Article
Neurosciences
Jing Qi, Bo-Zhi Li, Ying Zhang, Bei Pan, Yu-Hong Gao, Hao Zhan, Yong Liu, Yong-Cong Shao, Xie-Chuan Weng, Xi Zhang
Summary: The study found that sleep deprivation leads to changes in the topological properties of brain functional networks at both global and nodal levels, especially in regions such as frontoparietal networks, sensorimotor networks, temporal regions, and salience networks. Alterations in the posterior superior temporal sulcus and insula were associated with changes in vigilant attention performance after sleep deprivation.
Article
Chemistry, Analytical
Fabrizio Vecchio, Chiara Pappalettera, Francesca Miraglia, Francesca Alu, Alessandro Orticoni, Elda Judica, Maria Cotelli, Francesca Pistoia, Paolo Maria Rossini
Summary: Parkinson's disease can globally modulate the cortical connectivity of the brain, altering functional network organization and resulting in motor and non-motor symptoms. This approach based on a low-cost and non-invasive technique may be useful for early diagnosis, monitoring disease progression, and evaluating treatments.
Article
Computer Science, Information Systems
Chisho Takeoka, Toshimasa Yamazaki, Yoshiyuki Kuroiwa, Kimihiro Fujino, Toshiaki Hirai, Hidehiro Mizusawa
Summary: Prion disease was characterized by comparing brain functional connectivity network (BFCN) constructed from 16-ch scalp-recorded electroencephalograms (EEGs). The connectivity between each pair of nodes (electrodes) was computed using synchronization likelihood (SL). BFCN was applied to graph theory to differentiate prion disease patients from healthy elderlies and dementia groups.
IEICE TRANSACTIONS ON INFORMATION AND SYSTEMS
(2023)
Article
Neurosciences
Ryan J. Hubbard, Iman Zadeh, Aaron P. Jones, Bradley Robert, Natalie B. Bryant, Vincent P. Clark, Praveen K. Pilly
Summary: Memory consolidation during REM sleep and enhancing metamemory through brain stimulation have been well-studied. A recent study found that changes in network-level brain activity following stimulation during sleep, specifically in the beta-band path length, may predict improvements in metamemory. This highlights the potential for using brain stimulation to enhance metamemory and sheds new light on the neural mechanisms involved in memory processes.
NETWORK NEUROSCIENCE
(2021)
Article
Clinical Neurology
Francesca Miraglia, Carlo Tomino, Fabrizio Vecchio, Maurizio Gorgoni, Luigi De Gennaro, Paolo Maria Rossini
Summary: The study found that sleep deprivation altered brain network connectivity, especially in different frequency bands. Sleep deprivation affected the brain functional network structure, which may lead to impaired behavior and brain function.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Serap Aydin, Lara Onbasi
Summary: This study investigates the distinct psychophysiological and neural circuitry associated with fear and anger, despite their similar arousal-valence scores in emotion models. EEG data from OpenNeuro platform was analyzed using functional and effective connectivity estimators. Emotional states were classified using brain network measures and Long Short Term Memory Networks, with Partial Directed Coherence in Gamma sub-bands showing the best results. Fear and Anger were classified with an accuracy of 91.79%. Anger was found to have increased transitivity and decreased local efficiency compared to fear in the Gamma-band. Overall, PDC in short EEG epochs provides robust emotional indicators sensitive to affective sounds perception.
COGNITIVE NEURODYNAMICS
(2023)
Article
Engineering, Biomedical
Seyedeh Negin Seyed Fakhari, Foad Ghaderi, Mehdi Tehrani-Doost, Nasrollah Moghadam Charkari
Summary: This study investigates the effects of bumetanide treatment on brain connectivity in individuals with autism spectrum disorders. It suggests that bumetanide significantly alters brain connectivity, particularly in response to sad stimuli. These findings indicate that bumetanide may be a promising treatment for improving social interactions in individuals with autism, and that brain connectivity patterns can be used as a neural marker for developing new therapies.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2023)
Article
Clinical Neurology
Yanzhe Ning, Sisi Zheng, Sitong Feng, Hao Yao, Zhengtian Feng, Xinzi Liu, Linrui Dong, Hongxiao Jia
Summary: Acupuncture has been shown to improve sleep quality and cognitive function in individuals with insufficient sleep. This study found that acupuncture can modulate extensive brain networks and reverse the altered functional connectivity in individuals after acute sleep deprivation.
