao, Peng Zhang, Yaxin Shang, Liwen Zhang, Jing Zhong, Jingying Jiang, Hui Hui, Jie Tian
Summary: This article proposes a deep learning method to address the sparse-view reconstruction problem in projection MPI. By constructing a simulated data set and using novel projections generated by a projection generative network (PGNet), the temporal resolution of 3D imaging in projection MPI is improved while suppressing streaking artifacts.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yueqi Wang, Changjian Li, Jiaming Zhuo, Hui Hui, Bing Zhou, Jie Tian
Summary: This study presents a dual-reaction fluorescent probe named DR-1, which visualizes Fe(II) and ROS simultaneously, offering great potential to explore the mechanism of ferroptosis both in vitro and in vivo.
MOLECULAR IMAGING AND BIOLOGY
(2023)
Review
Chemistry, Analytical
Xiaohua Jia, Guodong Shen, Jia Jia, Yan Zhang, Dan Zhang, Wanjun Li, Jianjun Zhang, Xinglu Huang, Jie Tian
Summary: This article introduces the importance of cancer stem cells and the method of lineage tracing, as well as the application of molecular imaging in the dynamic detection of cancer stem cells. The article analyzes the current situation and looks forward to the future development of cancer stem cell detection.
Article
Oncology
Bao Li, Fengling Li, Zhenyu Liu, FangPing Xu, Guolin Ye, Wei Li, Yimin Zhang, Teng Zhu, Lizhi Shao, Chi Chen, Caixia Sun, Bensheng Qiu, Hong Bu, Kun Wang, Jie Tian
Summary: This study aimed to explore the predictive information for pCR from WSIs in breast cancer patients. The study found that the WSI feature-based DLPM showed good predictive performance and combining it with clinical characteristics improved the prediction performance. The study also found that DLPM performed best in predicting the TNBC subtype and achieved the highest prediction performance when combined with clinical characteristics and stromal TILs in the primary and validation cohorts.
Article
Oncology
Zeyu Zhang, Cheng Fang, Yang Zhang, Song Su, Bo Li, Gang Liu, Zhenhua Hu, Jie Tian
Summary: The application of the nano-scale probe IgG-IRDye800CW allows for precise resection of hepatic carcinoma in patients with cirrhosis. Near-infrared window II (NIR-II) fluorescence imaging can detect HCC lesions and provide clear surgical margins, improving surgical precision.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Chemistry, Analytical
Chen Wei, Shenghan Ren, Kaitai Guo, Haihong Hu, Jimin Liang
Summary: In this study, a high-resolution Swin Transformer network (HRSTNet) is proposed for medical image segmentation. The HRSTNet replaces convolutional layers with Transformer blocks and continuously exchanges feature map information with different resolutions. Experimental results demonstrate that the HRSTNet achieves comparable performance with the state-of-the-art Transformer-based U-Net-like architecture on multiple medical image datasets.
Article
Computer Science, Artificial Intelligence
Chen Wei, Chuang Niu, Yiping Tang, Yue Wang, Haihong Hu, Jimin Liang
Summary: This article introduces a neural predictor guided evolutionary algorithm to enhance the exploration ability of neural architecture search (NAS) and designs two types of neural predictors. Experimental results indicate that this method achieves good performance in NAS tasks.
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
(2023)
Article
Neurosciences
Xiaomei Lin, Tianyuyi Feng, Erheng Cui, Yunfei Li, Zhang Qin, Xiaohu Zhao
Summary: This study successfully established a rat model based on the genetic-environmental interaction, which exhibited phenotype characteristics similar to human AD in terms of cognitive function, brain microstructure, and immunohistochemistry. The genetic factor (APP mutation) and the environmental factor (acrolein exposure) accounted for 39.74% and 33.3% of the AD-like phenotypes in the model, respectively.
Article
Neurosciences
Gustavo Guimara Guerrero, Giovanna Bignoto Minhoto, Camilla dos Santos Tiburcio-Machado, Itza Amarisis Ribeiro Pinto, Claudio Antonio Federico, Marcia Carneiro Valera
Summary: The present study evaluated the influence of head and neck radiotherapy on the behavior and body weight gain in Wistar rats. The results demonstrated that different doses of radiation induced depressive behavior in the animals, and that the weight gain tended to be lower in the irradiated groups.
Article
Neurosciences
Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei Wu
Summary: This study reveals the underlying mechanisms of the rapid antidepressant effects of merazin hydrate (MH), which activates CaMKII to promote neuronal activities and proliferation in the hippocampus.
Article
Neurosciences
Kathleen E. Murray, Whitney A. Ratliff, Vedad Delic, Bruce A. Citron
Summary: Gulf War Illness (GWI) is a chronic disorder that affects approximately 30% of Veterans deployed to the Persian Gulf. This study found that exposure to toxicants during the Gulf War resulted in long-term changes in the morphology of dentate granule cells and that treatment with Nrf2 activator could improve neuronal health in the hippocampus.
