Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes

Gene-Diet Interactions in Childhood Obesity

(2012) William S. Garver   CURRENT GENOMICS

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

The role of decreased levels of Niemann-Pick C1 intracellular cholesterol transport on obesity is reversed in the C57BL/6J, metabolic syndrome mouse strain: a metabolic or an inflammatory effect?

(2012) Ivan Borbon et al.   JOURNAL OF APPLIED GENETICS

Convergent Evolution of Escape from Hepaciviral Antagonism in Primates

(2012) Maulik R. Patel et al.   PLOS BIOLOGY

Filovirus Tropism: Cellular Molecules for Viral Entry

(2012) Ayato Takada   Frontiers in Microbiology

Influence of Physical Inactivity on Associations Between Single Nucleotide Polymorphisms and Genetic Predisposition to Childhood Obesity

(2011) B. Xi et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The Niemann-Pick C1 gene interacts with a high-fat diet and modifying genes to promote weight gain

(2011) David Jelinek et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

GeCo++: a C++ library for genomic features computation and annotation in the presence of variants

(2011) M. Cereda et al.   BIOINFORMATICS

Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (riyadh cohort 2): a decade of an epidemic

(2011) Nasser M Al-Daghri et al.   BMC Medicine

Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration

(2011) Manuel Alejandro Fernández-Rojo et al.   HEPATOLOGY

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

(2011) Mariel M Finucane et al.   LANCET

A Random Effects Branch-Site Model for Detecting Episodic Diversifying Selection

(2011) Sergei L. Kosakovsky Pond et al.   MOLECULAR BIOLOGY AND EVOLUTION

SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians

(2011) Yan Dong et al.   MOLECULAR GENETICS AND METABOLISM

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

(2011) Tuomas O Kilpeläinen et al.   NATURE GENETICS

Studies of Metabolic Phenotypic Correlates of 15 Obesity Associated Gene Variants

(2011) Camilla Helene Sandholt et al.   PLoS One

Evolutionary Adaptations to Dietary Changes

(2010) F. Luca et al.   Annual Review of Nutrition

Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

(2010) W. Delport et al.   BIOINFORMATICS

Associations of Six Single Nucleotide Polymorphisms in Obesity-Related Genes With BMI and Risk of Obesity in Chinese Children

(2010) L. Wu et al.   DIABETES

Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance

(2010) D. Jelinek et al.   HUMAN MOLECULAR GENETICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Paleovirology—Modern Consequences of Ancient Viruses

(2010) Michael Emerman et al.   PLOS BIOLOGY

Unexpected Inheritance: Multiple Integrations of Ancient Bornavirus and Ebolavirus/Marburgvirus Sequences in Vertebrate Genomes

(2010) Vladimir A. Belyi et al.   PLoS Pathogens

Polymorphisms of the Scavenger Receptor Class B Member 1 Are Associated with Insulin Resistance with Evidence of Gene by Sex Interaction

(2009) Jeanette J. McCarthy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Evolutionary Fingerprinting of Genes

(2009) S. L. Kosakovsky Pond et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Decreased Npc1 Gene Dosage in Mice Is Associated With Weight Gain

(2009) David Jelinek et al.   Obesity

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

(2009) Matthew W. McNatt et al.   PLoS Pathogens

Rapid Evolution by Positive Darwinian Selection in T-Cell Antigen CD4 in Primates

(2008) Zhengdong D. Zhang et al.   JOURNAL OF MOLECULAR EVOLUTION

Protein kinase R reveals an evolutionary model for defeating viral mimicry

(2008) Nels C. Elde et al.   NATURE

Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

(2008) Julie A. Kerns et al.   PLoS Genetics

Patterns of Positive Selection in Six Mammalian Genomes

(2008) Carolin Kosiol et al.   PLoS Genetics