Article
Pharmacology & Pharmacy
Abraham Tolley, Kirpal Grewal, Alessa Weiler, Anna Maria Papameletiou, Refaat Hassan, Saurav Basu
Summary: This study found that poor medication adherence among adults with NCDs in India is influenced by multiple factors, with socioeconomic and health-system factors being the main contributors. Future interventions should focus on addressing barriers related to multimorbidity, comorbid depression and anxiety, and low educational status.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Health Care Sciences & Services
Kanya Anindya, Nawi Ng, Rifat Atun, Tiara Marthias, Yang Zhao, Barbara McPake, Alexander van Heusden, Tianxin Pan, John Tayu Lee
Summary: Multimorbidity is associated with higher healthcare utilization and out-of-pocket expenditure, especially among those in the upper tail of the distribution. Health financing strategies are urgently needed to meet the needs of patients with multimorbidity.
BMC HEALTH SERVICES RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
S. Goli, Moradhvaj, J. Pradhan, T. Reja
Summary: The study found that out-of-pocket expenditures on institutional deliveries in India have significantly increased from 2004 to 2017/18, despite the introduction of conditional cash transfer incentives. The results indicate that most states experienced a substantial raise in out-of-pocket expenditures for institutional deliveries even with the JSY program.
Article
Public, Environmental & Occupational Health
Parul Puri, Sanghamitra Pati
Summary: The study investigates the magnitude and correlates of non-communicable disease multimorbidity and explores its linkages with health care utilization and out-of-pocket expenditure among aboriginal or tribal older adults. The findings suggest that higher age, Muslim religion, higher education, unemployment, and affluent background were the major correlates of multimorbidity. Measures need to be taken to assess the multimorbidity burden and reduce health care expenditure, ensuring health equity among country's vulnerable population.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Marina J. MacKinnon, Camila A. Picchio, Daniel K. Nomah, Ariadna Rando Segura, Lena van Selm, Emma Fernandez, Maria Buti, Sabela Lens, Xavier Forns, Sergio Rodriguez-Tajes, Javier Pamplona, Carmen Lopez, Francisco Rodriguez-Frias, Jeffrey V. Lazarus
Summary: This study aimed to determine the prevalence and risk factors of chronic conditions among West African migrants in Barcelona, Spain, and investigate the relationship between years of residence and disease burden. The results showed that the prevalence of hepatitis B virus, non-communicable diseases, metabolic risk factors, and multimorbidity was 9.17%, 20.87%, and 4.13% respectively. Factors associated with these conditions included male gender, previous HBV testing, living in Spain for more than 5 years, being female, and being aged 50 years or older. These findings highlight the importance of early detection and tailored public health interventions for migrant populations to reduce the disease burden.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Health Care Sciences & Services
Mehak Nanda, Rajesh Sharma
Summary: More than 50% of health expenditure in India is paid out-of-pocket, imposing a huge financial burden on households. This study examines the economic impact of out-of-pocket health expenditure across 17 disease categories in India, revealing that 49% of households seeking hospitalization and/or outpatient care experienced catastrophic health expenditure, while 15% fell below the poverty line due to out-of-pocket payments.
HEALTH POLICY AND PLANNING
(2023)
Article
Health Care Sciences & Services
Shalem Balla, Md Illias Kanchan Sk, Mayanka Ambade, Babul Hossain
Summary: This study reveals that the cost of maternity care in many states of India, particularly delivery care expenses, is very high. The study suggests increasing subsidized maternity care facilities to alleviate households' catastrophic maternity expenditure.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Oncology
Mohammad A. Karim, Amit G. Singal, Robert L. Ohsfeldt, Michael A. Morrisey, Hye-Chung Kum
Summary: The study highlights that many insured non-elderly cancer survivors allocate a substantial portion of their out-of-pocket expenditure for healthcare services, with nearly 8.8% facing underinsurance. Utilization of healthcare services varies across different sociodemographic groups.
