Article
Biochemistry & Molecular Biology
Rafael Rodrigues Lima, Ana Carolina Alves Oliveira, Rafael Monteiro Fernandes, Priscila Cunha Nascimento, Marco Aurelio M. Freire, Walace Gomes-Leal
Summary: Stroke, a leading cause of death and disabilities, results in debilitating conditions due to disturbances in cerebral blood vessels. Besides primary metabolic collapse, secondary events like excitotoxicity, inflammatory response, and oxidative stress contribute to additional cell death and functional impairment. This study found that primary ischemic damage in the dorsal striatum can lead to secondary white matter damage in the surrounding corpus callosum in adult rats.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Neurosciences
Natalia Del Campo, Owen Phillips, Francoise Ory-Magne, Christine Brefel-Courbon, Monique Galitzky, Claire Thalamas, Katherine L. Narr, Shantanu Joshi, Manpreet K. Singh, Patrice Peran, Anne Pavy-LeTraon, Olivier Rascol
Summary: Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by widespread accumulation of alpha-synuclein, primarily in oligodendrocytes. Whole brain deep and superficial white matter diffusivity abnormalities were observed in MSA patients but not in Parkinson's disease (PD) patients. These abnormalities were associated with motor and cognitive functions in MSA patients.
HUMAN BRAIN MAPPING
(2021)
Article
Geriatrics & Gerontology
Tsukasa Nagase, Chihiro Tohda
Summary: This study reveals that skeletal muscle atrophy has a negative impact on memory impairment in young 5XFAD mice, likely mediated by the muscle-secreted plasma transporter protein hemopexin.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Clinical Neurology
Min Zhou, Rongwen Li, Poornima Venkat, Yu Qian, Michael Chopp, Alex Zacharek, Julie Landschoot-Ward, Brianna Powell, Quan Jiang, Xu Cui
Summary: This study found that L-4F may provide a restorative strategy for stroke in type 2 diabetes mellitus (T2DM) patients by promoting neurovascular and white matter remodeling. Reducing neuroinflammation in the injured brain may contribute to the restorative effects of L-4F.
FRONTIERS IN NEUROLOGY
(2022)
Article
Psychiatry
AmirHussein Abdolalizadeh, Hamidreza Ostadrahimi, Mohammad Amin Dabbagh Ohadi, Seyed AmirHussein Saneei, Amir Sasan Bayani Ershadi
Summary: The study found a widespread association between the severity of apathy-avolition in schizophrenia patients and white matter microstructural properties, indicating that white matter pathology may play a role in apathy in schizophrenia independent of disease severity. The study also suggests that diffuse neuroinflammatory processes may contribute to apathy-avolition in schizophrenia.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Clinical Neurology
Markus Lauerer, Matthias Bussas, Viola Pongratz, Achim Berthele, Jan S. Kirschke, Benedikt Wiestler, Claus Zimmer, Bernhard Hemmer, Mark Muehlau
Summary: Brain atrophy in multiple sclerosis (MS) is measured by percentage brain volume change (PBVC) from MRI and is an important outcome parameter in clinical trials. In this study of 600 patients with relapsing-remitting MS, multiple regression analysis revealed that PBVC mainly reflects volume loss of white and cortical gray matter, while deep gray matter and white matter lesions have a lesser impact. These findings enhance our understanding of PBVC changes in MS.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2023)
Article
Neurosciences
Ting Xu, Jiao Liu, Xin-rui Li, Yinghua Yu, Xuan Luo, Xian Zheng, Yuan Cheng, Pei-quan Yu, Yi Liu
Summary: Diabetic encephalopathy, characterized by neuroinflammation and aberrant synaptogenesis, involves the mTOR and NF-kappa B signaling pathways. Inhibiting mTOR and NF-kappa B can reduce inflammatory cytokines expression and increase synaptic proteins, leading to the improvement of cognitive decline in diabetic models. This study suggests that targeting the mTOR/NF-kappa B pathway could be a potential therapeutic strategy for treating diabetic encephalopathy and related cognitive impairments.
