Predicting and characterizing selective multiple drug treatments for metabolic diseases and cancer

Predicting selective drug targets in cancer through metabolic networks

(2011) O. Folger et al.   Molecular Systems Biology

Epistatic Interaction Maps Relative to Multiple Metabolic Phenotypes

(2011) Evan S. Snitkin et al.   PLoS Genetics

Deep epistasis in human metabolism

(2010) Marcin Imielinski et al.   CHAOS

Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

(2010) Katherine L. B. Borden et al.   LEUKEMIA & LYMPHOMA

Rasagiline: A novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity

(2010) Orly Weinreb et al.   PROGRESS IN NEUROBIOLOGY

Optimal drug combinations and minimal hitting sets

(2009) Alexei Vazquez   BMC Systems Biology

Flux balance analysis of biological systems: applications and challenges

(2009) K. Raman et al.   BRIEFINGS IN BIOINFORMATICS

Dihydroorotate dehydrogenase inhibitor A771726 (leflunomide) induces apoptosis and diminishes proliferation of multiple myeloma cells

(2009) P. Baumann et al.   MOLECULAR CANCER THERAPEUTICS

Effects of simvastatin, acetylsalicylic acid, and rosiglitazone on proliferation of normal and cancerous prostate epithelial Cells at therapeutic concentrations

(2009) Teemu J. Murtola et al.   PROSTATE

Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice

(2008) Soo-Jeong Cho et al.   INTERNATIONAL JOURNAL OF CANCER

Metabolic Network Model of a Human Oral Pathogen

(2008) V. Mazumdar et al.   JOURNAL OF BACTERIOLOGY

High-order combination effects and biological robustness

(2008) Joseph Lehár et al.   Molecular Systems Biology