Article
Public, Environmental & Occupational Health
Yuehua Chen, Wenbin Liu
Summary: This study investigated the determinants of primary care utilization and out-of-pocket expenses among multimorbid elderly individuals. The results showed that factors such as gender, marital status, residential area, self-rated health, education level, and household economy significantly influenced the utilization of primary care and out-of-pocket expenses.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Guvenc Kockaya, Gulpembe Oguzhan, Selin Okcun, Mustafa Kurnaz
Summary: This study aimed to determine the out-of-pocket health expenditures of households in Turkey where individuals with rare diseases are residing. A total of 439 participants were included in the analysis. Special nutrition was found to be the highest expenditure group and emergency departments were the lowest expenditure group.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Health Care Sciences & Services
Chee Hui Liew, Fatiha Hana Shabaruddin, Maznah Dahlui
Summary: This study estimated the economic burden on gynaecological cancer patients and their households, showing the out-of-pocket expenditure, catastrophic health expenditure (CHE), and poverty impact. The study found that low-income households and patients receiving chemotherapy were more likely to face catastrophic health expenditure.
Article
Public, Environmental & Occupational Health
Melkamu Alemayehu, Banchlay Addis, Tsega Hagos
Summary: This study aimed to assess the out-of-pocket health expenditure and associated factors among adult patients with hypertension in Debre-Tabor Comprehensive Specialized Hospital. The results showed that the out-of-pocket health expenditure was high among adult patients with hypertension and was significantly associated with sex, wealth status, distance from hospital, comorbidity, health insurance, and number of visits. It is recommended that the Ministry of Health, regional health bureaus, and other stakeholders strengthen early detection and prevention strategies for comorbidities in hypertensive patients, promote health insurance coverage, and provide better medication subsidies for the poor.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Multidisciplinary Sciences
Kamal Gholipour, Sama Behpaie, Shabnam Iezadi, Akbar Ghiasi, Jafar Sadegh Tabrizi
Summary: This study aimed to investigate the costs of hospital care for patients with COVID-19 and the amount of out-of-pocket payments. The results showed that COVID-19 disease imposed a high cost of hospitalization, mainly due to the cost of hospital beds/day of routine services. The study also highlighted the negative impact of using different methods for cost calculation on the comparability of studies.
Article
Economics
Xue Li, Russell Smyth, Yao Yao
Summary: We estimate the causal effect of extreme temperatures on out-of-pocket medical expenditure using data from three waves of China Family Panel Studies. Both extreme cold and extreme heat increase expenditure, with hot days having a larger effect. Extreme temperatures lead to sedentary activities, sleep disruption, and energy poverty, negatively impacting physical and mental health. Combining our estimates with temperature projections, we find that out-of-pocket medical expenditure is projected to increase in the future, depending on greenhouse gas emissions.
CHINA ECONOMIC REVIEW
(2023)
Article
Immunology
Sehr Brar, Gunjeet Kaur, Malaisamy Muniyandi, Nagarajan Karikalan, Henna Bano, Anil Bhansali, Sanjay Jain, Savita Kumari, Shankar Prinja
Summary: This study assessed the cost of screening for diabetes and hypertension, as well as the out-of-pocket expenditure and health-related quality of life among patients. The findings suggest that the cost of screening per person is $45.2, and patients face high outpatient costs and medical expenses. The results of the study are useful for evaluating the cost-effectiveness of screening for diabetes and hypertension.
INDIAN JOURNAL OF MEDICAL RESEARCH
(2023)
Article
Environmental Sciences
Krushna Chandra Sahoo, Girish Chandra Dash, Subhashree Panda, Jaya Singh Kshatri, Azhar Uddin, Matrujyoti Pattnaik, Rakesh Kumar Sahoo, Rinshu Diwedi, Subrat Kumar Palo, Debdutta Bhattacharya, Sanghamitra Pati
Summary: The use of renewable energy has a positive impact on women's health and quality of life, reducing the risk of diseases such as ophthalmic disorders, asthma, and acute lower respiratory infections.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Bipasa Kar, Chanakya Nath Kundu, Sanghamitra Pati, Debdutta Bhattacharya
Summary: Amid the rise of multi-drug resistance, finding new antibiotics is challenging. This study utilized molecular docking to screen and identify three phytocompounds with potential antimicrobial activity, outperforming the reference drug meropenem. The compounds showed competitive inhibition against the target proteins and demonstrated stability through molecular dynamics simulations. These findings suggest that the phytocompounds have potential as Metallo beta-lactamase inhibitors and warrant further in vitro and in vivo clinical trials.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Biochemistry & Molecular Biology
Budheswar Dehury, Sarbani Mishra, Sanghamitra Pati
Summary: The spread of different SARS-CoV-2 variants highlights the importance of understanding the structural properties of its proteins. This study reveals the structural dynamics of M-PRO, an attractive drug target for antiviral treatments, and identifies stable and compact conformations with intact catalytic sites and structural integrity.
