Article
Neurosciences
Sebastian Scholz, Stephan Dutke, Niko A. Busch
Summary: Results from item-method directed forgetting show that individuals can intentionally forget processed information, possibly through selective rehearsal and inhibitory control. The time taken to process information may also play a role in intentional forgetting mechanisms.
Article
Psychology, Experimental
Klaus Oberauer, Werner Greve
Summary: The intention to remember information substantially improves recall of that information when maintained in working memory, but it does not have the same effect on episodic long-term memory. The differences observed may be attributed to factors such as test delay, list length, and proactive interference.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2021)
Article
Behavioral Sciences
Ryan J. Hubbard, Lili Sahakyan
Summary: Psychological and neuroscientific experiments have shown that people can intentionally forget information through direct suppression and thought substitution. The study found that Forget and Imagine cues can lead to similar forgetting effects, but through different neural processes. Forget cues elicited changes in frontal oscillatory power that predicted future forgetting, while item-cue representational similarity was predictive of later accuracy for Imagine cues.
Review
Psychology, Multidisciplinary
Annette Kluge
Summary: This mini review summarizes the current state-of-the-art of empirical unlearning and intentional forgetting (U/IF) research at different levels. It incorporates 31 recent studies and reveals predictors, process variables, and outcome variables related to U/IF. The study designs vary at different levels, with the individual-level studies using longitudinal designs. However, there is a lack of detailed understanding of the temporal and process-related aspects of U/IF at different levels.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Olga Lucia Gamboa, Hu Chuan-Peng, Christian E. Salas, Kenneth S. L. Yuen
Summary: Intentional forgetting is an important adaptive mechanism that involves the interaction of two networks. A core region is activated regardless of paradigms and sample characteristics, while a secondary network involves frontal-hippocampal interactions. The findings of this study open up new possibilities for the development of effective clinical interventions.
Article
Multidisciplinary Sciences
Kevin van Schie, Jonathan M. Fawcett, Michael C. Anderson
Summary: Suppressing unwanted memories leads to forgetting, often attributed to inhibitory control. This forgetting is cue-independent, but does it necessarily mean that the memory has been inhibited?
SCIENTIFIC REPORTS
(2023)
Article
Psychology, Mathematical
Huiyu Ding, Jonathon Whitlock, Lili Sahakyan
Summary: Through three experiments, researchers used an intentional forgetting procedure to compare the magnitude of intentional forgetting of own-race faces and other-race faces. The results showed that both own-race and other-race faces were equally susceptible to forgetting, regardless of the memory instruction.
PSYCHONOMIC BULLETIN & REVIEW
(2022)
Article
Neurosciences
Alana Muller, Lindsey A. Sirianni, Richard J. Addante
Summary: The Dunning-Kruger effect is a metacognitive phenomenon that has been studied by designing experiments and analyzing EEG and reaction time data. High and low estimators use different cognitive strategies, with high estimators possibly relying more on familiarity and low estimators more on recollection.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Daniel Feuerriegel, Mackenzie Murphy, Alexandra Konski, Vinay Mepani, Jie Sun, Robert Hester, Stefan Bode
Summary: Recent studies have revealed that different confidence levels can lead to varying neural activities during decision formation and after. The frontal ERP component and Pe component are associated with confidence, while the CPP component is influenced by volume conduction.
Article
Psychology, Multidisciplinary
Yifei Li, Connie Qun Guan
Summary: Learning to write involves integrating motor production and visual perception to develop orthographic representations. This study examines the effect of hand movement training on neural correlates for L2 Chinese and L2 English readers. The results show that drawing facilitates visual word recognition in Chinese compared to viewing. These findings suggest that hand movement strengthens neural processing and improves behavioral performance in Chinese character recognition for L2 Chinese learners and English word recognition for L2 English learners. Furthermore, the N170 amplitude during drawing is positively correlated with N400 amplitudes, indicating that early visual word recognition is predictive of later comprehension.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Biological
Mingming Qi, Ru Gai, Heming Gao
Summary: This study investigated the impact of chronic academic stress on the directed forgetting process. The stress group, preparing for a major academic exam, and the control group both performed a forgetting task. Results showed that the stress group reported higher levels of stress, anxiety, and negative affect, with decreased cortisol awakening response compared to the control group. Both groups showed better recognition of items to be remembered, suggesting a directed forgetting effect, but the stress group exhibited poorer recognition of forgotten items and a stronger forgetting effect compared to the control group. These findings suggest that chronic academic stress enhances the intentional memory control process.
