Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C

Protein degradation and iron homeostasis

(2012) Joel W. Thompson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulation and function of mammalian DNA methylation patterns: a genomic perspective

(2012) H. Wu et al.   Briefings in Functional Genomics

Enhancers: emerging roles in cell fate specification

(2012) Chin-Tong Ong et al.   EMBO REPORTS

A novel c.2T > C mutation of the KDM5C/JARID1C gene in one large family with X-linked intellectual disability

(2012) Katrin Õunap et al.   European Journal of Medical Genetics

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Population-specificity of human DNA methylation

(2012) Hunter B Fraser et al.   GENOME BIOLOGY

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

(2011) Wei Xu et al.   CANCER CELL

Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells

(2011) Oren Ram et al.   CELL

The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo

(2011) Toshiro Moroishi et al.   Cell Metabolism

Exome sequencing and the genetics of intellectual disability

(2011) S Topper et al.   CLINICAL GENETICS

Assessment of methylation level prediction accuracy in methyl-DNA immunoprecipitation and sodium bisulfite based microarray platforms

(2011) Rageen Rajendram et al.   Epigenetics

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

(2011) Juan Sandoval et al.   Epigenetics

Sequence overlap between autosomal and sex-linked probes on the Illumina HumanMethylation27 microarray

(2011) Yi-an Chen et al.   GENOMICS

DNA Methylation as a Biomarker for Neuropsychiatric Diseases

(2011) Sanxi Ai et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Autism Spectrum Disorders and Epigenetics

(2011) Daria Grafodatskaya et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

A novel nonsense mutation in KDM5C/JARID1C gene causing intellectual disability, short stature and speech delay

(2011) Cíntia B. Santos-Rebouças et al.   NEUROSCIENCE LETTERS

Epigenetic cancer therapy: rationales, targets and drugs

(2011) M Rius et al.   ONCOGENE

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

(2011) Jason Gertz et al.   PLoS Genetics

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

(2011) Jordana T Bell et al.   GENOME BIOLOGY

Genetic Control of Individual Differences in Gene-Specific Methylation in Human Brain

(2010) Dandan Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prader-Willi syndrome and Angelman syndrome

(2010) Karin Buiting   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Ubiquitination in Postsynaptic Function and Plasticity

(2010) Angela M. Mabb et al.   Annual Review of Cell and Developmental Biology

Genetics of Early Onset Cognitive Impairment

(2010) Hans Hilger Ropers   Annual Review of Genomics and Human Genetics

The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature

(2010) Jianhua Zhao et al.   BMC Medical Genetics

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Reversible histone methylation regulates brain gene expression and behavior

(2010) Jun Xu et al.   HORMONES AND BEHAVIOR

The JmjN Domain of Jhd2 Is Important for Its Protein Stability, and the Plant Homeodomain (PHD) Finger Mediates Its Chromatin Association Independent of H3K4 Methylation

(2010) Fu Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Ubiquitination of β-Catenin by Siah-1 and Regulation by the Exchange Factor TBL1

(2010) Yoana N. Dimitrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The genetic basis of non-syndromic intellectual disability: a review

(2010) Liana Kaufman et al.   Journal of Neurodevelopmental Disorders

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

Disruption of the epigenetic code: An emerging mechanism in mental retardation

(2010) Hans van Bokhoven et al.   NEUROBIOLOGY OF DISEASE

Molecular coupling of DNA methylation and histone methylation

(2010) Hideharu Hashimoto et al.   Epigenomics

Altered DNA Methylation in Leukocytes with Trisomy 21

(2010) Kristi Kerkel et al.   PLoS Genetics

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain

(2009) Junji Otani et al.   EMBO REPORTS

Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype–phenotype correlation

(2009) Sinitdhorn Rujirabanjerd et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

(2009) David N. Ciccone et al.   NATURE

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

(2009) Joseph T. Glessner et al.   NATURE

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

MAP'ing CNS Development and Cognition: An ERKsome Process

(2009) Ivy S. Samuels et al.   NEURON

The N-terminus of histone H3 is required for de novo DNA methylation in chromatin

(2009) Jia-Lei Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis

(2009) A. A. Salahudeen et al.   SCIENCE

Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase

(2009) A. A. Vashisht et al.   SCIENCE

A novel mutation inJARID1C/SMCX in a patient with autism spectrum disorder (ASD)

(2008) Abidemi Adegbola et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The emerging functions of histone demethylases

(2008) Karl Agger et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

XLMR genes: update 2007

(2008) Pietro Chiurazzi et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Failure of neuronal homeostasis results in common neuropsychiatric phenotypes

(2008) Melissa B. Ramocki et al.   NATURE

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

(2008) Silvina Epsztejn-Litman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sex-Specific Expression of the X-Linked Histone Demethylase Gene Jarid1c in Brain

(2008) Jun Xu et al.   PLoS One

Escape from X chromosome inactivation is an intrinsic property of the Jarid1c locus

(2008) N. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity

(2008) M. Ohtsubo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA