Article
Infectious Diseases
Ivana Regecova, Jana Vyrostkova, Frantisek Zigo, Gabriela Gregova, Mariana Kovacova
Summary: This study aims to determine the prevalence of methicillin-resistant Staphylococcus chromogenes in samples of sheep's milk and cheeses, with findings showing high levels of antimicrobial resistance in the identified isolates, including resistance to commonly used antibiotics such as penicillin and tetracycline. The study also revealed a significant proportion of multidrug-resistant isolates, indicating a pressing issue of antibiotic resistance in nonaureus staphylococci.
Article
Veterinary Sciences
Maria Filippa Addis, Clara Locatelli, Martina Penati, Sara Fusar Poli, Valentina Monistero, Lucia Zingale, Nicola Rota, Claudia Gusmara, Renata Piccinini, Paolo Moroni, Valerio Bronzo
Summary: Non-aureus staphylococci and mammaliicocci (NASM) are associated with bovine mastitis and increased milk somatic cell count (SCC). Regional differences have been observed in their prevalence. This retrospective study provides new insights into the NASM species isolated from cow milk in Italy and their relationships with mammary gland health in modern dairy farms.
VETERINARY RESEARCH COMMUNICATIONS
(2023)
Article
Infectious Diseases
Yoshiro Hadano, Toshiyuki Hijikata, Ayako Miura, Shigeo Fujii, Yukikazu Awaya
Summary: This article reports three cases of S. pettenkoferi bacteremia and suggests that this organism may be a causative pathogen of catheter related blood stream infection and unknown source of bacteremia.
JOURNAL OF INFECTION AND CHEMOTHERAPY
(2022)
Article
Infectious Diseases
Uzoamaka A. Eke, Marilynn R. Fairfax, Robert Mitchell, Maureen Taylor, Hossein Salimnia
Summary: Staphylococcus pettenkoferi is a coagulase negative staphylococcus with unknown clinical relevance. This study found no data on S. pettenkoferi infection from the United States and suggests that more research is needed to determine its role as a pathogen in the country.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2021)
Article
Veterinary Sciences
Yu Jin Lee, Young Ju Lee
Summary: This study investigated the pathogenic potential of Coagulase-negative staphylococci (CoNS) isolated from bulk tank milk. The results showed that these bacteria exhibited a high prevalence of biofilm-forming ability and multidrug resistance. Therefore, developing a strong monitoring and sanitation program for dairy factories is crucial for ensuring hygienic milk production.
VETERINARY SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Fabio V. R. Portilho, Juliano Nobrega, Beatriz O. de Almeida, Andre R. Mota, Carolina L. de Paula, Fernando J. P. Listoni, Sandra M. G. Bosco, Alana L. Oliveira, Maria de Lourdes R. S. Cunha, Marcio G. Ribeiro
Summary: We investigated the oral microbiota of 100 healthy dogs and identified a complex community of bacteria and fungi, including potential pathogens to humans. We also observed multiple drug-resistant bacteria in the oral cavity of these dogs. This highlights the risk of transmission of microorganisms from dogs to humans and the challenges in treating infections caused by dog bites.
Article
Infectious Diseases
Kristine Batoon Ugaban, Rosemary C. She
Summary: Staphylococcus pettenkoferi is a coagulase-negative staphylococcal pathogen recently described. Most cases with this pathogen are considered clinically insignificant, but its significance remains uncertain in a few cases.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2022)
Article
Infectious Diseases
Katharina Last, Philipp M. Lepper, Philipp Jung, Hans-Joachim Schaefers, Sebastien Boutin, Klaus Heeg, Soren L. Becker, Dennis Nurjadi, Cihan Papan
Summary: Clinical and laboratory data on newly described staphylococcal species is rare. Our findings highlight the diagnostic pitfalls pertinent to novel and non-model organisms, in whom the correct identification is dependent on database accuracy.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2022)
Article
Environmental Sciences
Katarzyna Garbacz, Roman Kotlowski, Ewa Kwapisz
Summary: The study aimed to assess the sequencing of unique nucH gene fragment as a novel diagnostic method for difficult to identify staphylococcal human pathogenic strains. The results showed promising potential for identifying Staphylococcus species using nucH gene sequencing, with the need for a larger reference database to improve the method compared to standard 16S rDNA sequencing.
ENVIRONMENTAL MICROBIOLOGY REPORTS
(2021)
Article
Multidisciplinary Sciences
Pauline C. Goeller, Tabea Elsener, Dominic Lorge, Natasa Radulovic, Viona Bernardi, Annika Naumann, Nesrine Amri, Ekaterina Khatchatourova, Felipe Hernandes Coutinho, Martin J. Loessner, Elena Gomez-Sanz
Summary: The study reveals that staphylococcal phages have a predominant multi-species host range, facilitating horizontal gene transfer. Additionally, there is potential for antibiotic resistance gene transfer among phages sharing common hosts.
