Article
Biology
Osnat Oz, Lior Matityahu, Aviv Mizrahi-Kliger, Alexander Kaplan, Noa Berkowitz, Lior Tiroshi, Hagai Bergman, Joshua A. Goldberg
Summary: The tonic activity of striatal cholinergic interneurons (CINs) is modified differentially by their afferent inputs, and the localization of active dendritic conductances in CIN dendrites may promote their differential responses to thalamic vs. cortical inputs.
Article
Neurosciences
Tiago Monteiro, Filipe S. Rodrigues, Margarida Pexirra, Bruno F. Cruz, Ana I. Goncalves, Pavel E. Rueda-Orozco, Joseph J. Paton
Summary: Temperature changes in the striatum affect neural activity and time judgments in rats, but not movement. The striatum may play a role in discrete decisions rather than continuous motor control.
NATURE NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Seong-Hwan Hwang, Yongsoo Ra, Somang Paeng, Hyoung F. Kim
Summary: A habitual gaze is crucial for efficiently identifying and exploiting valuable objects. Motivational salience plays a significant role in guiding habitual gaze choices, particularly the preference for negatively valued objects. These habitual choices can facilitate re-learning in a simulated value-forgotten condition.
Article
Multidisciplinary Sciences
Clara Rodriguez-Sabate, Manuel Rodriguez, Ingrid Morales
Summary: Two new recurrence plot methods were introduced to study the long-term dynamics and interactions between different brain regions. These methods were applied to compare interactions between patients with Parkinson's disease and healthy controls, revealing disruptions in interactions that may contribute to motor disorders and side effects of dopaminergic drugs.
Article
Neurosciences
Xiyuan Chen, Tianming Yang
Summary: The basal ganglia play a crucial role in decision making, with neurons reflecting the evidence accumulation process. A neural network model was created to study how the direct and indirect pathways of the basal ganglia interact in decision making, revealing their distinct influences on choices and reaction times.
COGNITIVE NEURODYNAMICS
(2021)
Article
Computer Science, Artificial Intelligence
Jian Song, Hui Lin, Shenquan Liu
Summary: This study constructed a spiking neural network based on basal ganglia anatomical data to investigate the decision-making mechanism of action selection. The results showed that inhibition and excitation play a role in action selection and explained the firing rate of GPi/SNr in the action-selection experiment.
NETWORK-COMPUTATION IN NEURAL SYSTEMS
(2023)
Article
Multidisciplinary Sciences
Emil Warnberg, Arvind Kumar
Summary: This article discusses the role of midbrain dopaminergic neurons in the basal ganglia and how to explain how dopamine supports learning of continuous outputs instead of discrete action values. The authors propose a model and demonstrate its validity through a learning rule.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Review
Neurosciences
Maja Klarendic, Diego Kaski
Summary: DBS treatment is widely used for movement disorders and other neurological and psychiatric conditions, with effects on eye movements dependent on stimulation location and underlying pathology. Understanding how DBS affects eye movements can provide insights into neural circuits involved in complex eye movement control. Further research is needed to explore the potential effects of DBS on eye movements with less common stimulation targets.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Xiaolu Wang, Zhiqiang Liu, Milen Angelov, Zhao Feng, Xiangning Li, Anan Li, Yan Yang, Hui Gong, Zhenyu Gao
Summary: The brain generates predictive motor commands for high-velocity movements, but how it organizes internal feedback for coordinating these movements is unclear. This study reveals a unique nucleo-olivary loop in the cerebellum that is involved in coordinating high-velocity movements. Activation of the excitatory nucleo-olivary pathway induces well-timed internal feedback signals in Purkinje cells, shaping cerebellar outputs. This pathway directly drives saccades and head movements while curtailing their amplitude and velocity through internal feedback.
NATURE NEUROSCIENCE
(2023)
Editorial Material
Clinical Neurology
Shanyu Pi, Qiuxiang Li, Jing Li, Hongyu Long, Bo Xiao
Summary: A 14-year-old girl presented with acute ascending, symmetric numbness, and flaccid paralysis 3 weeks after a suspected gastrointestinal infection. She had experienced anorexia since this gastrointestinal episode. EMG showed a sensorimotor axonal polyneuropathy. Routine CSF analysis and serum-specific antibodies were all negative. Brain MRI showed bilateral symmetric basal ganglia lesions. A more thorough and detailed history indicated exercise intolerance, and specific examinations subsequently revealed an underlying etiology.
Article
Multidisciplinary Sciences
Esther Vinner Harduf, Ayala Matzner, Katya Belelovsky, Izhar Bar-Gad
Summary: The study demonstrates a reduction in tic expression during sleep in an animal model of chronic tic disorders and investigates the underlying neural mechanism. The findings point towards a possible mechanism for the modulation of tic expression in patients with TS during sleep and potentially during other behavioral states.