FRONTIERS IN NEUROLOGY
(2022)
Article
Psychiatry
Andjela Markovic, Michael Kaess, Leila Tarokh
Summary: Alterations in REM sleep have been observed in patients with psychiatric disorders. Recent work has shown that REM sleep plays a role in emotional processing and is affected by stress. This study examines the genetic and environmental factors contributing to REM sleep in adolescence and finds a strong genetic contribution, suggesting REM sleep neurophysiology as a potential endophenotype.
TRANSLATIONAL PSYCHIATRY
(2022)
Review
Anesthesiology
Dorine Lenoir, Barbara Cagnie, Helena Verhelst, Robby De Pauw
Summary: Chronic pain patients and healthy controls show differences in global graph measures, but conflicting evidence exists for certain global graph measures such as global efficiency, local efficiency, clustering coefficient, and HDI of degree. Significant correlations were found between several nodal and global graph measures and clinical outcomes related to pain, disability, and motor control. Further research is needed to validate the obtained findings and expand this knowledge to chronic pain populations not addressed in the included papers.
Article
Computer Science, Artificial Intelligence
Yanna Zhao, Mingrui Xue, Changxu Dong, Jiatong He, Dengyu Chu, Gaobo Zhang, Fangzhou Xu, Xinting Ge, Yuanjie Zheng
Summary: This article introduces an automatic seizure identification method based on brain connectivity learning, which demonstrates high performance and stability on different patients.
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
(2022)
Article
Computer Science, Interdisciplinary Applications
Berke Kilic, Serap Aydin
Summary: This study reveals a strong association between emotional arousal and neuro-functional brain connectivity measures. By classifying discrete emotional states and analyzing brain connectivity measures at different thresholds, the study finds that higher classification accuracies are achieved when using integration measures with specific thresholds and segment lengths.
Article
Physics, Multidisciplinary
Caterina Zanus, Aleksandar Miladinovic, Federica De Dea, Aldo Skabar, Matteo Stecca, Milos Ajcevic, Agostino Accardo, Marco Carrozzi
Summary: This preliminary study explored spindle-related connectivity as a possible biomarker for ADHD. The results showed significant differences in connectivity parameters between children with ADHD and healthy controls in different frequency bands, and Principal Component Analysis in the gamma band could distinguish ADHD from healthy subjects.
Article
Multidisciplinary Sciences
Vivien Reicher, Anna Kis, Peter Simor, Robert Bodizs, Marta Gacsi
Summary: The study investigated interhemispheric asymmetry in family dogs during afternoon naps using non-invasive polysomnography. The results showed left hemispheric predominance of slow frequency range during NREM sleep, with variations observed between different sleep recordings.
SCIENTIFIC REPORTS
(2021)
Article
Computer Science, Interdisciplinary Applications
Alberto Nogales, Alvaro J. Garcia-Tejedor, Pedro Chazarra, Arturo Ugalde-Canitrot
Summary: This study aims to use artificial intelligence and network analysis techniques to identify different brain states in children with epileptic spasms and explore their corresponding brain activity. Graph images of brain connectivity are used as input to a deep learning model for classification. The results show that this method can detect subtle differences in brain states and reveal the connectivity and network characteristics of the brain regions.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Psychology, Clinical
Unyoung Chavez-Baldini, Dorien H. Nieman, Amos Keestra, Anja Lok, Roel J. T. Mocking, Pelle de Koning, Valeria V. Krzhizhanovskaya, Claudi L. H. Bockting, Geeske van Rooijen, Dirk J. A. Smit, Arjen L. Sutterland, Karin J. H. Verweij, Guido van Wingen, Johanna T. W. Wigman, Nienke C. Vulink, Damiaan Denys
