Article
Agriculture, Dairy & Animal Science
Martina Karasova, Csilla Tothova, Simona Grelova, Maria Fialkovicova
Summary: Babesia gibsoni is a parasite that causes red blood cell rupture in dogs, and its incidence has been increasing in European countries. Fighting dog breeds are more susceptible to the disease and may serve as potential sources of infection. The disease is often asymptomatic and easily introduced into Europe through importation or travel of dogs from endemic areas. This highlights the need for attention and study of B. gibsoni infection and its treatment, which can be challenging.
Article
Microbiology
Stephen J. Goodswen, Paul J. Kennedy, John T. Ellis
Summary: Infections from Babesia in red blood cells can lead to severe diseases in susceptible hosts. Bovine babesiosis and canine babesiosis are significant issues in the beef and dairy cattle industries, as well as with dogs. Machine learning methods have been developed to predict exportome members, providing valuable insights for laboratory validation.
Article
Biology
Mariana Ionita, Laurentiu Leica, Marion Wassermann, Emanuel Mitrea, Isabela Madalina Nicorescu, Ioan Liviu Mitrea
Summary: This study aimed to investigate the genetic diversity of Babesia spp. strains in a tick-endemic area in southeastern Romania. It identified the presence of both Babesia canis and Babesia vogeli strains, with different genotypes of B. canis. It also revealed the first evidence of genetic variability in canine babesiosis in Romania, providing a basis for further studies on the disease.
Article
Agriculture, Dairy & Animal Science
Olga Gojska-Zygner, Justyna Karabowicz, Justyna Bartosik, Wojciech Zygner
Summary: This study investigates the association between increased serum AST activity and renal indices in dogs with renal azotaemia infected with Babesia canis. The results suggest that increased serum AST activity may have a renal origin and the AST/ALT ratio could be a convenient renal index for recognizing renal azotaemia in canine babesiosis.
Article
Parasitology
Rafael Chiummo, Eva Zschiesche, Balazs Capari, Robert Farkas, Mathieu Chiquet, Dhimiter Rapti, Rezart Postoli, Alain Audry, Michael Leschnik
Summary: This study demonstrated that the use of fluralaner chewable tablets effectively prevents the transmission of Babesia canis in dogs under natural conditions, with a 100% efficacy rate.
PARASITES & VECTORS
(2023)
Review
Agriculture, Dairy & Animal Science
Wojciech Zygner, Olga Gojska-Zygner, Justyna Bartosik, Pawel Gorski, Justyna Karabowicz, Grzegorz Kotomski, Luke J. Norbury
Summary: Canine babesiosis is a disease caused by protozoan pathogens of the genus Babesia. The disease is caused by four species of large Babesia, with each species having specific regions of occurrence. B. vogeli is the most prevalent and widely distributed species globally, likely due to its wide range of vector species and mild infections, as well as its long evolutionary association with dogs. The main risk factors for large Babesia infection include living in rural areas, kennels or animal shelters, being in endemic regions, the season of the year (increased tick activity), tick infestation, and lack of acaricidal treatment.
Article
Veterinary Sciences
Susana Remesar, Jose Luis Arnal, Andrea Gomez, Alberto Prieto, David Garcia-Dios, Alfredo Benito, Rosario Panadero, Patrocinio Morrondo, Pablo Diaz
Summary: This case report highlights the existence of feline babesiosis caused by Babesia canis in Europe and its association with symptoms such as anemia and thrombocytopenia, providing molecular and epidemiological evidence.
BMC VETERINARY RESEARCH
(2022)
Article
Veterinary Sciences
S. Remesar, A. Mendez, A. Benito, A. Prieto, D. Garcia-Dios, C. M. Lopez, R. Panadero, P. Diez-Banos, P. Morrondo, P. Diaz
Summary: In Europe, most cases of canine babesiosis are caused by Babesia canis, Babesia vogeli, and Babesia vulpes. A rapid and efficient multiplex PCR was developed to simultaneously detect and distinguish between large and small forms of the parasite. The multiplex PCR successfully discriminated between the two Babesia groups and can be used as a reliable tool for detecting infections in dogs. It allows for rapid administration of an appropriate treatment, improving the survival rate of infected animals and aiding in understanding the prevalence and distribution of B. vulpes.
RESEARCH IN VETERINARY SCIENCE
(2023)
Review
Microbiology
Wojciech Zygner, Olga Gojska-Zygner, Luke J. J. Norbury
Summary: Canine babesiosis is a tick-borne parasitic disease that leads to anemia in infected dogs. The anemia is not caused directly by the pathogen, but rather by the immune response to the infection. Pro-inflammatory cytokines and chemokines play a role in the mechanisms leading to anemia in canine babesiosis, including antibody production, erythrophagocytosis, oxidative damage, and splenic sequestration of red blood cells.
Article
Microbiology
Olga Pawelczyk, Damian Kotela, Marek Asman, Joanna Witecka, Peter Wilhelmsson, Paulina Bubel, Krzysztof Solarz
Summary: Tick-borne microorganisms, including Babesia canis, are important agents causing infectious diseases in humans and animals. This study reports two cases of symptomatic canine babesiosis caused by Babesia canis in domestic dogs from Poland, as well as the presence of Dermacentor reticulatus ticks on one of the infected dogs. Molecular analysis confirmed the presence of Babesia canis in the dogs' blood, with the obtained sequence being identical to a known isolate.
Article
Microbiology
Jana Radzijevskaja, Dalyte Mardosaite-Busaitiene, Asta Aleksandravieiene, Birute Karveliene, Migle Razgunaite, Inga Stadaliene, Algimantas Paulauskas
Summary: Canine babesiosis is a rapidly expanding tick-borne disease in central and northeast Europe, and different genotypes of B. canis have been identified in Lithuania.
Article
Public, Environmental & Occupational Health
Solomon Ngutor Karshima, Magdalene Nguvan Karshima, Musa Isiyaku Ahmed
Summary: Human babesiosis, caused by Babesia parasites and transmitted by ticks, is a tick-borne disease with varying infection rates globally. Europe has the highest infection rate at 4.17%, while North America has a rate of 1.54%. Factors influencing infection rates include species of Babesia, income levels, and population demographics. Controlling tick populations in human settlements and screening blood transfusions are recommended to address this emerging public health threat.
PATHOGENS AND GLOBAL HEALTH
(2022)
Article
Parasitology
Dorota Dwuznik-Szarek, Ewa J. Mierzejewska, Anna Rodo, Katarzyna Gozdzik, Jolanta Behnke-Borowczyk, Dorota Kiewra, Natalia Kartawik, Anna Bajer
Summary: The study demonstrates the continuous expansion of two populations of D. reticulatus ticks in Poland, mainly along river basins. There is a marked colonization of the gap zone and a decreasing distance between Western and Eastern tick populations. The incidence of canine babesiosis is lower in Western Poland and the gap area, while higher in Central and Eastern Poland, suggesting strong associations between tick distribution and occurrence of babesiosis.
PARASITES & VECTORS
(2021)
Article
Parasitology
Yanbo Wang, Shangdi Zhang, Xiaoyun Li, Yueli Nian, Xinyue Liu, Junlong Liu, Hong Yin, Guiquan Guan, Jinming Wang
Summary: A real-time PCR-high-resolution melting method was developed to accurately identify the six Babesia strains causing human babesiosis. The method showed high sensitivity and specificity, making it suitable for epidemiological investigations and pre-transfusion screening.
PARASITES & VECTORS
(2023)
Article
Immunology
Reginaldo G. Bastos, Jacob M. Laughery, Sezayi Ozubek, Heba F. Alzan, Naomi S. Taus, Massaro W. Ueti, Carlos E. Suarez
Summary: This study investigated immune correlates of protection against acute bovine babesiosis by infecting cows with attenuated and virulent strains of Babesia bovis. The results demonstrated changes in the profile of blood immune cells and cytokine expression that are associated with protection against acute bovine babesiosis.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Microbiology
Pascal Arne, Veronica Risco-Castillo, Gregory Jouvion, Cecile Le Barzic, Jacques Guillot
Summary: Fungi of the genus Aspergillus can thrive in various environments and pose a serious threat to birds. The importance of innate immunity and exposure level varies in the development of Aspergillosis among avian species and epidemiological situations. Due to the low efficacy of treatments, understanding the conditions favoring the emergence of Aspergillosis is crucial for prevention.
Article
Infectious Diseases
Sarah Bonnet, Thierry Blisnick, Charbel Al Khoury, Jacques Guillot
Summary: This study identified fungal contamination in a laboratory-reared colony of Ixodes ricinus, with three different species of fungi isolated from the ticks. While there is no direct evidence of lethal infections in ticks, the heavy fungal growth and high mortality rates suggest the potential of these fungi as entomopathogenic agents for tick control.
TICKS AND TICK-BORNE DISEASES
(2021)
Article
Biotechnology & Applied Microbiology
M. Voinot, F. Arroyo, J. A. Hernandez, A. Paz-Silva, R. Sanchez-Andrade, R. Bermudez, J. Guillot, L. M. Madeira de Carvalho, M. S. Arias, C. F. Cazapal-Monteiro
Summary: The study tested the innocuousness of prolonged ingestion of commercial nutritional pellets containing spores of Mucor circinelloides and Duddingtonia flagrans on grazing dairy heifers. The results showed that daily ingestion of these pellets over a long period of time is completely safe for the heifers, with no negative impacts observed.
BIOCONTROL SCIENCE AND TECHNOLOGY
(2022)
Article
Dermatology
Forough Shamsizadeh, Ali Zarei Mahmoudabadi, Maryam Shariat Nabavi, Jacques Guillot, Simin Taghipour, Ali Rezaei-Matehkolaei
Summary: This study evaluated the in vitro antifungal activity of common and new antifungals against a set of environmental and clinical geophilic dermatophyte isolates, finding that luliconazole, terbinafine, and efinaconazole exhibited the highest efficacy. Further surveillance studies are recommended to confirm the implications of such in vitro data for the clinical recovery rate of dermatophytosis with geophilic species following antifungal therapy.
Review
Microbiology
Barbara Moroni, Luca Rossi, Charlotte Bernigaud, Jacques Guillot
Summary: Zoonotic scabies, also known as pseudoscabies, is a self-limiting disease. Although it is commonly believed that scabies mites from animals cannot reproduce and persist on human skin, several case reports have mentioned the persistence of symptoms and occasionally mites. This review aims to collect and organize literature on zoonotic transmission of Sarcoptes scabiei, focusing on the source of outbreak, transmission circumstances, diagnosis, and treatment.
Article
Microbiology
Clemence Nadal, Maud Marsot, Gael Le Metayer, Pascal Boireau, Jacques Guillot, Sarah I. Bonnet
Summary: This study aimed to investigate the spatio-temporal variations of equine piroplasmosis in France and provide baseline information regarding the sero-epidemiology of Babesia caballi and Theileria equi infection in horses. The results showed that horses from southern regions of France were the most affected by B. caballi and T. equi infection, while the proportion of horses having antibodies against T. equi increased over time.
Article
Microbiology
Arnaud Jabet, Anne-Cecile Normand, Alicia Moreno-Sabater, Jacques Guillot, Veronica Risco-Castillo, Sophie Brun, Magalie Demar, Romain Blaizot, Cecile Nabet, Ann Packeu, Renaud Piarroux
Summary: The objective of the study was to reduce recurrent errors between phylogenetically close species by adding new reference spectra. Diversifying the references and adding spectra from various culture media and culture durations improved identification performance, although confusion remained between certain closely related species.
Article
Computer Science, Interdisciplinary Applications
Sk Imran Hossain, Jocelyn de Goer de Herve, Md Shahriar Hassan, Delphine Martineau, Evelina Petrosyan, Violaine Corbin, Jean Beytout, Isabelle Lebert, Jonas Durand, Irene Carravieri, Annick Brun-Jacob, Pascale Frey-Klett, Elisabeth Baux, Celine Cazorla, Carole Eldin, Yves Hansmann, Solene Patrat-Delon, Thierry Prazuck, Alice Raffetin, Pierre Tattevin, Gwenael Vourc'h, Olivier Lesens, Engelbert Mephu Nguifo
Summary: A lightweight CNN application can assist users with early diagnosis of Lyme disease on mobile devices, while resource-intensive CNN applications can aid non-expert practitioners with accurate diagnosis. This study extensively analyzes the effectiveness of CNNs for diagnosing Lyme disease and provides guidelines for model selection considering resource constraints.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Health Care Sciences & Services
Isabelle Lebert, Severine Bord, Christine Saint-Andrieux, Eva Cassar, Patrick Gasqui, Frederic Beugnet, Karine Chalvet-Monfray, Sophie O. Vanwambeke, Gwenael Vourc'h, Magalie Rene-Martellet
Summary: Using a knowledge-based method, this study mapped the habitat suitability for I. ricinus ticks in France and Corsica, taking into account climate, land cover, altitude, and density of wild ungulates. The results showed that most areas of France and Corsica are suitable for I. ricinus, with particularly suitable habitats in central, north-eastern and south-western France. The study also demonstrated the value of multi-criteria decision analysis in estimating tick abundance and highlighting priority areas for preventive measures.
