Convergence of pathology in dementia with Lewy bodies and Alzheimer’s disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease

 -Synuclein Is Localized to Mitochondria-Associated ER Membranes

(2014) C. Guardia-Laguarta et al.   JOURNAL OF NEUROSCIENCE

Oxidative stress response elicited by mitochondrial dysfunction: Implication in the pathophysiology of aging

(2013) Chih-Hao Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress

(2013) Eleni N. Tsakiri et al.   FASEB JOURNAL

Stress proteins in aging and life span

(2013) Ayesha Murshid et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

α-Synuclein Membrane Association Is Regulated by the Rab3a Recycling Machinery and Presynaptic Activity

(2013) Robert H. C. Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solid-State 13C NMR Reveals Annealing of Raft-Like Membranes Containing Cholesterol by the Intrinsically Disordered Protein α-Synuclein

(2013) Avigdor Leftin et al.   JOURNAL OF MOLECULAR BIOLOGY

Oxidative stress and mitochondrial protein quality control in aging

(2013) Eirini Lionaki et al.   Journal of Proteomics

Neuropathology of dementia in a large cohort of patients with Parkinson's disease

(2013) Judit Horvath et al.   PARKINSONISM & RELATED DISORDERS

Large  -synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

(2013) B.-K. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer’s disease

(2012) Lara Wahlster et al.   ACTA NEUROPATHOLOGICA

Soluble  -Synuclein Is a Novel Modulator of Alzheimer's Disease Pathophysiology

(2012) M. E. Larson et al.   JOURNAL OF NEUROSCIENCE

 -Synuclein Inhibits Intersynaptic Vesicle Mobility and Maintains Recycling-Pool Homeostasis

(2012) D. Scott et al.   JOURNAL OF NEUROSCIENCE

Familial Aggregation of Dementia With Lewy Bodies

(2011) Angela Nervi et al.   ARCHIVES OF NEUROLOGY

α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding

(2011) Iwona M. Pranke et al.   JOURNAL OF CELL BIOLOGY

DLB and PDD: a role for mutations in dementia and Parkinson disease genes?

(2011) Bram Meeus et al.   NEUROBIOLOGY OF AGING

ReCLIP (Reversible Cross-Link Immuno-Precipitation): An Efficient Method for Interrogation of Labile Protein Complexes

(2011) Andrew L. Smith et al.   PLoS One

Autophagy impairment stimulates PS1 expression and γ-secretase activity

(2010) Kazunori Ohta et al.   Autophagy

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

The First N-terminal Amino Acids of α-Synuclein Are Essential for α-Helical Structure Formation In Vitro and Membrane Binding in Yeast

(2009) Katherina Vamvaca et al.   JOURNAL OF MOLECULAR BIOLOGY

Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy

(2009) Christina R. Bodner et al.   JOURNAL OF MOLECULAR BIOLOGY

Brain-Permeable Small-Molecule Inhibitors of Hsp90 Prevent  -Synuclein Oligomer Formation and Rescue  -Synuclein-Induced Toxicity

(2009) P. Putcha et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production

(2008) Kim N. Green et al.   JOURNAL OF GENERAL PHYSIOLOGY

Formation of Toxic Oligomeric α-Synuclein Species in Living Cells

(2008) Tiago Fleming Outeiro et al.   PLoS One