Review
Microbiology
Virginie Gazil, Octave Nadile Bandiaky, Emmanuelle Renard, Katia Idiri, Xavier Struillou, Assem Soueidan
Summary: The success rates of dental implants at 5 and 10 years are nearly 90%. The prevalence of peri-implant diseases, such as peri-implantitis and peri-implant mucositis, is significant. Recent studies using new generation sequencing methods have compared the microbiota of healthy and diseased periodontal and peri-implant sites, revealing distinct differences in diversity and composition. Understanding the characteristics of the peri-implant microbiota can optimize therapeutic strategies for peri-implant diseases.
Review
Biotechnology & Applied Microbiology
Magda Aline Nagasawa, Marcio de Carvalho Formiga, Vittorio Moraschini, Martinna Bertolini, Joao Gabriel Silva Souza, Magda Feres, Luciene C. Figueiredo, Jamil Awad Shibli
Summary: This systematic review evaluated the features of the progression of experimentally induced gingivitis and peri-implant mucositis in humans. It found that peri-implant mucositis had a more exacerbated clinical response than gingivitis. Additionally, dental implants accumulated less biofilm but had more heterogeneous alterations in the microbiota.
Review
Endocrinology & Metabolism
H. Arbildo-Vega, S. Panda, A. Bal, R. Mohanty, A. Rendon-Alvarado, A. C. Das, F. H. Cruzado-Oliva, E. D. Infantes-Ruiz, B. Manfredi, H. Vasquez-Rodrigo, C. Mortellaro, M. S. Giacomello, M. Parrini, A. Greco Lucchina, M. Del Fabbro
Summary: The study found that the use of probiotics containing Lactobacillus reuteri can be clinically effective in reducing pocket depth in the treatment of peri-implant diseases based on a systematic review and meta-analysis of randomized controlled clinical trials.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2021)
Review
Dentistry, Oral Surgery & Medicine
Marziyeh Shafizadeh, Reza Amid, Masoumeh Mahmoum, Mahdi Kadkhodazadeh
Summary: The systematic review found that inflammatory elements in peri-implantitis (PI) showed significantly increased vascularization and inflammatory cell counts dominated by plasma cells compared with healthy peri-implant tissues (HI). Studies also reported more severe inflammatory infiltrates in PI compared with chronic periodontitis. The meta-analysis results showed a significantly larger surface area of the infiltrated connective tissue in PI.
ARCHIVES OF ORAL BIOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Davide Farronato, Lorenzo Azzi, Luca Giboli, Vittorio Maurino, Gianluca Martino Tartaglia, Marco Farronato
Summary: Smoking may significantly affect the outcomes of peri-implant disease treatment, but there is currently a lack of uniform diagnosis and treatment standards.
BIOENGINEERING-BASEL
(2022)
Review
Dentistry, Oral Surgery & Medicine
Shu-Mi Chih, Chia -Dan Cheng, Siao-Han Chen, Cheng-En Sung, Ren-Yeong Huang, Wan-Chien Cheng
Summary: The aim of this systematic review was to assess the relationship between smoking and peri-implant microbiota. The findings suggest that smokers have significantly higher frequencies of anaerobic pathogens in healthy peri-implant tissues and a lower diversity of microbiota. Smoking may influence the composition of peri-implant microbiota.
JOURNAL OF DENTISTRY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Maria Clotilde Carra, Nicolas Blanc-Sylvestre, Alexandre Courtet, Philippe Bouchard
Summary: This systematic review and meta-analysis aimed to evaluate the effectiveness of risk factor control in preventing peri-implant diseases (PIDs) in adult dental implant patients. The study found that diabetic patients with good glycemic control have a lower risk of peri-implantitis and marginal bone loss. Regular attendance of supportive periodontal/peri-implant care also reduces the risk of PIDs. Augmentation of peri-implant keratinized mucosa is beneficial in controlling peri-implant inflammation and maintaining bone stability.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Medicine, General & Internal
Luminita Lazar, Timea Dako, Izabella-Eva Muresan, Mircea Suciu, George-Alexandru Maftei, Monica Tatarciuc, Ana-Petra Lazar
Summary: The aim of this study was to determine the advantages and limitations of laser therapy as an adjuvant in the treatment of peri-implant mucositis. The results showed that laser therapy significantly reduced bleeding on probing and led to a reduction in probing depth, but the difference was not statistically significant.