Article
Neurosciences
Jing Li, Yan Zou, Xiangchuang Kong, Yangming Leng, Fan Yang, Guofeng Zhou, Bo Liu, Wenliang Fan
Summary: This study examines the functional connectivity changes in individuals with sudden sensorineural hearing loss (SSNHL) at the integrity, network, and edge levels. The findings reveal reduced intranetwork connectivity strength and increased internetwork connectivity in SSNHL patients. These alterations are associated with the duration of SSNHL and Tinnitus Handicap Inventory scores. The study provides crucial insights into the neural mechanisms of SSNHL and the brain's network-level responses to sensory loss.
Review
Neurosciences
Didier Majou, Anne-Lise Dermenghem
Summary: In the early stages of SAD, memory impairment is strongly correlated with cortical levels of soluble amyloid-beta peptide oligomers. A beta disrupts glutamatergic synaptic function and leads to cognitive deficits. This article describes the pathogenic mechanisms underlying cerebral amyloidosis, involving amyloid precursor protein synthesis, A beta residue clearance processes, and the role of specific molecules.
Article
Neurosciences
Jing Li, Yi Shan, Xiaojing Zhao, Guixiang Shan, Peng-Hu Wei, Lin Liu, Changming Wang, Hang Wu, Weiqun Song, Yi Tang, Guo-Guang Zhao, Jie Lu
Summary: This study investigates changes in brain anatomical structures and functional network connectivity after chronic complete thoracic spinal cord injury (cctSCI) and their impact on clinical outcomes. The findings reveal alterations in gray matter volume and functional connectivity in specific brain regions, indicating potential therapeutic targets and methods for tracking treatment outcomes.
Article
Neurosciences
Anllely Fernandez, Katherine Corvalan, Octavia Santis, Maxs Mendez-Ruette, Ariel Caviedes, Matias Pizarro, Maria -Teresa Gomez, Luis Federico Batiz, Peter Landgraf, Thilo Kahne, Alejandro Rojas-Fernandez, Ursula Wyneken
Summary: This study reveals the importance of SUMOylation in modulating the protein cargo of astrocyte-derived small extracellular vesicles (sEVs) and its potential impact on neurons.
Article
Neurosciences
Anika Luettig, Stefanie Perl, Maria Zetsche, Franziska Richter, Denise Franz, Marco Heerdegen, Ruediger Koehling, Angelika Richter
Summary: This study found that changes in c-Fos activity during short-term stimulation of the entopeduncular nucleus (EPN) are associated with improvement in dystonia, and also discovered that the cerebellum may be involved in the antidystonic effects.
Article
Neurosciences
Yanlin Tao, Wei Shen, Houyuan Zhou, Zikang Li, Ting Pi, Hui Wu, Hailian Shi, Fei Huang, Xiaojun Wu
Summary: Depression has a higher incidence in women compared to men, and this study investigated the impact of sex on depressive behaviors and underlying mechanisms using a corticosterone-induced depression model in mice. The results showed sex-specific anxiety and depression behaviors in the model group, as well as differences in protein expression and neurotransmitter levels between male and female mice. These findings enhance our understanding of sex-specific differences in depression and support tailored interventions.
Review
Neurosciences
Dnyandev G. Gadhave, Vrashabh V. Sugandhi, Chandrakant R. Kokare
Summary: This article discusses the characteristics and importance of the tight junctions of endothelial cells in the CNS, which act as a biological barrier known as the blood-brain barrier (BBB). It focuses on overcoming the challenges of delivering therapeutic agents to the brain in neurodegenerative disorders, particularly multiple sclerosis, through the use of biomaterials. The article also highlights the current limitations of animal models for studying multiple sclerosis and suggests a potential future research direction.
Article
Neurosciences
Li-Min Mao, Khyathi Thallapureddy, John Q. Wang
Summary: Propofol can enhance synapsin phosphorylation and modulate synaptic transmission in the mouse brain. The study reveals the potential role of synapsin as a substrate of propofol and its effects on neurotransmitter release machinery.
Article
Neurosciences
Syed Maaz Ahmed Rizvi, Abdul Baseer Buriro, Irfan Ahmed, Abdul Aziz Memon
Summary: This study explores the effects of prolonged mask usage on the human brain by analyzing EEG and physiological parameters. The results show that the mean EEG spectral power in alpha, beta, and gamma sub-bands of individuals wearing masks is smaller than those without masks. The performances on cognitive tasks and oxygen saturation level differ between the two groups, while blood pressure, body temperature, and heart rate are similar. The analysis also reveals that the occipital and frontal lobes exhibit the greatest variability in channel measurements.
Article
Neurosciences
Rui-Fang Ma, Lu-Lu Xue, Jin-Xiang Liu, Li Chen, Liu-Lin Xiong, Ting-Hua Wang, Fei Liu
Summary: This study observed changes in brain infarction and blood vessels in rats during neonatal hypoxic ischemic encephalopathy (NHIE) modeling using Transcranial Doppler Ultrasonography (TCD). Longer duration of hypoxia was associated with more severe nerve damage. TCD can dynamically monitor cerebral infarction after NHIE modeling, which may serve as a useful auxiliary method for evaluating animal experimental models.
Article
Neurosciences
Yuxiang Dai, Chen Yu, Lu Zhou, Longyang Cheng, Hongbin Ni, Weibang Liang
Summary: Overexpression of CXCR4 in glioma is correlated with patient survival, and its inhibition can reduce invasion and migration of glioma cells. Inhibiting Nur77 also decreases cancer progression associated with CXCR4.