JOURNAL OF CELLULAR BIOCHEMISTRY
(2023)
Review
Multidisciplinary Sciences
Pranita Patsani, Jayashree Parida, Arpita Panda, Susangita Jena, Swati Sukalyani Behera, Abinash Pradhan, Prasanna Kumar Patra, Sanghamitra Pati, Harpreet Kaur, Subhendu Kumar Acharya
Summary: This article aims to understand the current knowledge, beliefs, and practices among Indian adolescents regarding HIV/AIDS through a systematic scoping review. The study will use an effective methodology for literature search and assess the quality of relevant studies. This article is of great significance to healthcare professionals and policy makers.
Article
Multidisciplinary Sciences
Rahul K. Gajbhiye, Itta Krishna Chaaithanya, Hrishikesh Munshi, Ranjan Kumar Prusty, Amarendra Mahapatra, Subrata Kumar Palo, Sanghamitra Pati, Arun Yadav, Manohar Bansode, Shashikant Shambharkar, Kanna Madavi, Himmatrao S. Bawaskar, Smita D. Mahale
Summary: India is the snakebite capital of the world, yet there is limited information on awareness and knowledge about snakebite. The National Snakebite Project aims to build capacity in the healthcare system and empower communities in preventing and managing snakebite envenomation. Through a multi-sectoral approach and five phases of research and intervention, the project seeks to reduce the burden of snakebite and provide critical inputs for revising the National Snakebite Treatment protocol.
Article
Multidisciplinary Sciences
Jogesh Murmu, Ritik Agrawal, Sayantani Manna, Sweta Pattnaik, Shishirendu Ghosal, Abhinav Sinha, Ardhendu Sekhar Acharya, Srikanta Kanungo, Sanghamitra Pati
Summary: This study examines the prevalence and determinants of tobacco use among older tribal adults in India. The results show a high burden of tobacco use among this population, with socioeconomic factors and regional differences playing a significant role. These findings have important implications for tobacco control programs and targeted health education for indigenous communities.
Article
Public, Environmental & Occupational Health
Bhavna Bharati, Kirti Sundar Sahu, Sanghamitra Pati
Summary: This study used data from the Longitudinal Aging Study in India (LASI) to investigate the overall prevalence of smokeless tobacco use, as well as its association with different occupations and related variables. The findings showed significant associations between smokeless tobacco use and factors such as occupation type, employer type, workplace, business type, and workload. The government should focus on implementing deaddiction and tobacco quitting policies targeting rural male informal workers.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Chandrakant Lahariya, Krushna Chandra Sahoo, T. Sundararaman, Shankar Prinja, Kavitha Rajsekhar, Sanghamitra Pati
Summary: In India, there is a renewed focus on Universal Health Coverage (UHC) and Health Technology Assessment (HTA) as an important tool for advancing UHC. The development and application of HTA in India, including capacity building and establishment of institutional mechanisms, are emphasized. Lessons learned and future steps are discussed within the context of utilizing HTA approach in the Ayushman Bharat program. The importance of selecting and implementing effective technologies and interventions within national health systems, given limited resources, highlights the need for enhanced national capacity, information exchange, and collaborative approaches.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Public, Environmental & Occupational Health
Krushna Chandra Sahoo, Sapna Negi, Pranab Mahapatra, Kajal Samantaray, Girish Chandra Dash, Shubhankar Dubey, Mili Roopchand Sahay, Rakesh Kumar Sahoo, Debdutta Bhattacharya, Banamber Sahoo, Subhada Prasad Pani, Mariam Otmani del Barrio, Sanghamitra Pati
Summary: The COVID-19 pandemic has different effects on men, women, and the transgender population. However, there is limited evidence on the impact of gender and other social determinants of health in resource-constrained urban settings during COVID-19. This review highlights the gender dimensions of health-related challenges among the urban poor in LMICs. The findings show that men experience more stress while women experience more anxiety, possibly due to their roles as caregivers and the impact of literacy and economy on vulnerability.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Psychology, Multidisciplinary
