Article
Agriculture, Dairy & Animal Science
G. Schiavo, S. Bovo, M. Munoz, A. Ribani, E. Alves, J. P. Araujo, R. Bozzi, M. Candek-Potokar, R. Charneca, A. Fernandez, M. Gallo, F. Garcia, D. Karolyi, G. Kusec, J. M. Martins, M-J Mercat, Y. Nunez, R. Quintanilla, C. Radovic, V Razmaite, J. Riquet, R. Savic, G. Usai, V. J. Utzeri, C. Zimmer, C. Ovilo, L. Fontanesi
Summary: ROHs are long stretches of DNA that indicate the level and origin of inbreeding, with frequent common ROHs defining ROH islands. Comparative analysis shows similar genetic structures among European local pig breeds, contributing to understanding their genetic history. The study helps manage genetic resources of the investigated pig breeds.
Article
Genetics & Heredity
Adeniyi C. Adeola, Semiu F. Bello, Abdussamad M. Abdussamad, Akanbi I. Mark, Oscar J. Sanke, Anyebe B. Onoja, Lotanna M. Nneji, Nasiru Abdullahi, Sunday C. Olaogun, Lawal D. Rogo, Godwin F. Mangbon, Shamsudeen L. Pedro, Manasseh P. Hiinan, Muhammad M. Mukhtar, Jebi Ibrahim, Hayatu Saidu, Philip M. Dawuda, Rukayya K. Bala, Hadiza L. Abdullahi, Adebowale E. Salako, Samia Kdidi, Mohamed Habib Yahyaoui, Ting-Ting Yin
Summary: This research is the first to investigate the polymorphism of scrapie-related genes in Nigerian goats.
Article
Agriculture, Dairy & Animal Science
Shinji Sasazaki, Koichiro Tomita, Yuto Nomura, Fuki Kawaguchi, Tetsuo Kunieda, Manoj Kumar Shah, Hideyuki Mannen
Summary: Multiple gene polymorphisms associated with high-altitude adaptation in goats were reported in this study, where the mutant allele frequencies tended to increase with breeding altitude increase, indicating a significant contribution to high-altitude adaptation in Nepalese goat breeds.
ANIMAL SCIENCE JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
Julie Colpitts, Philip Dunstan McLoughlin, Jocelyn Poissant
Summary: This study reveals that Sable Island horses are more inbred than domestic breeds, and most of this inbreeding is due to historical bottlenecks and founder effects rather than recent mating between close relatives. Unique ROH islands in the Sable Island population suggest adaptation to local selective pressures and/or strong genetic drift, highlighting the value of this population as a reservoir of equine genetic variation.
Article
Genetics & Heredity
Ann Ying-An Chen, Chao-Wei Huang, Shyh-Hwa Liu, An-Chi Liu, Hso-Chi Chaung
Summary: This study investigated the distribution of SNP sites in immune-related genes and their correlations with cell surface markers in different breeds of pigs. The findings revealed significant SNP differences among breeds, particularly between Taiwan black and Landrace pigs, as well as correlations between certain SNPs and the expression of cell surface markers. Understanding the genetic uniqueness of each breed could help identify functionally important SNPs in immunoregulation.
Article
Cell Biology
Michal Pac, Natalia Krata, Barbara Moszczuk, Aleksandra Wyczalkowska-Tomasik, Beata Kaleta, Bartosz Foroncewicz, Witold Rudnicki, Leszek Paczek, Krzysztof Mucha
Summary: Glomerular diseases such as IgA nephropathy and membranous nephropathy are influenced by NR3C1 gene polymorphisms, which can affect treatment susceptibility and clinical outcomes. Specific associations were found between certain SNPs and these diseases, as well as response to steroid therapy.
Article
Agriculture, Dairy & Animal Science
Asma Arjoune, Abrar B. B. Alsaleh, Safia A. A. Messaoudi, Hanen Chelbi, Refka Jelassi, Mourad Assidi, Taha Najar, Brahim Haddad, Marc-Andre Sirard
Summary: The aim of this research was to study the effect of MTNR1A gene polymorphisms on the reproductive performance of two Mediterranean sheep breeds. A total of 26 SNPs were found, and three SNPs caused amino acid changes. Two SNPs were totally linked and correlated with reproductive activity resumption. This study provides new knowledge for the control of sheep reproductive seasonality and farm management.
Article
Biotechnology & Applied Microbiology
Dennis N. Lozada, Madhav Bhatta, Danise Coon, Paul W. Bosland
Summary: Genetic diversity among New Mexican chile peppers was assessed using GBS-derived SNP markers, revealing genetic relatedness among different populations. Introducing novel alleles from other breeding programs or wild species could help increase diversity in the current germplasm. Valuable information for future association mapping and genomic selection for genetic improvement through marker-assisted breeding in New Mexican chile peppers was presented.
Article
Agriculture, Dairy & Animal Science
L. Pulinas, J. Staric, G. Cosso, G. Curone, M. C. Mura, V. Carcangiu, S. Luridiana
Summary: The aim of this study was to investigate the effect of MTNR1A gene polymorphisms on reproductive performance in dairy sheep breeds of different latitudes, and to compare the effects of different season of male placement with females in breeding systems in Italy and Slovenia. The results showed that the nucleotide sequences of the MTNR1A gene could affect reproductive functions of Mediterranean sheep.