Summary: Cognitive deficits and psychopathology have independent but related dimensions, and interact in a transdiagnostic manner. Depressive and anxiety symptoms, verbal memory, and visual attention are especially relevant in this network. Future research should take a transdiagnostic approach, focusing on symptom-specific interactions with cognitive domains.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Clinical Neurology
Sophie M. D. D. Fitzsimmons, Ysbrand D. van der Werf, A. Dilene van Campen, Martijn Arns, Alexander T. Sack, Adriaan W. Hoogendoorn, Odile A. van den Heuvel
Summary: This study evaluated the efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) for obsessive-compulsive disorder (OCD) and ranked the relative efficacy of different stimulation protocols. The results showed that rTMS is effective for OCD compared to sham stimulation. Different stimulation protocols, such as low frequency right dorsolateral prefrontal cortex (dlPFC) stimulation, high frequency bilateral dlPFC stimulation, and low frequency pre-supplementary motor area (preSMA) stimulation, were all found to be efficacious. However, further studies are needed to explore the relative merits of these protocols.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Marthe E. Ford, Gert J. Geurtsen, Erny Groet, Radha D. Rambaran Mishre, Coen A. M. Van Bennekom, Eus J. W. Van Someren
Summary: This study demonstrates that blended CBT is an effective treatment for insomnia in individuals with acquired brain injury, regardless of cognitive and psychiatric symptoms. Online treatment has significant advantages in terms of availability and cost, and can contribute to the successful implementation of insomnia treatment for individuals with acquired brain injuries.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Lara Rosler, Glenn van Der Lande, Jeanne Leerssen, Roy Cox, Jennifer R. Ramautar, Eus J. W. van Someren
Summary: Actigraphy has been widely used as a cost-effective and easy-to-use tool for ambulatory sleep recording. However, there is little evidence to support the use of actigraphy in diagnosing or treating insomnia. This study found that actigraphy sleep estimates and circadian patterns failed to differentiate patients with insomnia from controls in the home environment, suggesting a need for alternative indicators of sleep quality in insomnia research.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Joy Perrier, Jessica Bruijel, Mikael Naveau, Jennifer Ramautar, Nicolas Delcroix, Joris Coppens, Oti Lakbila-Kamal, Diederick Stoffers, Nicolas Bessot, Eus J. W. Van Someren
Summary: Insomnia is associated with poor executive functioning. Functional connectivity differences were found in insomnia patients during the orienting and executive control processes compared to good sleepers. Insomniacs displayed weaker cortical connectivity during orienting and stronger connectivity during executive control. Reaction time was inversely correlated with connectivity differences.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Neurosciences
Ekaterina Koshmanova, Vincenzo Muto, Daphne Chylinski, Charlotte Mouraux, Mathilde Reyt, Martin Grinard, Puneet Talwar, Erik Lambot, Christian Berthomier, Marie Brandewinder, Nasrin Mortazavi, Christian Degueldre, Andre Luxen, Eric Salmon, Michel Georges, Fabienne Collette, Pierre Maquet, Eus Van Someren, Gilles Vandewalle
Summary: Insomnia disorder (ID) is a common neuropsychiatric disorder with significant socioeconomic burden. Understanding the genetic propensity for insomnia and sleep phenotypes in youth may lead to new treatments for the disease. This study found that there is an association between genetic risk factors for ID and reduced sleep quality and increased likelihood of daytime sleepiness.