MOLECULAR NEUROBIOLOGY
(2021)
Article
Endocrinology & Metabolism
Heng Yang, Wei Ni, Pengju Wei, Sicheng Li, Xinjie Gao, Jiabin Su, Hanqiang Jiang, Yu Lei, Liangfu Zhou, Yuxiang Gu
Summary: Inhibition of HDACs can reduce neuroinflammation and white matter damage after ICH by modulating microglia/macrophage polarization, leading to improved neurological functional recovery.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2021)
Article
Psychiatry
Peter Kochunov, Artemis Zavaliangos-Petropulu, Neda Jahanshad, Paul M. Thompson, Meghann C. Ryan, Joshua Chiappelli, Shuo Chen, Xiaoming Du, Kathryn Hatch, Bhim Adhikari, Hemalatha Sampath, Stephanie Hare, Mark Kvarta, Eric Goldwaser, Fude Yang, Rene L. Olvera, Peter T. Fox, Joanne E. Curran, John Blangero, David C. Glahn, Yunlong Tan, L. Elliot Hong
Summary: Schizophrenia (SZ) is associated with an elevated risk of developing Alzheimer's disease (AD), both of which have white matter abnormalities and cognitive deficits. The study found that white matter deficit patterns in SZ patients become more similar to those in AD patients with age, with SZ patients showing higher white matter vulnerability compared to healthy controls. Elevated white matter deficits were also associated with cognitive measures in both SZ and AD patients.
SCHIZOPHRENIA BULLETIN
(2021)
Article
Neurosciences
Wenqiao Fu, Xudong Che, Jiahe Tan, Shizhen Cui, Yinrui Ma, Daiqi Xu, Haibo Long, Xiaolin Yang, Tangmin Wen, Zhaohui He
Summary: Rasd1 plays a modulated role in ferroptosis of oligodendrocytes in white matter injury following SAH. Rasd1 mainly located in neurons after SAH. Rasd1 significantly inhibits UCP2 functions and induces elevated ROS levels. Subsequently, such changes trigger glia activation and oxidative stress and finally result in increasing NCOA4-mediated ferritinophagy in oligodendrocytes and causes ferroptosis. Ferroptosis of oligodendrocytes contributes to white matter injury in EBI following SAH.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Critical Care Medicine
Federico Moro, Ilaria Lisi, Daniele Tolomeo, Gloria Vegliante, Rosaria Pascente, Edoardo Mazzone, Riaz Hussain, Edoardo Micotti, Julian Dallmeier, Francesca Pischiutta, Elisa Bianchi, Roberto Chiesa, Kevin K. Wang, Elisa R. Zanier
Summary: In a mouse model of repeated mild traumatic brain injury (rmTBI), the study investigated the presence of ongoing neuropathology before chronic functional impairment using MRI and plasma biomarkers. The findings suggest that early quantification of plasma neurofilament light (NfL) can be used to monitor the brain's susceptibility to a second mTBI and guide the return to practice in sport-related TBI.
JOURNAL OF NEUROTRAUMA
(2023)
Review
Clinical Neurology
Christopher M. Filley
Summary: White matter dementia (WMD) is a concept that emphasizes the importance of white matter pathology in cognitive dysfunction and dementia. The introduction of magnetic resonance imaging (MRI) has played a crucial role in recognizing WMD. Neuropsychological studies have identified cognitive slowing and executive dysfunction as the main clinical presentation of WMD. White matter pathology is also associated with neurodegenerative diseases and has potential implications for clinical practice, including preventive measures and treatments that focus on white matter restoration and plasticity.
FRONTIERS IN NEUROLOGY
(2022)
Review
Neurosciences
Kai Yang, Zhengqi Wu, Jie Long, Wenxin Li, Xi Wang, Ning Hu, Xinyue Zhao, Taolei Sun
Summary: This article reviews the evidence collected by magnetic resonance imaging (MRI) techniques on the white matter (WM) abnormalities in Parkinson's disease (PD) and discusses the correlations between WM changes and specific PD symptoms. Transcriptome and genome studies are also summarized to show the changes in oligodendrocytes (OLs)/myelin in PD. The authors conclude that WM abnormalities caused by myelin/OLs changes may be important for PD pathology and can be potential targets for PD treatment.
