Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy

Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

(2012) Elena Galea et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy

(2012) Jone López-Erauskin et al.   BRAIN

Very long-chain fatty acids: elongation, physiology and related disorders

(2012) A. Kihara   JOURNAL OF BIOCHEMISTRY

Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibroblasts by inhibiting fatty acid elongation

(2012) Marc Engelen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Induction of Mitochondrial Changes Associated with Oxidative Stress on Very Long Chain Fatty Acids (C22:0, C24:0, or C26:0)-Treated Human Neuronal Cells (SK-NB-E)

(2012) Amira Zarrouk et al.   Oxidative Medicine and Cellular Longevity

Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy

(2011) Jone López-Erauskin et al.   ANNALS OF NEUROLOGY

Oxidative Damage Compromises Energy Metabolism in the Axonal Degeneration Mouse Model of X-Adrenoleukodystrophy

(2011) Jorge Galino et al.   ANTIOXIDANTS & REDOX SIGNALING

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

(2011) Joo-Ho Shin et al.   CELL

Functional genomic analysis unravels a metabolic-inflammatory interplay in adrenoleukodystrophy

(2011) Agatha Schlüter et al.   HUMAN MOLECULAR GENETICS

Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer’s disease

(2011) Hans Lassmann   JOURNAL OF NEURAL TRANSMISSION

Quality assessment of human mitochondrial DNA quantification: MITONAUTS, an international multicentre survey

(2011) Hélène C.F. Côté et al.   MITOCHONDRION

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

(2011) Wei Zhao et al.   Molecular Neurodegeneration

Pathomechanisms Underlying X-Adrenoleukodystrophy: A Three-Hit Hypothesis

(2010) Inderjit Singh et al.   BRAIN PATHOLOGY

General Aspects and Neuropathology of X-Linked Adrenoleukodystrophy

(2010) Isidro Ferrer et al.   BRAIN PATHOLOGY

Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy

(2010) Stéphane Fourcade et al.   HUMAN MOLECULAR GENETICS

Insulin-like growth factor-1 and neurotrophin-3 gene therapy prevents motor decline in an X-linked adrenoleukodystrophy mouse model

(2009) Roberto Mastroeni et al.   ANNALS OF NEUROLOGY

PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

(2009) Weiping Qin et al.   ARCHIVES OF NEUROLOGY

Mitochondrial dysfunction in amyotrophic lateral sclerosis

(2009) Ping Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

Protein Targets of Oxidative Damage in Human Neurodegenerative Diseases with Abnormal Protein Aggregates

(2009) Anna Martínez et al.   BRAIN PATHOLOGY

Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARγ pathway as a therapeutic target in Friedreich’s ataxia

(2009) Giovanni Coppola et al.   HUMAN MOLECULAR GENETICS

Clinical and molecular features of mitochondrial DNA depletion syndromes

(2009) A. Spinazzola et al.   JOURNAL OF INHERITED METABOLIC DISEASE

PPARγ stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss

(2009) Gianluca Miglio et al.   NEUROCHEMISTRY INTERNATIONAL

Effect of Pioglitazone on Sciatic Nerve Ischemia/Reperfusion Injury in Rats

(2009) Reza Rahimian et al.   PEDIATRIC NEUROSURGERY

A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis

(2008) Stéphane Fourcade et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters

(2008) Carlo W. T. van Roermund et al.   FASEB JOURNAL

Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy

(2008) S. Fourcade et al.   HUMAN MOLECULAR GENETICS

Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor   Agonist

(2008) N. Nicolakakis et al.   JOURNAL OF NEUROSCIENCE