NATURE COMMUNICATIONS
(2021)
Article
Immunology
Denny Chin, Ronald S. Flannagan, Stephen W. Tuffs, Jeremy K. Chan, John K. McCormick, David E. Heinrichs
Summary: This study used random transposon insertion mutagenesis and RNA sequencing to discover that the agr quorum sensing system regulates the expression of virulence factors in S. lugdunensis. The agr-regulated effectors are important for the survival of S. lugdunensis in whole human blood and during encounters with macrophages. This research provides insight into the strategies used by this bacterium to cause disease.
INFECTION AND IMMUNITY
(2022)
Article
Infectious Diseases
Nathita Phumthanakorn, Nuvee Prapasarakul, Jitrapa Yindee, Dulyatad Gronsang
Summary: This study investigated the frequency, distribution, and antimicrobial resistance of CoNS from clinical samples from dogs and cats, revealing high levels of resistance and identification of methicillin-resistant CoNS. It points to the potential transfer of these bacteria to humans and highlights the diversity of SCCmec types and resistant strains, suggesting a reservoir of resistance genes among staphylococci.
MICROBIAL DRUG RESISTANCE
(2022)
Article
Biology
Aikaterini Nelli, Chrysoula (Chrysa) Voidarou, Brigkita Venardou, Konstantina Fotou, Anastasios Tsinas, Eleftherios Bonos, George C. Fthenakis, Ioannis Skoufos, Athina Tzora
Summary: Staphylococcus spp. in goat milk shows resistance to antibiotics, especially methicillin, which poses a concern for both animal and human health. Coagulase-negative staphylococci exhibit a broader range of antibiotic resistance compared to Staphylococcus aureus, with a higher percentage of resistant strains. The presence of drug-resistant strains and methicillin resistance in caprine Staphylococcus spp. is worrying for animal and public health.
Article
Microbiology
Sofie Marie Edslev, Caroline Meyer Olesen, Line Brok Norreslet, Anna Cacilia Ingham, Soren Iversen, Berit Lilje, Maja-Lisa Clausen, Jorgen Skov Jensen, Marc Stegger, Tove Agner, Paal Skytt Andersen
Summary: The presence of Staphylococcus aureus on the skin of atopic dermatitis patients is associated with disease severity, while the abundance of Staphylococcus hominis is negatively correlated with severity, suggesting their importance for skin health.
Article
Plant Sciences
Venkatesh Chunduri, Amandeep Kaur, Shubhpreet Kaur, Aman Kumar, Saloni Sharma, Natasha Sharma, Pargat Singh, Payal Kapoor, Satveer Kaur, Anita Kumari, Joy Roy, Jaspreet Kaur, Monika Garg
Summary: This study investigated the impact of day-night heat stress on wheat during the grain-filling stage through gene expression and proteomics approaches, revealing the involvement of multiple pathways and differential protein expression. Day heat stress caused early gene expression, while day-night heat stress suppressed gene expression by activating various pathways, ultimately leading to reduced yield and processing quality.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Veterinary Sciences
Elspeth Milne, Tim Nuttall, Katia Marioni-Henry, Chiara Piccinelli, Tobias Schwarz, Ali Azar, Jennifer Harris, Juliet Duncan, Michael Cheeseman
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2020)
Article
Dermatology
Deborah J. Gow, Hilary Jackson, Peter Forsythe, Tim Nuttall, Adam G. Gow, Richard J. Mellanby, David A. Hume
VETERINARY DERMATOLOGY
(2020)
Article
Veterinary Sciences
Ozana M. Hritcu, Vanessa M. Schmidt, Shebl E. Salem, Iuliana E. Maciuca, Ramona F. Moraru, Irina Lipovan, Mihai Mares, Gheorghe Solcan, Dorina Timofte
FRONTIERS IN VETERINARY SCIENCE
(2020)
Review
Dermatology
Ralf S. Mueller, Tim Nuttall, Christine Prost, Bianka Schulz, Petra Bizikova
Summary: The study reviewed evidence on the treatment of feline atopic syndrome and asthma, finding good efficacy of systemic glucocorticoids and ciclosporin, with limited evidence for other treatment options. More randomized controlled trials are needed to validate the efficacy of most treatment methods.
VETERINARY DERMATOLOGY
(2021)
Article
Dermatology
Richard Halliwell, Cherie M. Pucheu-Haston, Thierry Olivry, Christine Prost, Hilary Jackson, Frane Banovic, Tim Nuttall, Domenico Santoro, Petra Bizikova, Ralf S. Mueller
Summary: This study compared features of atopic diseases in humans and cats, suggesting similarities between feline allergic diseases and some human atopic diseases. The term Feline Atopic Syndrome and Feline Atopic Skin Syndrome were proposed to describe allergic conditions in cats, and a definition of Food Allergy was proposed for adverse food reactions in cats.