NEUROBIOLOGY OF DISEASE
(2022)
Article
Medicine, Research & Experimental
J. E. Reesen, T. van der Zweerde, N. M. Batelaan, E. Fris, A. W. Hoogendoorn, S. Ikelaar, O. Lakbila-Kamal, J. Lancee, J. Leerssen, H. J. F. van Marle, F. van Nassau, P. van Oppen, A. van Straten, S. van Trigt, S. J. van der Wal, E. J. W. van Someren
Summary: This transdiagnostic randomized control trial evaluates the effects of guided internet-delivered cognitive behavioral therapy for insomnia on sleep quality and emotional distress. The study aims to improve sleep, reduce emotional symptoms, and enhance the effectiveness of regular treatment. The trial includes 576 participants and uses a randomized control design with a primary outcome measure of insomnia severity.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Neurosciences
Frans Schalkwijk, Eus J. W. Van Someren, Nelleke J. Nicolai, Julia L. Uijttewaal, Rick Wassing
Summary: A new line of insomnia research explores the developmental trajectories from early life stress to insomnia in adulthood. The findings indicate that adverse childhood experiences (ACE's) may lead to maladaptive coping styles and chronic hyperarousal or insomnia. The study also suggests that trauma and emotional processing should be considered in the treatment of insomnia.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Thiprawee Chattrattrai, Ghizlane Aarab, Tessa F. Blanken, Gabriel N. Pires, Alberto Herrero Babiloni, Cibele Dal Fabbro, Eus van Someren, Gilles Lavigne, Milton Maluly, Monica L. Andersen, Sergio Tufik, Frank Lobbezoo
Summary: This study investigated the associations of self-reported sleep bruxism with other sleep disorders and demographic, psychological, and lifestyle factors in the adult general population. The results showed that self-reported sleep bruxism was only significantly associated with sex, anxiety, and depression, while polysomnographically confirmed sleep bruxism was not associated with any of the included factors.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Roy Cox, Lara Rosler, Frederik D. Weber, Tessa F. Blanken, Rick Wassing, Jennifer R. Ramautar, Eus J. W. Van Someren
Summary: The nature and degree of objective sleep impairments in insomnia disorder are still unclear. Changes in sleep architecture on the first compared with subsequent nights in the laboratory further complicate this issue. There is mixed evidence regarding differential first-night effects in people with insomnia disorder and controls. This study aims to characterize insomnia- and night-related differences in sleep architecture. People with insomnia consistently had poorer sleep than controls on multiple variables during both nights. Although short sleep was more likely during the first night and in insomnia, a significant number of patients with insomnia no longer met this criterion on the second night, highlighting the importance of considering short-sleeping insomnia as a subtype.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Heloise Rach, Eve Reynaud, Ulker Kilic-Huck, Elisabeth Ruppert, Henri Comtet, Virginie Roy de Belleplaine, Fanny Fuchs, Eus J. W. Van Someren, Pierre A. A. Geoffroy, Patrice Bourgin
Summary: The absence of biomarkers makes it difficult to diagnose idiopathic hypersomnia and distinguish it from other central hypersomnia subtypes. By studying the retinal melanopsin-based pupil response, it was found that both idiopathic hypersomnia and narcolepsy type 1 patients had a reduced pupil response compared to controls. Additionally, basal pupil size was found to be a good discriminator between idiopathic hypersomnia and narcolepsy type 1.
JOURNAL OF SLEEP RESEARCH
(2023)
Editorial Material
Neurosciences
Anita Luthi, Paul Franken, Stephany Fulda, Francesca Siclari, Eus J. W. Van Someren
NATURE NEUROSCIENCE
(2023)
Article
Clinical Neurology
Frank Verkaik, Marthe E. E. Ford, Gert J. J. Geurtsen, Eus J. W. Van Someren
Summary: This study evaluated the role of sleep-related beliefs and behaviors in insomnia after acquired brain injury. The findings showed a significant correlation between these factors and insomnia severity. However, it was found that not all sleep-related beliefs and behaviors were inappropriate and maladaptive for the acquired brain injury population, but could reflect adequate observations and efforts in coping with the consequences of the brain damage.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Psychology, Clinical
Desana Kocevska, Isabel K. K. Schuurmans, Charlotte A. M. Cecil, Pauline W. W. Jansen, Eus J. W. van Someren, Annemarie I. I. Luik
Summary: Early life stress is strongly associated with poor sleep, and this association may start during prenatal development. This study investigates the longitudinal associations between prenatal psychosocial stress and childhood sleep, and examines whether prenatal stress interacts with genetic factors for poor sleep. The results show that prenatal stress is consistently related to sleep problems in children, and this association is exacerbated by genetic vulnerability for insomnia.
RESEARCH ON CHILD AND ADOLESCENT PSYCHOPATHOLOGY
(2023)
Article
Clinical Neurology
Tom Bresser, Jeanne Leerssen, Stefanie Hoelsken, Inge Groote, Jessica C. Foster-Dingley, Martijn P. van den Heuvel, Eus J. W. Van Someren
Summary: Insomnia poses a high risk for depression, and the effects of cognitive behavioural therapy on insomnia-related brain mechanisms are unclear. This longitudinal study suggests that individual differences in brain white matter microstructure at baseline may predict improvements in depressive symptoms, and interventions can affect white matter microstructure.
BRAIN COMMUNICATIONS
(2023)