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2023)
Article
Behavioral Sciences
Corentin A. Wicht, Michael De Pretto, Michael Mouthon, Lucas Spierer
Summary: This study aimed to examine the effects of expectations on neurocognitive processes. By manipulating the conditions of coffee consumption, the researchers found that the effects of caffeine on attention and inhibitory control may have been overestimated, and caffeine primarily influences cognitive processes and brain areas responsible for attention allocation.
Article
Psychology, Biological
Alexander Berger, Markus Kiefer
Summary: In response time (RT) research, outliers, which significantly deviate from the RT distribution, are typically excluded from analysis based on the assumption that cognitive processing is distorted in outliers. This study used event-related potentials (ERP) to compare cognitive processing in trials with outliers and valid trials in two tasks. Results showed that the late positive complex (P3) associated with response-related processes was reduced in outliers across different methods and tasks. Furthermore, the contingent negative variation (CNV) ERP component was also reduced in outliers as a function of task demands. Therefore, cognitive processing is altered in outliers compared to valid trials, suggesting that the RT outlier distribution should be considered for ERP analysis in combined ERP and RT studies.
Article
Neuroimaging
Astrid Graessner, Caroline Duchow, Emiliano Zaccarella, Angela D. Friederici, Hellmuth Obrig, Gesa Hartwigsen
Summary: This study investigated the electrophysiological dynamics of basic semantic composition in post-stroke individuals with aphasia. The results showed that compared to the control group, individuals with aphasia did not exhibit N400 effects between pseudoword and meaningful phrases, but showed additional P600 effects over frontal electrodes. Furthermore, there was an inverse correlation between the magnitude of the N400 and P600 effects in individuals with aphasia.
NEUROIMAGE-CLINICAL
(2023)
Article
Psychology, Multidisciplinary
Vera Varga, Denes Toth, Kathleen Kay Amora, David Czikora, Valeria Csepe
Summary: In developmental dyslexia, deficits in phonological processing and audiovisual processing are more pronounced than deficits in orthographic processing.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Neurosciences
Gerd T. Waldhauser, Verena Braun, Simon Hanslmayr
JOURNAL OF NEUROSCIENCE
(2016)
Article
Neurosciences
Marcus Paul, Marie-Christin Fellner, Gerd T. Waldhauser, John Paul Minda, Nikolai Axmacher, Boris Suchan, Oliver T. Wolf
JOURNAL OF COGNITIVE NEUROSCIENCE
(2018)
Article
Neurosciences
Gerd T. Waldhauser, Karl-Heinz T. Baeuml, Simon Hanslmayr
Editorial Material
Neurosciences
Nikolai Axmacher, Henrik Kessler, Gerd T. Waldhauser
FRONTIERS IN HUMAN NEUROSCIENCE
(2014)
Article
Neurosciences
Gerd T. Waldhauser, Mikael Johansson, Simon Hanslmayr
JOURNAL OF NEUROSCIENCE
(2012)
Article
Multidisciplinary Sciences
Gerd T. Waldhauser, Martin J. Dahl, Martina Ruf-Leuschner, Veronika Mueller-Bamouh, Maggie Schauer, Nikolai Axmacher, Thomas Elbert, Simon Hanslmayr
SCIENTIFIC REPORTS
(2018)
Article
Neurosciences
Lorika Shkreli, Marcella Lydia Woud, Roger Ramsbottom, Aleksandra Ewa Rupietta, Gerd Thomas Waldhauser, Robert Kumsta, Andrea Reinecke
NEUROPSYCHOPHARMACOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Marie-Christin Fellner, Gerd T. Waldhauser, Nikolai Axmacher
Article
Psychology, Clinical
Anna-Christine Schmidt, Gerd T. Waldhauser, Felicitas Hestermann, Aram Kehyayan, Henrik Kessler, Nikolai Axmacher
Summary: Forgetting is not always passive; it can also be a result of active memory control. Repression, as a psychoanalytic construct, was one of the first conceptualizations of motivated forgetting. However, the concept of repression has different definitions, making a standardized empirical approach challenging. The free association (FA) paradigm, which is consistent with repression as an unconscious process induced by conflicts and maintained by resistance, and the think/no-think (TNT) paradigm, which measures the cognitive aspect of repression known as suppression, are two paradigms used to study memory control. This study investigated the interindividual correlations between memory control in the TNT and the FA paradigms and found no association between the two, suggesting that they measure different processes.