Article
Neurosciences
Richard Gast, Ruxue Gong, Helmut Schmidt, Hil G. E. Meijer, Thomas R. Knoesche
Summary: The study explores how pallidal heterogeneity influences dynamic regimes in the GPe and its response to oscillatory input. It suggests that changes in intrapallidal connectivity can lead to different dynamic behaviors in the GPe, and proposes hypotheses on how dopamine depletion may affect neural rhythms in the GPe. This research has implications for understanding the role of GPe in neurological disorders such as Parkinson's disease.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Rong Li, Ting Zou, Xuyang Wang, Hongyu Wang, Xiaofei Hu, Fangfang Xie, Li Meng, Huafu Chen
Summary: Parkinson's disease is a progressive neurodegenerative disease characterized by both motor and non-motor symptoms. Research suggests that as the disease progresses, gray matter atrophy in Parkinson's patients spreads from the basal ganglia to other brain regions, potentially playing a key role in motor and non-motor circuits.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Andrea Stocco, Catherine Sibert, Zoe Steine-Hanson, Natalie Koh, John E. Laird, Christian J. Lebiere, Paul Rosenbloom
Summary: The study analyzed functional MRI data to reveal the connection between the CMC architecture and human brain function, finding that CMC outperformed other models in various cognitive domains and tasks. These results suggest that a common set of architectural principles underpins both human brain function and artificial intelligence.
Article
Multidisciplinary Sciences
Tomiko Takeuchi, Hisami Aoyagi, Yoshimi Kuwako, Isao Hozumi
Summary: This study aims to identify the experiences of patients with PDGFB variants of primary brain calcification after diagnosis. Semi-structured interviews were conducted with five patients over the age of 21 for three years. The results revealed seven categories, 15 subcategories, and 129 codes, including shock at hearing the term 'brain calcification' for the first time, anxiety regarding the risk of heredity, anxiety along with severe headaches and various other symptoms, gratitude for family members who care, accepting the disease as a non-life-threatening illness, feeling alienated due to the rare and intractable disease, and modifying lifestyle due to the illness.
Article
Multidisciplinary Sciences
Alfred O. Effenberg, Gerd Schmitz
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2018)
Article
Multidisciplinary Sciences
Shashank Ghai, Gerd Schmitz, Tong-Hun Hwang, Alfred O. Effenberg
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2019)
Article
Neurosciences
Gerd Schmitz, Mirco Dierking, Anthea Guenther
EXPERIMENTAL BRAIN RESEARCH
(2018)
Article
Chemistry, Multidisciplinary
Ursula Fehse, Gerd Schmitz, Daniela Hartwig, Shashank Ghai, Heike Brock, Alfred O. Effenberg
APPLIED SCIENCES-BASEL
(2020)
Article
Neurosciences
Dari Trendafilov, Gerd Schmitz, Tong-Hun Hwang, Alfred O. Effenberg, Daniel Polani
FRONTIERS IN HUMAN NEUROSCIENCE
(2020)
Article
Orthopedics
Julia Reh, Gerd Schmitz, Tong-Hun Hwang, Alfred O. Effenberg
Summary: The study investigates the effect of volume on auditory feedback for gait pattern and direction, and its interaction with pitch. The results suggest that modifying the volume of auditory feedback can be an effective way to improve gait symmetry, particularly for patients with limited gait improvement based on verbal corrections and conscious motor control.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Neurosciences
Manfred A. Mueller, Antonieta Martinez-Guerrero, Maria Corsi-Cabrera, Alfred O. O. Effenberg, Armin Friedrich, Ignacio Garcia-Madrid, Matthias Hornschuh, Gerd Schmitz, Markus F. F. Mueller
Summary: This study found that an appropriate acoustic environment can improve the interaction between soccer teammates, leading to increased connectivity and scoring rate in male teams. Surprisingly, female teams did not show any improvement under the same conditions. The study also revealed that the acoustic rhythm can modulate participants' attention level, with distinct tempo preferences and gender differences.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Gerd Schmitz
Summary: This study found that visuomotor adaptation training may have a positive impact on cognitive performance.
Article
Sport Sciences
Julia Reh, Gerd Schmitz, Tong-Hun Hwang, Alfred O. Effenberg
Summary: Gait sonification training can improve the gait pattern of patients after unilateral hip arthroplasty, reduce the load on the musculoskeletal system, and shorten the rehabilitation time.
FRONTIERS IN SPORTS AND ACTIVE LIVING
(2021)
Article
Environmental Sciences
Gerd Schmitz
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Psychology, Educational
Gerd Schmitz, Jakob M. Meis, Matthias Hafferkama, Sabine Schmitz
JOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES
(2020)
Meeting Abstract
Ophthalmology
Alfred O. Effenberg, Shashank Ghai, Tonghun Hwang, Gerd Schmitz
Article
Neurosciences
Julia Reh, Tong-Hun Hwang, Gerd Schmitz, Alfred O. Effenberg
Article
Psychology, Multidisciplinary
Tong-Hun Hwang, Gerd Schmitz, Kevin Klemmt, Lukas Brinkop, Shashank Ghai, Mircea Stoica, Alexander Maye, Holger Blume, Alfred O. Effenberg
FRONTIERS IN PSYCHOLOGY
(2018)
Article
Sport Sciences
Gerd Schmitz, Lena Sommer
BEWEGUNGSTHERAPIE UND GESUNDHEITSSPORT
(2020)