Article
Multidisciplinary Sciences
Alleluia Lima Losno Ledesma, Daniele Leite Rodrigues, Isabella Monteiro de Castro Silva, Carlos Augusto Oliveira, Fayez Bahmad
Summary: The study found that 300 mg of caffeine did not significantly alter the psychoacoustic measures, electroacoustic measures or the degree of discomfort related to tinnitus in patients.
Article
Chemistry, Medicinal
Reyhaneh Gudarzi, Fatemeh Shabani, Sakineh Mohammad-Alizadeh-Charandabi, Elham Naghshineh, Elnaz Shaseb, Mojgan Mirghafourvand
Summary: This study aimed to determine the effect of curcumin on painful symptoms and quality of life in women with endometriosis. The results showed that curcumin did not have a significant impact on pain symptoms or quality of life. Future clinical trials are needed to further investigate the role of curcumin in endometriosis.
PHYTOTHERAPY RESEARCH
(2023)
Article
Chemistry, Medicinal
Ali Khamevar, Mohammad Ali Ebrahimzadeh, Mahmood Moosazadeh, Masoud Shayesteh Azar, Majid Saeedi, Adel Bakhtiary Far, Seyde Sedighe Yousefi
Summary: A clinical trial involving 60 elderly patients showed that Pistacia atlantica gum ointment significantly improved symptoms of knee osteoarthritis, including reducing joint stiffness, pain, and improving function compared to a placebo.
PHYTOTHERAPY RESEARCH
(2021)
Article
Surgery
Niclas Dohrn, Helin Yikilmaz, Magnus Laursen, Faisal Khesrawi, Frederik Bjerg Clausen, Frederik Sorensen, Henrik Loft Jakobsen, Steffen Brisling, Jakob Lykke, Jens Ravn Eriksen, Mads Falk Klein, Ismail Gogenur
Summary: The study did not find significant differences in postoperative recovery between minimally invasive right colectomy with intra-corporeal anastomosis compared to extra-corporeal anastomosis.
Article
Dentistry, Oral Surgery & Medicine
Fernando Valentim Bitencourt, Silvia Cardoso De David, Jasper da Silva Schutz, Alfredo Otto Kirst Neto, Fernanda Visioli, Tiago Fiorini
Summary: This study suggests that photobiomodulation therapy can accelerate postoperative pain resolution and wound healing, reduce medication consumption, and significantly improve patient satisfaction.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Article
Medicine, General & Internal
Joel Pollet, Riccardo Buraschi, Giorgia Ranica, Simone Pancera, Denise Anastasi, Rossella Fazio, Serena Monteleone, Eleonora Lena, Valeria Floridi, Franco Zucchini, Maurizio Vincenzo Falso
Summary: The study assessed the effect of a newly designed custom-made insole called PRO-STEP on subjects with Parkinson's Disease. The results showed that PRO-STEP did not significantly improve the walking time and gait parameters in PD patients. However, PD patients were satisfied with the PRO-STEP insoles. Future studies should consider modifying the stimulation method to improve its effectiveness in PD patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Andreas Hagen Rossevold, Nikolai Kragoe Andresen, Christina Annette Bjerre, Bjornar Gilje, Erik Hugger Jakobsen, Sunil Xavier Raj, Ragnhild Sorum Falk, Hege Giercksky Russnes, Thea Jahr, Randi Ruud Mathiesen, Jon Lomo, Oystein Garred, Sudhir Kumar Chauhan, Ragnhild Reehorst Lereim, Claire Dunn, Bjorn Naume, Jon Amund Kyte
Summary: This study evaluated the efficacy and safety of adding atezolizumab to immune-stimulating chemotherapy in patients with metastatic triple-negative breast cancer. The results showed that the combination treatment improved progression-free survival but also increased the occurrence of adverse events.