NPJ PARKINSONS DISEASE
(2023)
Review
Clinical Neurology
Peter T. Nelson, Julie A. Schneider, Gregory A. Jicha, Michael Tran Duong, David A. Wolk
Summary: Recent therapeutic advances have increased the need for accurate diagnosis of the underlying causes of dementia. This review emphasizes the clinical recognition of limbic-predominant age-related TDP-43 encephalopathy (LATE), which affects approximately one-quarter of older adults and is often mistaken for Alzheimer's disease (AD). Although AD and LATE can co-occur, they differ in the protein aggregates driving neuropathology. This review discusses the signs, symptoms, diagnostic testing, and potential treatment implications of LATE.
ANNALS OF NEUROLOGY
(2023)
Article
Biochemistry & Molecular Biology
Nicolo Tedone, Paolo Preziosa, Alessandro Meani, Elisabetta Pagani, Carmen Vizzino, Massimo Filippi, Maria A. Rocca
Summary: In this study, the researchers investigated whether the regional distribution of white matter lesions, normal-appearing white matter microstructural abnormalities, and gray matter atrophy contribute differently to cognitive performance in MS patients based on their sex. The study found that in female MS patients, the association between white matter lesions and microstructural abnormalities with cognitive performance, especially global cognition, is stronger. In contrast, male MS patients showed worse performance on verbal memory tasks.
MOLECULAR PSYCHIATRY
(2023)
Article
Agriculture, Dairy & Animal Science
Ammar Mollaei Berenti, Mojtaba Yari, Saeed Khalaji, Mahdi Hedayati, Amin Akbarian, Peiqiang Yu
Summary: The study showed that substituting common soybean meal with extruded soybean meal in dairy calves' diet could improve their growth performance, nutrient digestibility, and blood metabolites, indicating the sensitivity of calves' responses to different protein characteristics.
Review
Food Science & Technology
Maria E. Rodriguez-Espinosa, Victor H. Guevara-Oquendo, Jen-Chieh Yang, Xin Feng, Weixian Zhang, Peiqiang Yu
Summary: This review provides an overview of recent advancements in studying processing induced molecular structure changes in cool-season faba bean using advanced vibrational molecular spectroscopy, chemometrics, and nutrient modeling techniques. It discusses strategies to improve faba bean utilization through heat-related technological treatments and their relationship to nutrient delivery and metabolism in ruminant systems. Additionally, the article highlights the significance of combining advanced nutrient modeling techniques with cutting-edge vibrational molecular spectroscopic techniques to understand the molecular nutrition and structure of cool-season faba bean.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Hangshu Xin, Peiqiang Yu
Summary: Heating treatments with microwave irradiation and moist autoclaving can change the nutrient contents and availability in faba beans. The results showed increased ether extract and neutral detergent insoluble CP contents, and decreased soluble CP, sugar, and tannin concentrations after heating. Despite the improvements in nutrients absorption, heating failed to enhance digestibility in total tract. The thermal treatments had a significant impact on protein structural characteristics and nutrient availability in ruminants.