PSYCHOANALYTIC PSYCHOLOGY
(2022)
Article
Psychology, Multidisciplinary
Gerd T. Waldhauser, Mikael Johansson, Martin Backstrom, Axel Mecklinger
SCANDINAVIAN JOURNAL OF PSYCHOLOGY
(2011)
Article
Psychology, Multidisciplinary
Gerd T. Waldhauser, Magnus Lindgren, Mikael Johansson
FRONTIERS IN PSYCHOLOGY
(2012)
Article
Neurosciences
Xiaomei Lin, Tianyuyi Feng, Erheng Cui, Yunfei Li, Zhang Qin, Xiaohu Zhao
Summary: This study successfully established a rat model based on the genetic-environmental interaction, which exhibited phenotype characteristics similar to human AD in terms of cognitive function, brain microstructure, and immunohistochemistry. The genetic factor (APP mutation) and the environmental factor (acrolein exposure) accounted for 39.74% and 33.3% of the AD-like phenotypes in the model, respectively.
Article
Neurosciences
Gustavo Guimara Guerrero, Giovanna Bignoto Minhoto, Camilla dos Santos Tiburcio-Machado, Itza Amarisis Ribeiro Pinto, Claudio Antonio Federico, Marcia Carneiro Valera
Summary: The present study evaluated the influence of head and neck radiotherapy on the behavior and body weight gain in Wistar rats. The results demonstrated that different doses of radiation induced depressive behavior in the animals, and that the weight gain tended to be lower in the irradiated groups.
Article
Neurosciences
Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei Wu
Summary: This study reveals the underlying mechanisms of the rapid antidepressant effects of merazin hydrate (MH), which activates CaMKII to promote neuronal activities and proliferation in the hippocampus.
Article
Neurosciences
Kathleen E. Murray, Whitney A. Ratliff, Vedad Delic, Bruce A. Citron
Summary: Gulf War Illness (GWI) is a chronic disorder that affects approximately 30% of Veterans deployed to the Persian Gulf. This study found that exposure to toxicants during the Gulf War resulted in long-term changes in the morphology of dentate granule cells and that treatment with Nrf2 activator could improve neuronal health in the hippocampus.
Article
Neurosciences
Jing Li, Yan Zou, Xiangchuang Kong, Yangming Leng, Fan Yang, Guofeng Zhou, Bo Liu, Wenliang Fan
Summary: This study examines the functional connectivity changes in individuals with sudden sensorineural hearing loss (SSNHL) at the integrity, network, and edge levels. The findings reveal reduced intranetwork connectivity strength and increased internetwork connectivity in SSNHL patients. These alterations are associated with the duration of SSNHL and Tinnitus Handicap Inventory scores. The study provides crucial insights into the neural mechanisms of SSNHL and the brain's network-level responses to sensory loss.
Review
Neurosciences
Didier Majou, Anne-Lise Dermenghem
Summary: In the early stages of SAD, memory impairment is strongly correlated with cortical levels of soluble amyloid-beta peptide oligomers. A beta disrupts glutamatergic synaptic function and leads to cognitive deficits. This article describes the pathogenic mechanisms underlying cerebral amyloidosis, involving amyloid precursor protein synthesis, A beta residue clearance processes, and the role of specific molecules.
Article
Neurosciences
Jing Li, Yi Shan, Xiaojing Zhao, Guixiang Shan, Peng-Hu Wei, Lin Liu, Changming Wang, Hang Wu, Weiqun Song, Yi Tang, Guo-Guang Zhao, Jie Lu
Summary: This study investigates changes in brain anatomical structures and functional network connectivity after chronic complete thoracic spinal cord injury (cctSCI) and their impact on clinical outcomes. The findings reveal alterations in gray matter volume and functional connectivity in specific brain regions, indicating potential therapeutic targets and methods for tracking treatment outcomes.
