The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder

So depression is an inflammatory disease, but where does the inflammation come from?

(2016) Michael Berk et al.   BMC Medicine

Integrative mouse and human mRNA studies using WGCNA nominates novel candidate genes involved in the pathogenesis of major depressive disorder

(2013) Karim Malki et al.   PHARMACOGENOMICS

Early and late onset, first-episode, treatment-naive depression: same clinical symptoms, different regional neural activities

(2012) Jin-dong Chen et al.   JOURNAL OF AFFECTIVE DISORDERS

A mega-analysis of genome-wide association studies for major depressive disorder

(2012)   MOLECULAR PSYCHIATRY

Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression

(2012) Karim Malki et al.   Pharmacogenetics and Genomics

Stressor-Like Effects of c-Jun N-Terminal Kinase (JNK) Inhibition

(2012) Melanie Clarke et al.   PLoS One

Pharmacoproteomic investigation into antidepressant response in two mouse inbred strains

(2012) Karim Malki et al.   PROTEOMICS

Genetic Predictors of Response to Serotonergic and Noradrenergic Antidepressants in Major Depressive Disorder: A Genome-Wide Analysis of Individual-Level Data and a Meta-Analysis

(2012) Katherine E. Tansey et al.   PLOS MEDICINE

Childhood Maltreatment Predicts Unfavorable Course of Illness and Treatment Outcome in Depression: A Meta-Analysis

(2011) Valentina Nanni et al.   AMERICAN JOURNAL OF PSYCHIATRY

Expression of VGluT1 and VGAT mRNAs in human dorsolateral prefrontal cortex during development and in schizophrenia

(2011) Samantha J. Fung et al.   BRAIN RESEARCH

Silencing of 14-3-3ζ over-expression in hepatocellular carcinoma inhibits tumor growth and enhances chemosensitivity to cis-diammined dichloridoplatium

(2011) Jung Eun Choi et al.   CANCER LETTERS

MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy

(2011) Zheng Zhang et al.   FEBS LETTERS

Identification of miR-193b Targets in Breast Cancer Cells and Systems Biological Analysis of Their Functional Impact

(2011) Suvi-Katri Leivonen et al.   MOLECULAR & CELLULAR PROTEOMICS

Antidepressants and the resilience to early-life stress in inbred mouse strains

(2011) Elke Binder et al.   Pharmacogenetics and Genomics

Gene–Environment Interaction in Major Depression and Antidepressant Treatment Response

(2011) Robert Keers et al.   Current Psychiatry Reports

Convergent Animal and Human Evidence Suggests a Role of PPM1A Gene in Response to Antidepressants

(2010) Karim Malki et al.   BIOLOGICAL PSYCHIATRY

Molecular evidence that cortical synaptic growth predominates during the first decade of life in humans

(2010) Maree J. Webster et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP

(2010) Robert Keers et al.   JOURNAL OF AFFECTIVE DISORDERS

Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models

(2010) B M Andrus et al.   MOLECULAR PSYCHIATRY

Regulation of cytoskeleton machinery, neurogenesis and energy metabolism pathways in a rat gene-environment model of depression revealed by proteomic analysis

(2010) C. Piubelli et al.   NEUROSCIENCE

Expression Profiling of a Genetic Animal Model of Depression Reveals Novel Molecular Pathways Underlying Depressive-Like Behaviours

(2010) Ekaterini Blaveri et al.   PLoS One

Early-life stress and antidepressants modulate peripheral biomarkers in a gene–environment rat model of depression

(2010) Lucia Carboni et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Beyond the serotonin hypothesis: Mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders

(2010) Ann Gardner et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

Increased stress-evoked nitric oxide signalling in the Flinders sensitive line (FSL) rat: a genetic animal model of depression

(2009) Gregers Wegener et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Genetic predictors of response to antidepressants in the GENDEP project

(2009) Rudolf Uher et al.   PHARMACOGENOMICS JOURNAL

Upregulation of NRG-1 and VAMP-1 in human brain aggregates exposed to clozapine

(2009) Gursharan Chana et al.   SCHIZOPHRENIA RESEARCH

Maternal Care and Hippocampal Plasticity: Evidence for Experience-Dependent Structural Plasticity, Altered Synaptic Functioning, and Differential Responsiveness to Glucocorticoids and Stress

(2008) D. L. Champagne et al.   JOURNAL OF NEUROSCIENCE

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression

(2008) Michael Maes et al.   METABOLIC BRAIN DISEASE

A genetic rat model of depression, Flinders sensitive line, has a lower density of 5-HT1A receptors, but a higher density of 5-HT1B receptors, compared to control rats

(2008) Kyoko Nishi et al.   NEUROCHEMISTRY INTERNATIONAL

HPA Axis Reactivity: A Mechanism Underlying the Associations Among 5-HTTLPR, Stress, and Depression

(2007) Ian H. Gotlib et al.   BIOLOGICAL PSYCHIATRY