Article
Endocrinology & Metabolism
A. Scarano, F. Inchingolo, S. Scogna, L. Leo, A. Greco Lucchina, L. Mavriqi
Summary: Cement-retained restorations on implants offer better passive fit and aesthetics, but excess cement can lead to biological complications such as peri-implant tissue inflammation and periimplantitis. Careful cementation methods and materials can help prevent these cement-related peri-implant diseases.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Alejandra Chaparro, Pablo Atria, Ornella Realini, Lara J. Monteiro, Daniel Betancur, Stephanie Acuna-Gallardo, Valeria Ramirez, Maria Jose Bendek, Andres Pascual, Jose Nart, Victor Beltran, Antonio Sanz
Summary: The increased concentration of EVs with downregulated expression of miRNA-21-3p and miRNA-150-5p could be associated with the development of peri-implantitis.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Andrea Butera, Maurizio Pascadopoli, Matteo Pellegrini, Simone Gallo, Paolo Zampetti, Andrea Scribante
Summary: Peri-implant infections are common complications of dental implants, and this review evaluates the changes in oral microbiota associated with peri-implant disease. The study finds similarities and differences between peri-implantitis and periodontitis in microbial composition. The use of probiotics, in combination with mechanical debridement, shows potential for reducing peri-implant pockets. Transcriptomics can provide valuable insights into bacterial virulence factors for the prevention, diagnosis, and treatment of peri-implant pathology.
APPLIED SCIENCES-BASEL
(2022)
Review
Dentistry, Oral Surgery & Medicine
Masahiro Wada, Tomoaki Mameno, Motohiro Otsuki, Misako Kani, Yoshitaka Tsujioka, Kazunori Ikebe
Summary: Peri-implant diseases, including mucositis and peri-implantitis, have varying prevalence rates and risk indicators. Poor oral hygiene, lack of regular maintenance, diabetes, and history of periodontitis are strongly associated with the development of these diseases. However, there is no definitive conclusion about the correlations with other factors like smoking, implant superstructure shape, and keratinized mucosa condition. Further evidence-based studies are needed for predictable implant therapy in the long term.
JAPANESE DENTAL SCIENCE REVIEW
(2021)
Review
Infectious Diseases
Pier Carmine Passarelli, Andrea Netti, Michele Antonio Lopez, Eleonora Favetti Giaquinto, Giuseppe De Rosa, Gianmarco Aureli, Alina Bodnarenko, Piero Papi, Anna Starzynska, Giorgio Pompa, Antonio D'Addona
Summary: This study aimed to evaluate the effect of local/topical antibiotics for peri-implantitis treatment. While local antibiotic use can be considered a valid approach, contrasting results and high heterogeneity among studies suggest the need for future long-term clinical trials to achieve conclusive findings.
Review
Chemistry, Multidisciplinary
Yuchen Zhang, Emily Ming-Chieh Lu, David Moyes, Sadia Ambreen Niazi
Summary: This systematic review evaluates the impact of peri-implantitis on metabolic syndrome and provides management suggestions for patients with metabolic disorders. The findings suggest an association between peri-implantitis and altered metabolic factors, including lipid profile and HbA1c level. However, more high-quality studies are needed to confirm these results.
