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Immunology
Yanmin He, Xiaozhen Hong, Jingjing Zhang, Ji He, Faming Zhu, He Huang
Summary: In this study, we established an NGS method for analyzing the sequence of the start codon to the stop codon in the ABO gene. Through analysis of 110 individuals, we identified two novel ABO alleles and confirmed the presence of DNA recombination in ABO alleles.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biochemical Research Methods
Matteo Chiara, Anna Maria D'Erchia, Carmela Gissi, Caterina Manzari, Antonio Parisi, Nicoletta Resta, Federico Zambelli, Ernesto Picardi, Giulio Pavesi, David S. Horner, Graziano Pesole
Summary: Various NGS-based strategies have been used to trace infectious agent origins and develop molecular diagnostic tests. The ongoing COVID-19 pandemic has caused severe societal and economic costs, emphasizing the importance of efficient sequencing methods. However, different technologies and approaches have their own advantages and limitations, highlighting the need for better integration and sharing of data.
BRIEFINGS IN BIOINFORMATICS
(2021)
Article
Multidisciplinary Sciences
Andrew E. Short, Dowan Kim, Prasaad T. Milner, Corey J. Wilson
Summary: This study presents a technology that uses repurposed parts of Transcriptional Programming to regulate recombinase function and facilitate synthetic memory in the living system. The interception synthetic memory allows programmable loss-of-function and gain-of-function, as well as nested Boolean logical operations. It offers a 5-fold increase in memory capacity compared to previous generations and is 10 times faster. This memory technology complements decision-making via Transcriptional Programming and can be used in developing intelligent synthetic biological systems.
NATURE COMMUNICATIONS
(2023)
Editorial Material
Cell Biology
Nanying Chen, Wei Zhang, Xianguo Xu, Ji He, Faming Zhu
Summary: HLA-DRB1*12:01:10 differs from HLA-DRB1*12:01:01:01 by a single nucleotide substitution in exon 4.
Article
Genetics & Heredity
Berkay Kirnaz, Yuksel Gezgin, Afig Berdeli
Summary: This study examined the genotype distributions of common MEFV variants in the Turkish population and evaluated all rare mutations using targeted NGS. The results revealed a wide range of mutations and genotypes, including two novel mutations. The findings contribute valuable data for future genotype-phenotype studies of Familial Mediterranean Fever.
Article
Multidisciplinary Sciences
Wonjae Chang, Jungsub Kim, Myoungsoo Kim, Min Woo Lee, Chung Hyun Lim, Gunho Kim, Sunghyun Hwang, Jeeyoung Chang, Young Hwan Min, Kiseong Jeon, Soohyun Kim, Yoon-Ho Choi, Jeong Soo Lee
Summary: MicroLED technology is being commercialized for large-screen displays and actively researched for other applications. However, there are obstacles in transfer technology that need to be overcome for microLEDs to enter mainstream markets. Researchers have developed a new transfer method using magnetic and dielectrophoresis forces, achieving a high transfer yield and demonstrating its potential for high-volume production.
Editorial Material
Cell Biology
Yizhen He, Lina Dong, Ying Li, Wei Zhang, Faming Zhu
Summary: HLA-C*08:232 differs from HLA-C*08:01:01:01 by a single nucleotide substitution at position 629 A > G.
Editorial Material
Cell Biology
Abdelhamid Liacini, Lindsey Peters, Shannon Mancini, Yuri Persidsky, Steven Geier
Summary: HLA-DPA1*01:144 differs from HLA-DPA*01:03:01:04 by a nucleotide substitution at position 44, which results in a change in codon-17 located in exon 1.
Editorial Material
Cell Biology
Heekang Choi, Jun Young Hong, Sunmi Jung, Jina Lee, Younhee Park
Summary: The HLA-DPA1*02:89 allele differs from the HLA-DPA1*02:02:02:01 allele by a single nucleotide at codon 224.
