期刊
BMC MEDICINE
卷 11, 期 -, 页码 -出版社
BMC
DOI: 10.1186/1741-7015-11-143
关键词
Angiogenesis; Arteriogenesis; Coronary artery disease; Coronary collateral circulation
资金
- Swiss National Science Foundation SNF
- Swiss Heart Foundation
- BartsHealth Cardiovascular Biomedical Research Unit
- National Institute for Health Research
The coronary arteries have been regarded as end arteries for decades. However, there are functionally relevant anastomotic vessels, known as collateral arteries, which interconnect epicardial coronary arteries. These vessels provide an alternative source of blood supply to the myocardium in cases of occlusive coronary artery disease. The relevance of these collateral arteries is a matter of ongoing debate, but increasing evidence indicates a relevant protective role in patients with coronary artery disease. The collateral circulation can be assessed by different methods; the gold standard involves intracoronary pressure measurements. While the first clinical trials to therapeutically induce growth of collateral arteries have been unavailing, recent pilot studies using external counterpulsation or growth factors such as granulocyte colony stimulating factor (G-CSF) have shown promising results.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据