APPLIED SCIENCES-BASEL
(2023)
Review
Dentistry, Oral Surgery & Medicine
Thomas Spinell, Annika Kroger, Lena Freitag, Gregor Wurfl, Michael Lauseker, Reinhard Hickel, Moritz Kebschull
Summary: This study systematically reviewed in-vivo studies to examine the differences in gene expression patterns between peri-implant and periodontal tissues. The results suggest that these differences may be related to titanium particles from dental implants. However, limitations such as small sample sizes and insufficient re-analyzable data were identified in the eligible studies.
Article
Dentistry, Oral Surgery & Medicine
Giulia Brunello, Nicole Rauch, Kathrin Becker, Ahmad R. Hakimi, Frank Schwarz, Juergen Becker
Summary: This study aimed to evaluate the long-term clinical performance of two-piece zirconia implants in the posterior jaws over 9 years. The results showed a high survival rate for these implants, despite frequent mechanical and technical complications. Therefore, two-piece zirconia implants could be considered as a valid solution for replacing single teeth in the posterior jaws.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Annika Doeding, Mira Huefner, Franziska Nachtsheim, Viktoria Iffarth, Anna Boelter, Asisa Bastian, Judit Symmank, Nico Andreas, Patrick Schaedel, Maria Thuermer, Kathrin Becker, Michael Wolf, Collin Jacobs, Thomas Kamradt, Andreas Koeberle, Oliver Werz, Bernd Sigusch, Ulrike Schulze-Spaete
Summary: In this study, the effects of monounsaturated fatty acid (MUFA) oleic acid (OA) and saturated fatty acid (SFA) palmitic acid (PA) on gingival inflammation and periodontal disease pathology were investigated. The results suggest that the Mediterranean-style diet, which is rich in OA, may have preventive effects beyond its anti-inflammatory properties.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Editorial Material
Chemistry, Multidisciplinary
Kathrin Becker
APPLIED SCIENCES-BASEL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Frank Schwarz, Kathrin Becker, Christine Albrecht, Ausra Ramanauskaite, Amira Begic, Karina Obreja
Summary: This study compared the clinical effectiveness of different protocols for surgical therapy of peri-implantitis-related defects. All protocols showed improvements in clinical parameters.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Mira Huefner, Samuel David, Giulia Brunello, Robert Kerberger, Nicole Rauch, Caroline Viola Busch, Dieter Drescher, Christoph Bourauel, Kathrin Becker
Summary: This study evaluated the dimensional stability of five different resin/printer combinations (RPCs) after 3D printing and steam autoclaving. The results show that most of the surgical guides experienced minor but significant shrinkage due to both 3D printing and steam autoclaving, with variations observed between different RPCs.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Mihai Tarce, Kathrin Becker, Pierre Lahoud, Sohaib Shujaat, Reinhilde Jacobs, Marc Quirynen
Summary: The aim of this study was to introduce an objective method for evaluating the accuracy of implant position assessment in partially edentulous patients. Different techniques (conventional impression, intraoral scan, CBCT) were compared to an industrial scanner to obtain a reference 3D model. The results showed that all assessment techniques deviated from the reference industrial scan, with intraoral scans being slightly less accurate than both conventional impressions and CBCT.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Katharina Muecke, Caroline Busch, Juergen Becker, Dieter Drescher, Kathrin Becker
Summary: This study aimed to compare the effectiveness of online-only learning during the COVID-19 pandemic with pre-pandemic blended learning in three consecutive oral radiology courses. The results showed that students who received fewer video-based e-learning modules during the pandemic performed worse in final exams and knowledge gain.
EUROPEAN JOURNAL OF DENTAL EDUCATION
(2023)
Review
Dentistry, Oral Surgery & Medicine
Ausra Ramanauskaite, Kathrin Becker, Emilio A. A. Cafferata, Frank Schwarz
Summary: Guided bone regeneration (GBR) is a method used to treat bone defects at peri-implantitis sites, involving the placement of bone-filler particles and the use of a barrier membrane. The effectiveness of different GBR-supported treatments and their superiority compared to non-GBR treatments remains unclear. This analysis evaluates the long-term clinical efficacy of GBR-supported surgical therapy for peri-implantitis-related bone defects.