Editorial Material
Cell Biology
Gregory Gatouillat, Thierry Tabary, Marcelle Tonye-Libyh, Bach Nga Pham, Delphine Giusti
Summary: HLA-A*01:383 differs from HLA-A*01:01:01:01 by two nucleotide substitutions at positions 28 and 48 in exon 1.
Editorial Material
Cell Biology
Raffaella Azzarone, Maria Scimitarra, Daniela Fracassi, Simona Scacchi, Franco Papola
Summary: HLA-A*31:11:02 and A*31:01:02 differ by one nucleotide substitution at position 565 in exon 3.
Editorial Material
Cell Biology
Mirzokhid Rakhmanov, Martin Bernheiden, Murielle Verboom, Florian Emmerich
Summary: HLA-C*15:255 differs from HLA-C*15:02:01 by five nucleotide substitutions located in exons 4 and 5.
Editorial Material
Cell Biology
David Guillermo Hernandez, Nathalie Camacho Ramirez, Melissa Mosquera Martinez, Paola Andrea Cendales, Bernardo Armando Camacho
Summary: HLA-DRB1*04:315 differs from HLA-DRB1*04:07:01:02 by a single nucleotide substitution in codon 147 of exon 3.
Editorial Material
Cell Biology
Gregory Gatouillat, Marcelle Tonye-Libyh, Thierry Tabary, Bach Nga Pham, Delphine Giusti
Summary: HLA-C*07:1001N differs from HLA-C*07:01:01:01 by a deletion of 17 nucleotides in exon 1.
Editorial Material
Cell Biology
Abdelhamid Liacini, Lindsey Peters, Christopher Gravante, Kimberly Pfau, Steven Geier
Summary: A point mutation in Exon 1 causes a non-synonymous change to the start codon, potentially impacting expression.
Article
Biochemical Research Methods
Yingying Wei, Hao Wu
Article
Oncology
Xia Li, Hailiang Huang, Yanfang Guan, Yuhua Gong, Cheng-Yi He, Xin Yi, Ming Qi, Zhi-Ying Chen
Article
Oncology
Daria A. Gaykalova, Veronika Zizkova, Theresa Guo, Ilse Tiscareno, Yingying Wei, Rajita Vatapalli, Patrick T. Hennessey, Julie Ahn, Ludmila Danilova, Zubair Khan, Justin A. Bishop, J. Silvio Gutkind, Wayne M. Koch, William H. Westra, Elana J. Fertig, Michael F. Ochs, Joseph A. Califano
Article
Statistics & Probability
Xiangyu Luo, Yingying Wei
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
(2019)
Article
Statistics & Probability
Xiangyu Luo, Yingying Wei
ANNALS OF APPLIED STATISTICS
(2018)
Article
Biochemical Research Methods
Zhenwei Dai, Sunny H. Wong, Jun Yu, Yingying Wei
Article
Biology
Yan Wang, Haizhen Long, Juan Yu, Liping Dong, Michel Wassef, Baowen Zhuo, Xia Li, Jicheng Zhao, Min Wang, Cuifang Liu, Zengqi Wen, Luyuan Chang, Ping Chen, Qian-fei Wang, Xueqing Xu, Raphael Margueron, Guohong Li
Article
Biochemistry & Molecular Biology
Xia Li, Yunpeng Cai
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2018)
Article
Cell Biology
Xia Li, Yunpeng Cai
Article
Multidisciplinary Sciences
Xiangyu Luo, Can Yang, Yingying Wei
NATURE COMMUNICATIONS
(2019)
Article
Cell Biology
Xia Li, Yunpeng Cai
Editorial Material
Oncology
Xia Li, Dong-Hua Yang, Prathibha Ranganathan
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Xia Li, Yujie Yang, Jing Zheng, Ye Li, Denan Lin, Yunpeng Cai
ACTA MEDICA MEDITERRANEA
(2018)