Review
Food Science & Technology
Ming Yan, Victor H. Guevara-Oquendo, Maria E. Rodriguez-Espinosa, Jen-Chieh Yang, Herbert (Bart) Lardner, David A. Christensen, Xin Feng, Peiqiang Yu
Summary: The study focuses on the limitations of traditional wet chemistry analysis in studying plant cell wall complexity and the advantages of using synchrotron-based and globar-sourced mid-infrared spectroscopy to analyze chemical bonds. It emphasizes the importance of applying advanced spectroscopy techniques in studying the nutritional characteristics of faba beans.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Agriculture, Dairy & Animal Science
Siqiang Liu, Ali Mujtaba Shah, Mei Yuan, Kun Kang, Zhisheng Wang, Lizhi Wang, Bai Xue, Huawei Zou, Xiangfei Zhang, Peiqiang Yu, Hongze Wang, Gang Tian, Quanhui Peng
Summary: This study found that supplementing ADY can increase the average daily gain of beef cattle and increase the concentration of propionic acid in the rumen. The high plane of nutrition group had higher digestibility rates for neutral detergent fiber and acid detergent fiber, while the relative abundance of Firmicutes and Ruminococcaceae UCG-002 was higher in the ADY4 group.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Hangshu Xin, Nazir Ahmad Khan, Peiqiang Yu
Summary: Recently, new lines of Brassica carinata with high oil and erucic acid contents in their seeds have been developed for the bio-fuel industry. The effects of steam pressure heating on the molecular structures, nutritional and metabolic characteristics of carinata meal produced from these new lines have not been investigated. Steam pressure heating altered carbohydrate chemical components and CNCPS subfractions, leading to changes in ruminal fermentation characteristics and gas production.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
V. H. Guevara-Oquendo, M. E. Rodriguez Espinosa, Peiqiang Yu
Summary: This study aimed to develop and test eight blend pelleted products (BPPs) for ruminants based on a new co-product (CR, carinata meal) and conventional co-product (CN, canola meal). The results showed that the CR-based products had higher true nutritive values and lower glucosinolates and condensed tannins compared to CN-based products.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Review
Food Science & Technology
M. R. Tosta, L. L. Prates, X. Feng, M. E. Rodriguez-Espinosa, H. Zhang, W. Zhang, Peiqiang Yu
Summary: This study focuses on the production, nutrition, and technological processing impact of cool-season adapted oat and barley cereal kernels. By utilizing vibrational molecular spectroscopy, the study provides a potential approach to understand the molecular structure and molecular nutrition interaction of grains.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Spectroscopy
Yajing Ban, Luciana L. Prates, Xin Feng, Nazir A. Khan, Peiqiang Yu
Summary: The study utilized advanced synchrotron radiation technique-SR-FT/vIMS to detect chemical profiles related to protein and carbohydrate biopolymers, and quantify nutrient utilization of newly developed carinata and canola seed lines. Molecular spectral analysis showed structural differences between the seeds, but similarities in protein and carbohydrate structure when not using spectral parameterization. This information can be used to predict protein degradation kinetics and nutrient supply for dairy cows.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Agriculture, Dairy & Animal Science
Hojjat Gholizadeh, Abbas A. Naserian, Mojtaba Yari, Arjan Jonker, Peiqiang Yu
Summary: The study aimed to determine protein characteristics in different barley, corn, and sorghum cultivars, focusing on protein subfractionation and in situ ruminal protein degradability. Barley showed superior characteristics in terms of protein degradation rate and extent compared to corn and sorghum, with different FTIR protein molecular structures.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Review
Food Science & Technology
Victor H. Guevara Oquendo, Maria E. Rodriguez Espinosa, Peiqiang Yu
Summary: The article reviews recent research progress on faba bean seeds and plants in food and feed, focusing on their chemical, nutritional, and molecular characteristics analyzed with molecular spectroscopy. It also discusses the potential applications of molecular spectroscopy in studying molecular chemistry and nutrition interaction in faba beans, offering insights for future research directions.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Food Science & Technology
Ranithri Abeynayake, Sitian Zhang, Wenzhu Yang, Lingyun Chen
Summary: This study demonstrates the potential to use brewers' spent grain as a cost-effective raw material to produce natural antioxidants for food applications.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Murillo Ceola Stefano Pereira, Karen A. Beauchemin, Tim A. McAllister, Wenzhu Z. Yang, Katharine M. Wood, Gregory Brent Penner