PERIODONTOLOGY 2000
(2023)
Article
Dentistry, Oral Surgery & Medicine
Sara Henricsson, Viveca Wallin Bengtsson, Stefan Renvert, Johan Sanmartin Berglund, Nina Lundegren, Pia Andersson
Summary: The study aimed to compare self-perceived oral health and orofacial appearance in three different cohorts of 60-year-old individuals. Data from the Swedish National Study of Aging and Care were analyzed, and a cross-sectional design was used. The results showed that the participants reported a low number of self-perceived problems with oral health. However, a higher proportion in the 2014-2015 cohort experienced problems with bleeding gums. Overall, the 60-year-olds irrespective of birth cohort perceived their oral health and orofacial appearance as satisfactory.
INTERNATIONAL JOURNAL OF DENTAL HYGIENE
(2023)
Article
Chemistry, Multidisciplinary
Marco Migliorati, Sara Drago, Alberto Lagazzo, Alessandra Campobasso, Giovanni Battista, Robert Kerberger, Dieter Drescher, Kathrin Becker
Summary: The present study investigated the effect of different curing times on the final thickness of direct 3D-printed orthodontic aligners. The results showed that curing time did not have an impact on the thickness, and there was no direct association between curing time or nitrogen generator usage and thickness. Additionally, a local thickness increase on the front teeth was observed under specific printing and centrifugation conditions.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Multidisciplinary
Annika Pliska, Lucia Schiavon, Giulia Brunello, Benedict Wilmes, Beryl Schwarz-Herzke, Dieter Drescher, Kathrin Becker
Summary: This study evaluated and compared the accuracy of two types of mini-implant insertion guides in a human cadaveric model. The results showed significant differences between planned and real positions, indicating the need for further research to improve accuracy in vivo.
APPLIED SCIENCES-BASEL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Frank Schwarz, Kathrin Becker, Fanya Lukman, Katharina Melissa Mueller, Victoria Sarabhai, Nicole Rauch, Robert Kerberger, Ausra Ramanauskaite, Robert Sader, Karina Obreja
Summary: This study investigated the extension of experimentally induced peri-implantitis lesions under various antiresorptive and antiangiogenic medications. Forty-eight albino rats were randomly assigned to different medication groups to establish peri-implantitis lesions over a period of 16 weeks. The results showed no significant effects of different medications on the extension of peri-implantitis lesions.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Katharina Muecke, Justine Igelbrink, Caroline Busch, Dieter Drescher, Juergen Becker, Kathrin Becker
Summary: The study compared students' performance in oral radiology courses before and after the pandemic, finding that post-pandemic students had lower baseline scores but significantly higher knowledge gains. The final exam scores in the first course also improved significantly.
JOURNAL OF DENTAL EDUCATION
(2023)
Review
Dentistry, Oral Surgery & Medicine
Luca Sbricoli, Lucia Schiavon, Giulia Brunello, Paola Brun, Kathrin Becker, Stefano Sivolella
Summary: This study evaluated the effectiveness of antiseptic mouthwashes in reducing the SARS-CoV-2 load clinically and in vitro. The results showed that mouthwashes were effective in decreasing the viral load in saliva. However, there were certain biases in the studies and a high degree of heterogeneity in the results. Therefore, large-scale trials are still needed to determine the best rinsing protocols.
JAPANESE DENTAL SCIENCE REVIEW
(2023)
Article
Endocrinology & Metabolism
Robert Kerberger, Giulia Brunello, Dieter Drescher, Bert van Rietbergen, Kathrin Becker
Summary: This study aimed to evaluate the impact of local stresses on implant migration and bone remodelling. The results showed that the magnitude of local stresses influenced bone remodelling and it can be speculated that stress-related bone resorption favored implant migration. After initial bone loss, net bone gain representing consolidation was observed.