Susangita Jena, Jayashree Parida, Arpita Panda, Swati Sukalyani Behera, Abinash Pradhan, Prasanna Kumar Patra, Sanghamitra Pati, Harpreet Kaur, Subhendu Kumar Acharya
Summary: Unhealthy food behaviors are a major cause of the increasing burden of non-communicable diseases among Indian adolescents. Insufficient knowledge about healthy food choices and various influencing factors, such as peer influence, parental behavior, and mass media exposure, contribute to these behaviors. The scoping review highlights the need for targeted interventions to improve knowledge and practices related to healthy food choices among Indian adolescents and to increase awareness of the risks of non-communicable diseases.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Preety Sthutika Swain, Sunita Panda, Sanghamitra Pati, Budheswar Dehury
Summary: This study investigates the impact of TREM2 gene mutations on NHD and AD using 12 structure-based methods. The research findings highlight the significance of W50 and V126 in maintaining the structure of TREM2, and suggest a potential role for residue Y108 in TREM2's structure and function. Furthermore, the importance of R47 and R62 in the ligand binding region CDR loops is emphasized.
JOURNAL OF MOLECULAR MODELING
(2023)
Review
Health Care Sciences & Services
Manisha Mishra, Debasini Parida, Jogesh Murmu, Damini Singh, Tanveer Rehman, Jaya Singh Kshatri, Sanghamitra Pati
Summary: This study conducted a systematic review and meta-analysis to evaluate the effectiveness of mHealth interventions in monitoring antenatal care among pregnant women in low- and middle-income countries (LMICs). The findings indicate that antenatal mothers who used mobile health interventions were more likely to attend ANC check-ups. Policymakers should prioritize the integration of mHealth interventions into maternal healthcare services in LMICs.
Article
Public, Environmental & Occupational Health
Madhusmita Bal, Jyoti Ghosal, Arundhuti Das, Sonali Sandeepta, Sanghmitra Pati, Ambarish Dutta, Manoranjan Ranjit
Summary: The study aimed to estimate the prevalence of malaria infection in pregnant women in high malaria-endemic and hard-to-reach areas of Odisha, India, and its impact on birth weight. The results showed that half of the pregnant women in high-endemic areas had sub-patent malaria infection, which had a negative impact on the birth weight of their newborns. Therefore, the prevalence of sub-patent infection is considered a public health concern.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2023)
Article
Integrative & Complementary Medicine
Roja Varanasi, Abhinav Sinha, Debadatta Nayak, Raj K. Manchanda, Rajiv Janardhanan, Simran Tandon, Sanghamitra Pati
Summary: The prevalence of multimorbidity was high in AYUSH primary care settings in India, with diabetes being the most common chronic condition among patients. Participants aged 70 and above, females, and middle-class individuals showed a higher likelihood of having multimorbidity. The results suggest the need for targeted behavioral change communication for these specific groups.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2023)
Article
Rheumatology
Sibabratta Patnaik, Prakashini Mruthyunjaya, Krushna Chandra Murmu, Soumendu Mahapatra, A. Raj Kumar Patro, Ramnath Misra, Sanghamitra Pati, Punit Prasad, Sakir Ahmed
Summary: MIS-C, a rare highly inflammatory disease associated with COVID-19, shares similarities with incomplete Kawasaki disease. Through RNAseq analysis, researchers found differences in gene expression between MIS-C and healthy controls, Kawasaki disease, and systemic Juvenile Idiopathic Arthritis. NABA matrisome activation was significantly upregulated in MIS-C compared to healthy controls, while IL-10 pathways were downregulated. MIS-C showed more activation in neutrophil degranulation and acquired immune activation compared to Kawasaki disease, but less involvement in coagulation and heat-shock systems. Compared to systemic Juvenile Idiopathic Arthritis, MIS-C exhibited activation in humoral immune response and complements, as well as higher matrisome activation.
RHEUMATOLOGY INTERNATIONAL
(2023)