Article
Multidisciplinary Sciences
Valerie Andriantsoanirina, Jacques Guillot, Michel Ratsimbason, Ghozlene Mekhloufi, Faliarivony Randriamialinoro, Lalasoanirina Ranarivelo, Frederic Ariey, Remy Durand
Summary: This study evaluated the acaricidal activity of numerous plant essential oils against Sarcoptes scabiei, the mite responsible for scabies. Cinnamomum zeylanicum and Ocimum sanctum oils demonstrated the highest activity and may have potential as topical treatments.
SCIENTIFIC REPORTS
(2022)
Article
Infectious Diseases
Estelle Cateau, Antoine Leclerc, Noemie Cartier, Isabel Valsecchi, Eric Bailly, Ronan Le Senechal, Margaux Becerra, Brice Le Gallou, Rose-Anne Lavergne, Adelaide Chesnay, Jean-Patrice Robin, Carolyn Cray, Nicolas Goddard, Milan Thorel, Jacques Guillot, Baptiste Mulot, Guillaume Desoubeaux
Summary: The incidence of aspergillosis in the penguin population of a French zoo was found elevated, mostly in juveniles. The fungal contamination was high in the surrounding environment, especially at the end of summer. Globally, a great level of genetic diversity was observed, except for one clonal strain.
Article
Mycology
A. Cmokova, M. Kolarik, J. Guillot, V Risco-Castillo, F. J. Cabanes, P. Nenoff, S. Uhrlass, R. Dobias, N. Mallatova, T. Yaguchi, R. Kano, I Kuklova, P. Lyskova, K. Mencl, P. Hamal, A. Peano, V Hubka
Summary: Trichophyton erinacei is the main causative agent of hedgehog dermatophytosis and its population genetics and classification are of great clinical significance. The study identified two subpopulations within T. erinacei, each associated with different hosts, but with gene flow between them. The study provides a suitable method for further exploration of the epidemiology of this pathogen and highlights the importance of using multigene phylogeny and other independent molecular markers.
Article
Immunology
Sana Jemel, Yannick Raveloarisaona, Anne-Laure Bidaud, Elie Djenontin, Aicha Kallel, Jacques Guillot, Kalthoum Kallel, Francoise Botterel, Eric Dannaoui
Summary: Azole resistance in Aspergillus fumigatus is a major concern for the optimal management of patients with invasive aspergillosis. This study evaluates the combination of caspofungin with voriconazole or posaconazole for the treatment of azole-resistant strains. In vitro and in vivo experiments were conducted, and the combination therapy showed promising results.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Parasitology
Barbara Moroni, Francesco Albanese, Anna Rita Molinar Min, Mario Pasquetti, Jacques Guillot, Simone Roberto Rolando Pisano, Marie-Pierre Ryser-Degiorgis, Silvia Ruefenacht, Dominique Gauthier, David Cano-Terriza, Dino Scaravelli, Luca Rossi, Andrea Peano
Summary: This study aimed to characterize the genetic structure of Sarcoptes scabiei mites from domestic cats and Eurasian lynx, comparing them with mites from sympatric domestic and wild carnivores. The results showed that the genetic structure of the mites exhibited a geographical distribution pattern, which may be due to interactions between different hosts living in the same ecological niche rather than simple infection among hosts belonging to the same taxon.
Article
Parasitology
Irene Vonfeld, Thibaut Prenant, Bruno Polack, Jacques Guillot, Benoit Quintard
Summary: This study investigated the prevalence of gastrointestinal parasites in non-human primates housed in zoological institutions in France and developed a decision-making tree and diagnostic atlas for parasite diagnosis.