Summary: Providing physically effective neutral detergent fiber (peNDF), based on forages greater than 4-mm, has a greater effect on rumination time, ruminal fermentation, and ruminal motility compared to measuring undigested neutral detergent fiber (uNDF) alone. However, uNDF alone affects feeding behavior and reduces digestibility. Characterization of peNDF and uNDF can be useful in formulating finishing diets for cattle. Rating: 9/10
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Murillo Ceola Stefano Pereira, Wenzhu Z. Yang, Karen A. Beauchemin, Timothy A. McAllister, Katharine M. Wood, Gregory B. Penner
Summary: This study evaluated the effects of forages (BarS vs. STR) that differ in the uNDF concentration and FI rate on ruminal fermentation, total tract barrier function, reticulo-ruminal motility, and blood metabolites of beef heifers. The results showed that the forage type and FI rate act independently. Providing forages with greater dietary uNDF can stimulate the frequency of reticulo-ruminal contractions and reduce gastrointestinal permeability with no effect on ruminal pH. Increasing the FI rate stabilized ruminal pH, increased rumination time, stimulated reticulo-ruminal contractions, and decreased indicators of systemic inflammation.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Neurosciences
Xiaomei Lin, Tianyuyi Feng, Erheng Cui, Yunfei Li, Zhang Qin, Xiaohu Zhao
Summary: This study successfully established a rat model based on the genetic-environmental interaction, which exhibited phenotype characteristics similar to human AD in terms of cognitive function, brain microstructure, and immunohistochemistry. The genetic factor (APP mutation) and the environmental factor (acrolein exposure) accounted for 39.74% and 33.3% of the AD-like phenotypes in the model, respectively.
Article
Neurosciences
Gustavo Guimara Guerrero, Giovanna Bignoto Minhoto, Camilla dos Santos Tiburcio-Machado, Itza Amarisis Ribeiro Pinto, Claudio Antonio Federico, Marcia Carneiro Valera
Summary: The present study evaluated the influence of head and neck radiotherapy on the behavior and body weight gain in Wistar rats. The results demonstrated that different doses of radiation induced depressive behavior in the animals, and that the weight gain tended to be lower in the irradiated groups.
Article
Neurosciences
Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei Wu
Summary: This study reveals the underlying mechanisms of the rapid antidepressant effects of merazin hydrate (MH), which activates CaMKII to promote neuronal activities and proliferation in the hippocampus.
Article
Neurosciences
Kathleen E. Murray, Whitney A. Ratliff, Vedad Delic, Bruce A. Citron
Summary: Gulf War Illness (GWI) is a chronic disorder that affects approximately 30% of Veterans deployed to the Persian Gulf. This study found that exposure to toxicants during the Gulf War resulted in long-term changes in the morphology of dentate granule cells and that treatment with Nrf2 activator could improve neuronal health in the hippocampus.
Article
Neurosciences
Jing Li, Yan Zou, Xiangchuang Kong, Yangming Leng, Fan Yang, Guofeng Zhou, Bo Liu, Wenliang Fan
Summary: This study examines the functional connectivity changes in individuals with sudden sensorineural hearing loss (SSNHL) at the integrity, network, and edge levels. The findings reveal reduced intranetwork connectivity strength and increased internetwork connectivity in SSNHL patients. These alterations are associated with the duration of SSNHL and Tinnitus Handicap Inventory scores. The study provides crucial insights into the neural mechanisms of SSNHL and the brain's network-level responses to sensory loss.
Review
Neurosciences
Didier Majou, Anne-Lise Dermenghem
Summary: In the early stages of SAD, memory impairment is strongly correlated with cortical levels of soluble amyloid-beta peptide oligomers. A beta disrupts glutamatergic synaptic function and leads to cognitive deficits. This article describes the pathogenic mechanisms underlying cerebral amyloidosis, involving amyloid precursor protein synthesis, A beta residue clearance processes, and the role of specific molecules.
Article
Neurosciences
Jing Li, Yi Shan, Xiaojing Zhao, Guixiang Shan, Peng-Hu Wei, Lin Liu, Changming Wang, Hang Wu, Weiqun Song, Yi Tang, Guo-Guang Zhao, Jie Lu
Summary: This study investigates changes in brain anatomical structures and functional network connectivity after chronic complete thoracic spinal cord injury (cctSCI) and their impact on clinical outcomes. The findings reveal alterations in gray matter volume and functional connectivity in specific brain regions, indicating potential therapeutic targets and methods for tracking treatment outcomes.
