Geniposide Ameliorates Learning Memory Deficits, Reduces Tau Phosphorylation and Decreases Apoptosis via GSK3β Pathway in Streptozotocin-Induced Alzheimer Rat Model

Chronic Treatment with the GLP1 Analogue Liraglutide Increases Cell Proliferation and Differentiation into Neurons in an AD Mouse Model

(2013) Vadivel Parthsarathy et al.   PLoS One

Metabolic Alterations Induced by Sucrose Intake and Alzheimer’s Disease Promote Similar Brain Mitochondrial Abnormalities

(2012) Cristina Carvalho et al.   DIABETES

Economic Evaluation of Treatment Options in Patients with Alzheimerʼs Disease

(2012) Laura Pouryamout et al.   DRUGS

GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease

(2012) Chong Gao et al.   REVIEWS IN THE NEUROSCIENCES

Glucagon-like peptide 1 receptor plays an essential role in geniposide attenuating lipotoxicity-induced β-cell apoptosis

(2012) Jianhui Liu et al.   TOXICOLOGY IN VITRO

Advances in the Pathogenesis of Alzheimer’s Disease: Focusing on Tau-Mediated Neurodegeneration

(2012) Yale Duan et al.   Translational Neurodegeneration

Diabetes as a risk factor for Alzheimer's disease: insulin signalling impairment in the brain as an alternative model of Alzheimer's disease

(2011) Christian Hölscher   BIOCHEMICAL SOCIETY TRANSACTIONS

Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model

(2011) Teresa Ponce-Lopez et al.   BRAIN RESEARCH

(Val8) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains

(2011) Lin Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Insulin receptor signaling in rat hippocampus: A study in STZ (ICV) induced memory deficit model

(2011) Rahul Agrawal et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs

(2011) Parvathi Rudrabhatla et al.   FASEB JOURNAL

Neuroprotective Effect of Cyclooxygenase Inhibitors in ICV-STZ Induced Sporadic Alzheimer’s Disease in Rats

(2011) Dinesh Kumar Dhull et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease

(2011) P. L. McClean et al.   JOURNAL OF NEUROSCIENCE

Tau Mediated Neurodegeneration: An Insight into Alzheimer’s Disease Pathology

(2011) M. Obulesu et al.   NEUROCHEMICAL RESEARCH

Next-Generation GLP-1 Therapy: An Introduction to Liraglutide

(2011) Thomas Repas   POSTGRADUATE MEDICINE

Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?

(2010) Kawser Akter et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Insulin-resistant brain state (IRBS) changes membrane composition of fatty acids in temporal and entorhinal brain cortices of rats: relevance to sporadic Alzheimer’s disease?

(2010) Konstanze Plaschke et al.   JOURNAL OF NEURAL TRANSMISSION

Anti-apoptotic PI3K/Akt signaling by sodium/glucose transporter 1 reduces epithelial barrier damage and bacterial translocation in intestinal ischemia

(2010) Ching-Ying Huang et al.   LABORATORY INVESTIGATION

Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: involvement of PI3 kinase signal pathway

(2009) Jian-hui Liu et al.   ACTA PHARMACOLOGICA SINICA

GSK3 Inhibitors and Disease

(2009) Felix Hernandez et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Curcumin ameliorates impaired insulin/IGF signalling and memory deficit in a streptozotocin-treated rat model

(2008) Ahmet Turan Isik et al.   AGE

Metabolism and pharmacokinetics of genipin and geniposide in rats

(2008) Y.C. Hou et al.   FOOD AND CHEMICAL TOXICOLOGY

GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals

(2008) Shuxin Hu et al.   NEUROBIOLOGY OF DISEASE