期刊
BONE MARROW TRANSPLANTATION
卷 48, 期 -, 页码 S1-S37出版社
SPRINGERNATURE
DOI: 10.1038/bmt.2012.282
关键词
statistical methods; survival analysis; competing risks; statistical guidelines; stem cell transplantation research
资金
- European Group for Blood and Marrow Transplantation (EBMT)
- Tor Vergata University of Rome
This document explains some of the relevant methodological issues involved in planning a clinical study using survival and time-to-event outcome data, particularly in the field of haematopoietic stem cell transplantation, and indicates the appropriate statistical methods to use for the analysis. As the majority of these methods are commonly used in survival and event-history analysis, this document discusses their potential and limitations with reference to common SCT research situations. Some reference is given to methods, recently appearing in the literature that may be capable of handling complex investigations. These guidelines also address various practical issues, such as recoding or transforming variables in regression models or reporting results. Bone Marrow Transplantation (2013) 48, S1-S37; doi:10.1038/bmt.2012.282
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