Article
Medicine, General & Internal
Karina Cardenas-Jaen, Alicia Vaillo-Rocamora, Angel Gracia, Pramoud K. Garg, Pedro Zapater, Georgios I. Papachristou, Vikesh K. Singh, Bechien U. Wu, Enrique de-Madaria
Summary: The SIMBA trial aims to determine whether simvastatin, a safe, widely used, and inexpensive drug, can alter the natural course of recurrent pancreatitis.
FRONTIERS IN MEDICINE
(2021)
Article
Chemistry, Medicinal
Maryam Shayani Rad, Mohsen Moohebati, Seyed Ahmad Mohajeri
Summary: In this study, the antihypertensive effects of celery seed extract were investigated in a clinical trial. The results showed that the extract significantly reduced systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, and pulse pressure without any significant side effects.
PHYTOTHERAPY RESEARCH
(2022)
Article
Chemistry, Medicinal
Zohreh Ghaem Far, Siavash Babajafari, Javad Kojuri, Salman Mohammadi, Mehran Nouri, Pouya Rostamizadeh, Mohammad Hossein Rahmani, Mohsen Azadian, Elham Ashrafi-Dehkordi, Alireza Zareifard, Reza Golchin Vafa, Seyed Mohammad Mazloomi
Summary: The study found that spirulina-fortified dressing significantly reduced blood pressure and certain lipid levels in patients with hypertension, showing potential in alleviating chronic diseases.
PHYTOTHERAPY RESEARCH
(2021)
Article
Oncology
Reza Ershadi, Matin Vahedi, Hossein Kazemi Zadeh, Farhad Fathi, Hossein Ebrahimpour, Javad Sarbaz Zadeh, Shahab Rafieian
Summary: In this randomized controlled trial, we found that adjunctive treatment with subcutaneous octreotide can improve the efficacy of pleurodesis with talc powder, reducing pleural effusion production and hospital stay while decreasing treatment failure. However, it does not lower the risk of relapse and does not have significant side effects.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Dentistry, Oral Surgery & Medicine
Michael Willian Favoreto, Laina Vochikovski, Renata Maria Oleniki Terra, Veridiana Silva Campos, Mariana Evangelista Santos, Sonia Saeger Meireles, Alessandra Reis, Alessandro D. Loguercio
Summary: The study evaluated the use of Otosporin (R) topical application before in-office bleaching with a 35% hydrogen peroxide gel to reduce tooth sensitivity and enhance bleaching effectiveness. Results showed no significant difference in risk and intensity of tooth sensitivity between groups, indicating that Otosporin (R) did not have a significant impact on reducing sensitivity or affecting bleaching effectiveness.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Gregory M. Marcus, Jonathan W. Dukes, Eric Vittinghoff, Gregory Nah, Nitish Badhwar, Joshua D. Moss, Randall J. Lee, Byron K. Lee, Zian H. Tseng, Tomos E. Walters, Vasanth Vedantham, Rachel Gladstone, Shannon Fan, Emily Lee, Christina Fang, Kelsey Ogomori, Trisha Hue, Jeffrey E. Olgin, Melvin M. Scheinman, Henry Hsia, Vijay A. Ramchandani, Edward P. Gerstenfeld
Summary: This study demonstrates that acute exposure to alcohol reduces atrial effective refractory periods, particularly in the pulmonary veins, suggesting a direct mechanistic link between alcohol and immediate proarrhythmic effects in human atria.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Neurosciences
Luciana L. Louzada, Flavio V. Machado, Juliana L. Quintas, Guilherme A. Ribeiro, Monica V. Silva, Dayde L. Mendonca-Silva, Bruno S. B. Goncalves, Otavio T. Nobrega, Einstein F. Camargos
Summary: Short-term use of zolpidem or zopiclone in older patients with Alzheimer's dementia and insomnia appears to be clinically beneficial, although safety and tolerance issues need personalized management in healthcare settings and further exploration in subsequent trials.
