Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers

Different expression of EZH2, BMI1 and Ki67 in low and high grade neuroendocrine tumors of the lung

(2017) Anna-Louise Reinert Ørsum Bondgaard et al.   Cancer Biomarkers

The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

(2012) Catharina Medrek et al.   BMC CANCER

Molecular subtype is determinant on inflammatory status and immunological profile from invasive breast cancer patients

(2012) A. C. S. A. Herrera et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

(2012) M. Velasco-Velazquez et al.   CANCER RESEARCH

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Clinical and biological relevance of enhancer of zeste homolog 2 in triple-negative breast cancer

(2012) Yaser R. Hussein et al.   HUMAN PATHOLOGY

Pharmacokinetic Optimization of Class-Selective Histone Deacetylase Inhibitors and Identification of Associated Candidate Predictive Biomarkers of Hepatocellular Carcinoma Tumor Response

(2012) Jason C. Wong et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

ArrayExpress update—trends in database growth and links to data analysis tools

(2012) Gabriella Rustici et al.   NUCLEIC ACIDS RESEARCH

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent

(2012) K. Xu et al.   SCIENCE

The Cancer Stem Cell Subtype Determines Immune Infiltration of Glioblastoma

(2012) Christoph P. Beier et al.   STEM CELLS AND DEVELOPMENT

Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1

(2012) Lauren Averett Byers et al.   Cancer Discovery

EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR

(2011) C. Wang et al.   CANCER RESEARCH

EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes  -Catenin-Dependent Hepatocarcinogenesis

(2011) A. S. L. Cheng et al.   CANCER RESEARCH

Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker

(2011) Masashi Takawa et al.   CANCER SCIENCE

3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells

(2011) Tetsuhiro Chiba et al.   INTERNATIONAL JOURNAL OF CANCER

HDAC4 Protein Regulates HIF1α Protein Lysine Acetylation and Cancer Cell Response to Hypoxia

(2011) Hao Geng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers

(2011) Shuet Theng Lee et al.   MOLECULAR CELL

A pharmacogenomic method for individualized prediction of drug sensitivity

(2011) A. L. Cohen et al.   Molecular Systems Biology

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Histone deacetylase 1 is required for transforming growth factor-β1-induced epithelial–mesenchymal transition

(2010) Weiwei Lei et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables

(2010) Sitharthan Kamalakaran et al.   Molecular Oncology

Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells

(2010) T. Angrisano et al.   NUCLEIC ACIDS RESEARCH

Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma

(2009) Li-Ru He et al.   BMC CANCER

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

HDAC4 inhibits cell-cycle progression and protects neurons from cell death

(2008) Nazanin Majdzadeh et al.   Developmental Neurobiology

A Precisely Regulated Gene Expression Cassette Potently Modulates Metastasis and Survival in Multiple Solid Cancers

(2008) Kun Yu et al.   PLoS Genetics