Article
Neurosciences
Anllely Fernandez, Katherine Corvalan, Octavia Santis, Maxs Mendez-Ruette, Ariel Caviedes, Matias Pizarro, Maria -Teresa Gomez, Luis Federico Batiz, Peter Landgraf, Thilo Kahne, Alejandro Rojas-Fernandez, Ursula Wyneken
Summary: This study reveals the importance of SUMOylation in modulating the protein cargo of astrocyte-derived small extracellular vesicles (sEVs) and its potential impact on neurons.
Article
Neurosciences
Anika Luettig, Stefanie Perl, Maria Zetsche, Franziska Richter, Denise Franz, Marco Heerdegen, Ruediger Koehling, Angelika Richter
Summary: This study found that changes in c-Fos activity during short-term stimulation of the entopeduncular nucleus (EPN) are associated with improvement in dystonia, and also discovered that the cerebellum may be involved in the antidystonic effects.
Article
Neurosciences
Yanlin Tao, Wei Shen, Houyuan Zhou, Zikang Li, Ting Pi, Hui Wu, Hailian Shi, Fei Huang, Xiaojun Wu
Summary: Depression has a higher incidence in women compared to men, and this study investigated the impact of sex on depressive behaviors and underlying mechanisms using a corticosterone-induced depression model in mice. The results showed sex-specific anxiety and depression behaviors in the model group, as well as differences in protein expression and neurotransmitter levels between male and female mice. These findings enhance our understanding of sex-specific differences in depression and support tailored interventions.
Review
Neurosciences
Dnyandev G. Gadhave, Vrashabh V. Sugandhi, Chandrakant R. Kokare
Summary: This article discusses the characteristics and importance of the tight junctions of endothelial cells in the CNS, which act as a biological barrier known as the blood-brain barrier (BBB). It focuses on overcoming the challenges of delivering therapeutic agents to the brain in neurodegenerative disorders, particularly multiple sclerosis, through the use of biomaterials. The article also highlights the current limitations of animal models for studying multiple sclerosis and suggests a potential future research direction.
Article
Neurosciences
Li-Min Mao, Khyathi Thallapureddy, John Q. Wang
Summary: Propofol can enhance synapsin phosphorylation and modulate synaptic transmission in the mouse brain. The study reveals the potential role of synapsin as a substrate of propofol and its effects on neurotransmitter release machinery.
Article
Neurosciences
Syed Maaz Ahmed Rizvi, Abdul Baseer Buriro, Irfan Ahmed, Abdul Aziz Memon
Summary: This study explores the effects of prolonged mask usage on the human brain by analyzing EEG and physiological parameters. The results show that the mean EEG spectral power in alpha, beta, and gamma sub-bands of individuals wearing masks is smaller than those without masks. The performances on cognitive tasks and oxygen saturation level differ between the two groups, while blood pressure, body temperature, and heart rate are similar. The analysis also reveals that the occipital and frontal lobes exhibit the greatest variability in channel measurements.
Article
Neurosciences
Rui-Fang Ma, Lu-Lu Xue, Jin-Xiang Liu, Li Chen, Liu-Lin Xiong, Ting-Hua Wang, Fei Liu
Summary: This study observed changes in brain infarction and blood vessels in rats during neonatal hypoxic ischemic encephalopathy (NHIE) modeling using Transcranial Doppler Ultrasonography (TCD). Longer duration of hypoxia was associated with more severe nerve damage. TCD can dynamically monitor cerebral infarction after NHIE modeling, which may serve as a useful auxiliary method for evaluating animal experimental models.
Article
Neurosciences
Yuxiang Dai, Chen Yu, Lu Zhou, Longyang Cheng, Hongbin Ni, Weibang Liang
Summary: Overexpression of CXCR4 in glioma is correlated with patient survival, and its inhibition can reduce invasion and migration of glioma cells. Inhibiting Nur77 also decreases cancer progression associated with CXCR4.