Article
Neurosciences
Anllely Fernandez, Katherine Corvalan, Octavia Santis, Maxs Mendez-Ruette, Ariel Caviedes, Matias Pizarro, Maria -Teresa Gomez, Luis Federico Batiz, Peter Landgraf, Thilo Kahne, Alejandro Rojas-Fernandez, Ursula Wyneken
Summary: This study reveals the importance of SUMOylation in modulating the protein cargo of astrocyte-derived small extracellular vesicles (sEVs) and its potential impact on neurons.
Article
Neurosciences
Anika Luettig, Stefanie Perl, Maria Zetsche, Franziska Richter, Denise Franz, Marco Heerdegen, Ruediger Koehling, Angelika Richter
Summary: This study found that changes in c-Fos activity during short-term stimulation of the entopeduncular nucleus (EPN) are associated with improvement in dystonia, and also discovered that the cerebellum may be involved in the antidystonic effects.
Article
Neurosciences
Yanlin Tao, Wei Shen, Houyuan Zhou, Zikang Li, Ting Pi, Hui Wu, Hailian Shi, Fei Huang, Xiaojun Wu
Summary: Depression has a higher incidence in women compared to men, and this study investigated the impact of sex on depressive behaviors and underlying mechanisms using a corticosterone-induced depression model in mice. The results showed sex-specific anxiety and depression behaviors in the model group, as well as differences in protein expression and neurotransmitter levels between male and female mice. These findings enhance our understanding of sex-specific differences in depression and support tailored interventions.
Review
Neurosciences
Dnyandev G. Gadhave, Vrashabh V. Sugandhi, Chandrakant R. Kokare
Summary: This article discusses the characteristics and importance of the tight junctions of endothelial cells in the CNS, which act as a biological barrier known as the blood-brain barrier (BBB). It focuses on overcoming the challenges of delivering therapeutic agents to the brain in neurodegenerative disorders, particularly multiple sclerosis, through the use of biomaterials. The article also highlights the current limitations of animal models for studying multiple sclerosis and suggests a potential future research direction.
Article
Neurosciences
Li-Min Mao, Khyathi Thallapureddy, John Q. Wang
Summary: Propofol can enhance synapsin phosphorylation and modulate synaptic transmission in the mouse brain. The study reveals the potential role of synapsin as a substrate of propofol and its effects on neurotransmitter release machinery.
Article
Neurosciences
Syed Maaz Ahmed Rizvi, Abdul Baseer Buriro, Irfan Ahmed, Abdul Aziz Memon
Summary: This study explores the effects of prolonged mask usage on the human brain by analyzing EEG and physiological parameters. The results show that the mean EEG spectral power in alpha, beta, and gamma sub-bands of individuals wearing masks is smaller than those without masks. The performances on cognitive tasks and oxygen saturation level differ between the two groups, while blood pressure, body temperature, and heart rate are similar. The analysis also reveals that the occipital and frontal lobes exhibit the greatest variability in channel measurements.
Article
Neurosciences
Rui-Fang Ma, Lu-Lu Xue, Jin-Xiang Liu, Li Chen, Liu-Lin Xiong, Ting-Hua Wang, Fei Liu
Summary: This study observed changes in brain infarction and blood vessels in rats during neonatal hypoxic ischemic encephalopathy (NHIE) modeling using Transcranial Doppler Ultrasonography (TCD). Longer duration of hypoxia was associated with more severe nerve damage. TCD can dynamically monitor cerebral infarction after NHIE modeling, which may serve as a useful auxiliary method for evaluating animal experimental models.
Article
Neurosciences
Yuxiang Dai, Chen Yu, Lu Zhou, Longyang Cheng, Hongbin Ni, Weibang Liang
Summary: Overexpression of CXCR4 in glioma is correlated with patient survival, and its inhibition can reduce invasion and migration of glioma cells. Inhibiting Nur77 also decreases cancer progression associated with CXCR4.