NEUROPSYCHOPHARMACOLOGY
(2022)
Article
Gastroenterology & Hepatology
Jee-Fu Huang, Chia-Yen Dai, Chung-Feng Huang, Pei-Chien Tsai, Ming-Lun Yeh, Po-Yau Hsu, Shiu-Feng Huang, Ming-Jong Bair, Nai-Jen Hou, Ching- Huang, Po-Cheng Liang, Yi-Hung Lin, Chih-Wen Wang, Ming-Yen Hsieh, Shinn-Chern Chen, Zu-Yau Lin, Ming-Lung Yu, Wan-Long Chuang
Summary: The study demonstrated that pioglitazone was effective and safe in treating Asian NASH patients, leading to significant reductions in inflammation, improvement in liver fat, and no significant adverse events.
HEPATOLOGY INTERNATIONAL
(2021)
Article
Behavioral Sciences
James Andrew Oxley, Rob Christley, Carri Westgarth
JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH
(2019)
Article
Veterinary Sciences
Z. G. Terfa, S. Garikipati, G. Kassie, J. M. Bettridge, R. M. Christley
PREVENTIVE VETERINARY MEDICINE
(2018)
Article
Veterinary Sciences
S. Sudunagunta, D. Green, R. Christley, J. Dukes-McEwan
JOURNAL OF VETERINARY CARDIOLOGY
(2019)
Article
Veterinary Sciences
Tamzin Furtado, Elizabeth Perkins, Gina Pinchbeck, Catherine McGowan, Francine Watkins, Robert Christley
Summary: This study provides insight into leisure horse owners' perceptions of weight and weight management, offering valuable information for communicating with owners about weight, tailoring weight management strategies, and promoting positive welfare.
EQUINE VETERINARY JOURNAL
(2021)
Article
Agriculture, Dairy & Animal Science
Katrina E. Holland, Sara C. Owczarczak-Garstecka, Katharine L. Anderson, Rachel A. Casey, Robert M. Christley, Lauren Harris, Kirsten M. McMillan, Rebecca Mead, Jane K. Murray, Lauren Samet, Melissa M. Upjohn
Summary: On 23 March 2020, the UK Government imposed a nationwide lockdown as part of efforts to reduce the impact of COVID-19. This study aimed to explore how dog ownership in the UK was affected during this period. Data from open-ended survey questions and electronic diaries revealed three main themes: spending more time at home with dogs, changes in walking practices, and changes in behavior and training. Owners appreciated the extra time with their dogs but were concerned about the potential negative effects on their dogs when left alone. Despite the increased time together, few owners provided alone time for their dogs during the lockdown. Owners also found value in walking their dogs as part of daily exercise but felt restrictions limited sufficient exercise and interaction opportunities with other dogs. New undesirable behaviors in dogs, such as barking or clinginess, were observed during this period. Recommendations include helping dog owners teach their dogs to cope with being alone.
Article
Agriculture, Dairy & Animal Science
Katrina E. Holland, Rebecca Mead, Rachel A. Casey, Melissa M. Upjohn, Robert M. Christley
Summary: Studies have shown that many dog owners did not plan to acquire a dog, with some taking in dogs due to relatives or friends unable to care for them, and others spontaneously encountering dogs in need. Emotional attachments and a desire to help vulnerable animals were common motivations for keeping the dog. Further research is needed to understand the prevalence of unplanned dog acquisitions.
Editorial Material
Veterinary Sciences
Tamzin Furtado, Robert Christley
EQUINE VETERINARY JOURNAL
(2021)
Article
Environmental Sciences
Sara C. Owczarczak-Garstecka, Robert M. Christley, Francine Watkins, Huadong Yang, Carri Westgarth
Summary: This study examines how workers in workplaces such as delivery, veterinary and dog rescue sectors negotiate the risk of dog bites, and how procedures in place may not always align with the actual risks faced by the workers. The findings suggest that employees often rely on experiential knowledge and subjective judgment when dealing with dog bite risks, which can lead to disregarding procedures and potential blame on victims.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Agriculture, Dairy & Animal Science
Naomi D. Harvey, Robert M. Christley, Kassandra Giragosian, Rebecca Mead, Jane K. Murray, Lauren Samet, Melissa M. Upjohn, Rachel A. Casey
Summary: This study surveyed dog owners in the UK to examine the changes in separation-related behaviors (SRBs) during the COVID-19 pandemic and post-lockdown period. The results showed that there were significant changes in dogs' SRBs, with dogs that had the most reduction in alone time during lockdown being at the highest risk of developing new SRBs after the restrictions eased.
