Downregulation of apoptosis-inducing factor in Harlequin mice induces progressive and severe optic atrophy which is durably prevented by AAV2-AIF1 gene therapy
出版年份 2011 全文链接
标题
Downregulation of apoptosis-inducing factor in Harlequin mice induces progressive and severe optic atrophy which is durably prevented by AAV2-AIF1 gene therapy
作者
关键词
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出版物
BRAIN
Volume 135, Issue 1, Pages 35-52
出版商
Oxford University Press (OUP)
发表日期
2011-11-27
DOI
10.1093/brain/awr290
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- (2011) R. T. Ibad et al. JOURNAL OF NEUROSCIENCE
- Severe X-Linked Mitochondrial Encephalomyopathy Associated with a Mutation in Apoptosis-Inducing Factor
- (2010) Daniele Ghezzi et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2
- (2010) E Hangen et al. CELL DEATH AND DIFFERENTIATION
- Pathophysiology of human glaucomatous optic nerve damage: Insights from rodent models of glaucoma
- (2010) John C. Morrison et al. EXPERIMENTAL EYE RESEARCH
- Metabolic Vulnerability Disposes Retinal Ganglion Cell Axons to Dysfunction in a Model of Glaucomatous Degeneration
- (2010) S. Baltan et al. JOURNAL OF NEUROSCIENCE
- Successful Amelioration of Mitochondrial Optic Neuropathy Using the Yeast NDI1 Gene in a Rat Animal Model
- (2010) Mathieu Marella et al. PLoS One
- Leber congenital amaurosis due to RPE65 mutations and its treatment with gene therapy
- (2010) Artur V. Cideciyan PROGRESS IN RETINAL AND EYE RESEARCH
- Mitochondrial optic neuropathies – Disease mechanisms and therapeutic strategies
- (2010) Patrick Yu-Wai-Man et al. PROGRESS IN RETINAL AND EYE RESEARCH
- The Neuro-ophthalmology of Mitochondrial Disease
- (2010) J. Alexander Fraser et al. SURVEY OF OPHTHALMOLOGY
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- (2010) Eric A. Schon et al. TRENDS IN MOLECULAR MEDICINE
- Changes of Mitochondria and Relocation of the Apoptosis-Inducing Factor during Apoptosis
- (2009) A. Ivana Scovassi et al. Annals of the New York Academy of Sciences
- Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders
- (2009) Valerio Carelli et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Intravitreal NGF administration counteracts retina degeneration after permanent carotid artery occlusion in rat
- (2009) Sandra Sivilia et al. BMC NEUROSCIENCE
- Detection of early neuron degeneration and accompanying glial responses in the visual pathway in a rat model of acute intraocular hypertension
- (2009) ShaoDan Zhang et al. BRAIN RESEARCH
- Treatment of mitochondrial electron transport chain disorders: A review of clinical trials over the past decade
- (2009) Douglas S. Kerr MOLECULAR GENETICS AND METABOLISM
- Inner Limiting Membrane Barriers to AAV-mediated Retinal Transduction From the Vitreous
- (2009) Deniz Dalkara et al. MOLECULAR THERAPY
- Distinct Roles of Transcription Factors Brn3a and Brn3b in Controlling the Development, Morphology, and Function of Retinal Ganglion Cells
- (2009) Tudor C. Badea et al. NEURON
- Optimized Allotopic Expression of the Human Mitochondrial ND4 Prevents Blindness in a Rat Model of Mitochondrial Dysfunction
- (2008) Sami Ellouze et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection
- (2008) M Hellström et al. GENE THERAPY
- Inherited mitochondrial optic neuropathies
- (2008) P Yu-Wai-Man et al. JOURNAL OF MEDICAL GENETICS
- Retinal Ganglion Cells Downregulate Gene Expression and Lose Their Axons within the Optic Nerve Head in a Mouse Glaucoma Model
- (2008) I. Soto et al. JOURNAL OF NEUROSCIENCE
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
- (2008) Albert M. Maguire et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2008) James W.B. Bainbridge et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes
- (2008) Paule Bénit et al. PLoS One
- Ocular gene therapy: current progress and future prospects
- (2008) Pasqualina Colella et al. TRENDS IN MOLECULAR MEDICINE
- Prevalence of mitochondrial DNA disease in adults
- (2007) Andrew M. Schaefer et al. ANNALS OF NEUROLOGY
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