Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice

Continuous neurogenesis in the adult brain

(2010) Itaru Imayoshi et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

(2010) Kiran Bhaskar et al.   NEURON

Chronic cerebral hypoperfusion in a mouse model of Alzheimer's disease: An additional contributing factor of cognitive impairment

(2010) Jin Soo Lee et al.   NEUROSCIENCE LETTERS

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

(2009) Richard Killick et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice

(2009) Ehud Cohen et al.   CELL

Neuronal IGF-1 resistance reduces Aβ accumulation and protects against premature death in a model of Alzheimer’s disease

(2009) Susanna Freude et al.   FASEB JOURNAL

Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease

(2009) Sebastian Mirochnic et al.   HIPPOCAMPUS

Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders

(2009) Rommy von Bernhardi et al.   JOURNAL OF NEUROCHEMISTRY

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

(2009) S. Jessberger et al.   LEARNING & MEMORY

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia

(2009) Stefan A Grathwohl et al.   NATURE NEUROSCIENCE

Reorganization of Inhibitory Synapses and Increased PSD Length of Perforated Excitatory Synapses in Hippocampal Area CA1 of Dystrophin-Deficient mdx Mice

(2008) R. Miranda et al.   CEREBRAL CORTEX

Mitochondrial DNA, base excision repair and neurodegeneration

(2008) Nadja C. de Souza-Pinto et al.   DNA REPAIR

Accumulation of nuclear DNA damage or neuron loss: Molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases

(2008) Ivona Brasnjevic et al.   DNA REPAIR

Determining the influence of telomere dysfunction and DNA damage on stem and progenitor cell aging – what markers can we use?

(2008) Kodandaramireddy Nalapareddy et al.   EXPERIMENTAL GERONTOLOGY

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

(2008) Stefanie Frank et al.   GLIA

Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system

(2008) Ryan N. Dilger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Imaging Microglial Activation During Neuroinflammation and Alzheimer’s Disease

(2008) Sriram Venneti et al.   Journal of Neuroimmune Pharmacology

Rapid Microglial Response Around Amyloid Pathology after Systemic Anti-A  Antibody Administration in PDAPP Mice

(2008) J. Koenigsknecht-Talboo et al.   JOURNAL OF NEUROSCIENCE

Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease

(2008) Philip Thomas et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Neuroinflammation Associated with Aging Sensitizes the Brain to the Effects of Infection or Stress

(2008) Nathan L. Sparkman et al.   NEUROIMMUNOMODULATION

Adult neurogenesis is functionally associated with AD-like neurodegeneration

(2007) Qian Chen et al.   NEUROBIOLOGY OF DISEASE