VETERINARY DERMATOLOGY
(2021)
Article
Veterinary Sciences
Cajsa M. Isgren, Nicola J. Williams, Owen D. Fletcher, Dorina Timofte, Richard J. Newton, Thomas W. Maddox, Peter D. Clegg, Gina L. Pinchbeck
Summary: The study described the antimicrobial resistance patterns of bacteria from clinical samples in the UK in 2018, revealing high rates of multidrug resistance in SSI/CRI/orthopaedic infections. Analysis of resistance in pathogens like E. coli and Staphylococcus species showed that some bacteria lacked readily available treatments for adult horses in the UK.
EQUINE VETERINARY JOURNAL
(2022)
Article
Multidisciplinary Sciences
Leonardos Mageiros, Guillaume Meric, Sion C. Bayliss, Johan Pensar, Ben Pascoe, Evangelos Mourkas, Jessica K. Calland, Koji Yahara, Susan Murray, Thomas S. Wilkinson, Lisa K. Williams, Matthew D. Hitchings, Jonathan Porter, Kirsty Kemmett, Edward J. Feil, Keith A. Jolley, Nicola J. Williams, Jukka Corander, Samuel K. Sheppard
Summary: This study identifies genetic elements associated with pathogenicity in avian E. coli using population genomics and pangenome-wide association studies, revealing the underlying mechanisms of pathogenicity in poultry.
NATURE COMMUNICATIONS
(2021)
Article
Dermatology
Lynette Cole, Tim Nuttall
Summary: Myringotomy is performed in cases of otitis media, abnormal tympanic membranes, etc.; it should be done under general anesthesia, preferably using a video otoscope; postoperative care includes keeping the tympanic membrane clean to prevent infection.
VETERINARY DERMATOLOGY
(2021)
Article
Microbiology
David A. Singleton, Pisut Pongchaikul, Shirley Smith, Rebecca J. Bengtsson, Kate Baker, Dorina Timofte, Stephen Steen, Matthew Jones, Larry Roberts, Fernando Sanchez-Vizcaino, Susan Dawson, P-J M. Noble, Alan D. Radford, Gina L. Pinchbeck, Nicola J. Williams
Summary: This study aimed to monitor antimicrobial resistance in companion animals in the UK, finding that the most commonly isolated bacteria in dogs and cats were Escherichia coli, with some bacteria showing resistance to multiple drugs. Genotypic characterization proved to be an efficient method for identifying important resistance trends in companion animals on a national scale.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Veterinary Sciences
E. F. Groat, N. J. Williams, G. Pinchbeck, B. Warner, A. Simpson, V. M. Schmidt
Summary: Dogs fed raw meat are more likely to carry antimicrobial-resistant Escherichia coli and Salmonella species compared to dogs fed non-raw diets. This poses a potential public health issue, especially for households with vulnerable members.
JOURNAL OF SMALL ANIMAL PRACTICE
(2022)
Article
Veterinary Sciences
Alexandra Royden, Robert Christley, Alison Prendiville, Nicola J. Williams
Summary: Campylobacter is a leading cause of human bacterial diarrhoeal disease globally, with poultry meat products contributing significantly to the cases. Farmers recognize the importance of biosecurity but have concerns about the current measures and heavy burden of responsibility placed on them.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Veterinary Sciences
Genever Morgan, Nicola Williams, Vanessa Schmidt, Daisy Cookson, Carrie Symington, Gina Pinchbeck
Summary: Food selection is an area of dog ownership where owners have direct control over their pet's wellbeing. This study aimed to provide further data regarding feeding practices and diet choice for UK dog owners with a focus on raw meat diets. The results showed that factors such as dog breed, neuter status, and age are associated with feeding raw meat diets. Owners who feed raw meat diets are more likely to prioritize a "more natural" diet and seek dietary advice from sources other than veterinary professionals. They perceive their diet choice to provide a wide range of health benefits, while non-raw meat diet feeders have different perceptions.
PREVENTIVE VETERINARY MEDICINE
(2022)
Article
Microbiology
Flavia Zendri, Cajsa M. Isgren, Jane Devaney, Vanessa Schmidt, Rachel Rankin, Dorina Timofte
Summary: The widespread occurrence of ESKAPE gram-negative organisms in veterinary ICU patients and hospital environments is described in this study. The most prevalent ESC-R GN isolates were found to be Enterobacter cloacae complex, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii complex, followed by Escherichia coli, and most of them carried a combination of genes encoding for beta-lactamases and ESBLs. Some genotypes showed likely intra-hospital transmission, suggesting possible transfer mediated via movement of staff and students. Importantly, isolates carrying transmissible resistance to last-resort antimicrobials were identified within the hospital environments, indicating the urgent need for infection control policies.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Genetics & Heredity
Natalie Ring, Alison S. Low, Bryan Wee, Gavin K. Paterson, Tim Nuttall, David Gally, Richard Mellanby, J. Ross Fitzgerald
Summary: Antimicrobial resistance is a major threat to human and animal health. This article presents a rapid diagnostic pipeline for identifying bacterial pathogens in clinical urine and skin samples of dogs using metagenomic nanopore sequencing. The pipeline can identify the pathogen within 5 hours and predict antibiotic sensitivity in urine samples.
MICROBIAL GENOMICS
(2023)