Article
Infectious Diseases
Hannah E. Brindle, Leonardo S. Bastos, Robert Christley, Lucie Contamin, Le Hai Dang, Dang Duc Anh, Neil French, Michael Griffiths, Behzad Nadjm, H. Rogier van Doorn, Pham Quang Thai, Tran Nhu Duong, Marc Choisy
Summary: The incidence of AES in Vietnam varies by region and season, with the highest incidence during the summer in the northern provinces. The cause of AES remains unknown in many cases. This study aims to understand the spatio-temporal distribution of, and risk factors for AES in Vietnam to help hypothesise the aetiology.
BMC INFECTIOUS DISEASES
(2023)
Article
Multidisciplinary Sciences
Eleanor Robertson, Cherinet Abera, Kelly Wood, Kabeba Deressa, Samuel Mesfin, Claire Scantlebury
Summary: Antifungal medications are scarce in Ethiopia, leading to limited access to treatment for fungal diseases, particularly histoplasmosis, which affects both humans and equids. This study explores the factors that affect access to antifungals and identifies key limitations, including structural issues in the pharmaceutical supply chain and human factors such as perception of expense and availability of alternative treatments. The findings highlight the urgent need for improved access to antifungal medications in Ethiopia and the importance of addressing these factors to enhance disease control.
Article
Agriculture, Dairy & Animal Science
Katharine L. Anderson, Rachel A. Casey, Ben Cooper, Melissa M. Upjohn, Robert M. Christley
Summary: This paper provides an overview of a National Dog Survey in the UK, aiming to understand the current dog population and their owners. The results highlight trends and patterns, including the impact of the COVID-19 pandemic. Understanding dog demographics is important for addressing their welfare needs and developing appropriate interventions.
Article
Agriculture, Dairy & Animal Science
Elly Hiby, Tuntikorn Rungpatana, Alicja Izydorczyk, Craig Rooney, Mike Harfoot, Robert Christley
Summary: In Greater Bangkok, free-roaming dogs are tolerated by some citizens, but also raise concerns about dog welfare, nuisance behaviors and the risk of rabies transmission. A 5-year Catch, Neuter, Vaccinate and Return (CNVR) intervention was conducted to control the population of these dogs and prevent rabies. The evaluation of this intervention found a reduction in dog density, dog rabies cases, and improvement in dog-human relationships. However, the presence of other sources of free-roaming dogs, mainly abandoned or lost owned dogs, means that additional interventions targeting these dogs are necessary for effective dog population management.
Article
Agriculture, Dairy & Animal Science
Rebecca Mead, Katrina E. Holland, Rachel A. Casey, Melissa M. Upjohn, Robert M. Christley
Summary: This study investigates dog acquisition in the UK and finds that nearly half of existing dog owners do not research or seek advice before acquiring a dog. Individuals with previous dog ownership experience are less likely to undertake pre-acquisition research, while younger prospective owners and those with formal education qualifications are more likely to do so. Findings have implications for organizations providing advice on dog acquisition and ownership, emphasizing the need for increased awareness and targeted interventions to encourage pre-acquisition research.
Article
Health Care Sciences & Services
Kirsty Marie McIntyre, Frederick J. Bolton, Rob M. Christley, Paul Cleary, Elizabeth Deja, Ann E. Durie, Peter J. Diggle, Dyfrig A. Hughes, Simon de Lusignan, Lois Orton, Alan D. Radford, Alex J. Elliot, Gillian E. Smith, Darlene A. Snape, Debbi Stanistreet, Roberto Vivancos, Craig Winstanley, Sarah J. O'Brien
JMIR RESEARCH PROTOCOLS
(2019)