期刊
BRAIN & DEVELOPMENT
卷 34, 期 10, 页码 806-811出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.braindev.2012.02.013
关键词
Attention deficit hyperactivity disorder (ADHD); Integrated visual and auditory continuous performance test (IVA-CPT); Children; EEG; Visual cognitive function
资金
- Child Development Behavioral Research Center, Harbin Medical University
- NSFC [30571576]
- Grants-in-Aid for Scientific Research [23650223] Funding Source: KAKEN
Using visual and auditory continuous performance tests (CPT) and EEG, cognitive function and EEG power were investigated in patients with attention deficit hyperactivity disorder (ADHD). CPT and EEG were conducted for 44 ADHD children and 44 healthy controls of comparable age and sex. The EEG power tests include relative power of theta, alpha, and beta, and theta/beta and theta/alpha ratios. ADHD patients showed significantly higher theta relative power, lower beta relative power, and higher theta/beta ratio (p < 0.05). ADHD patients showed a significantly lower score of auditory CPT (p < 0.05). The EEG power characteristics were correlated significantly with the visual attention function in ADHD children (p < 0.01). Higher-order level cognitive dysfunction affects ADHD pathogenesis. Cortical hypoarousal effects on several mechanisms including the fronto-striatal circuitry may be implicated in the inhibition of prepotent and premature responses. (C) 2012 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.
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