ANIMAL REPRODUCTION SCIENCE
(2022)
Article
Veterinary Sciences
Ahmed I. Ateya, Samer S. Ibrahim, Mona M. Al-Sharif
Summary: This study investigated the single nucleotide polymorphisms, gene expression, and economic evaluation of mastitis susceptibility in Holstein and Brown Swiss dairy cows. The results showed that certain genes may play a significant role in mastitis tolerance/susceptibility, and mastitis has detrimental impacts on the economic efficiency of dairy farms.
VETERINARY SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Evanthia Thanou, Daniel Jablonski, Panagiotis Kornilios
Summary: Within the Balkan Peninsula, topographic and climatic factors have played a significant role in shaping the biodiversity and speciation history of ectotherms like the nose-horned viper species-complex. The study reveals that cycles of isolation and expansion during glacial-interglacial periods have led to allopatric speciation and the formation of hybrid zones in different parts of the Balkan Peninsula. Furthermore, the study proposes an evolutionary scenario that resolves conflicts between genomic and mitochondrial phylogenies.
Article
Agriculture, Dairy & Animal Science
Jiajin Huang, Xiang Chen, Lingang Dai, Jiali Xu, Meimei Xiao, Yong Ruan
Summary: This study explored the correlation between SNP of the PLIN2 gene and lambing performance in Qianbei Ma goats. The results showed that PLIN2 protein in Qianbei Ma goats had a close genetic relationship with sheep and a distant relationship with mice. Several SNPs related to lambing traits were identified, and these SNPs had significant genetic effects on the lambing performance of Qianbei Ma goats.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Article
Biodiversity Conservation
Melanie E. F. LaCava, Roderick B. Gagne, Kyle D. Gustafson, Sara Oyler-McCance, Kevin L. Monteith, Hall Sawyer, Matthew J. Kauffman, Daniel J. Thiele, Holly B. Ernest
Summary: Maintaining functional connectivity is crucial for wildlife conservation. Landscape genomics helps to assess long-term functional connectivity by relating environmental variables to spatial patterns of genomic variation. This study on mule deer genetic structure and diversity using landscape genomics highlights the impact of different environmental variables on gene flow, revealing scale-dependent connectivity patterns.
Article
Agriculture, Dairy & Animal Science
Cuiling Wua, Chongkai Qin, Xuefeng Fu, Bingru Zhao, Yujiang Wu, Junmin He, Jingyi Mao, Jing Liu, Xixia Huang, Kechuan Tian
Summary: This study identified the polymorphisms of KRTAP genes in Jiangnan and Tibetan cashmere goats and found their correlation with fiber diameter. A total of 28 mutation sites were identified, providing valuable information for improving fiber diameter and preserving germplasm resources of cashmere goats.
CANADIAN JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Cuiling Wua, Chongkai Qin, Xuefeng Fu, Bingru Zhao, Yujiang Wu, Junmin He, Jingyi Mao, Jing Liu, Xixia Huang, Kechuan Tian
Summary: In this study, the exon regional polymorphisms of KRTAP genes in Jiangnan and Tibetan cashmere goats were identified, and their effects on fiber diameter were analyzed. The results showed that the polymorphisms of KRTAP13.1, KRTAP27-1, and KRTAP24-1 genes were significantly related to the fiber diameter of Jiangnan cashmere goats.
CANADIAN JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Food Science & Technology
Sofia Duarte-Coimbra, Giovanni Forcina, Lucia Perez-Pardal, Albano Beja-Pereira
Summary: Recent studies suggest that microorganisms, especially bacteria, on the dorsum of the tongue have the potential to influence flavor perception, making it crucial to understand the association between tongue dorsum biofilm and taste for a better understanding of the role played by these bacteria in wine tasting. In this study, the microbiomes of 58 samples from professional wine tasters and 30 samples from non-professional wine tasters were analyzed. The results showed significant differences in bacterial diversity between the two groups, and the presence of new bacterial taxa after wine tasting, particularly in frequent wine tasters of sparkling wines.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Zoology
Hojjat Asadollahpour Nanaei, Yudong Cai, Akil Alshawi, Jiayue Wen, Tanveer Hussain, Wei-Wei Fu, Nai-Yi Xu, Abdulameer Essa, Johannes A. Lenstra, Xihong Wang, Yu Jiang
Summary: Understanding the genetic background and history of goat populations in Southwest Asia, this study analyzed whole-genome sequencing data from native goat populations in Iraq and Pakistan, combined with data from modern, ancient, and wild Capra species worldwide. The results showed that gene flow from the eastern Mediterranean during the Chalcolithic period deeply influenced the genetic structure of Southwest Asian goats, reflecting adaptation to gradual warming and aridity in the region. Additionally, the study revealed adaptive introgression of a genetic locus from the Nubian ibex into African and Southwest Asian goats.
ZOOLOGICAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Pierluigi Reveglia, Carmela Paolillo, Antonella Angiolillo, Gabriella Ferretti, Ruggero Angelico, Rossana Sirabella, Gaetano Corso, Carmela Matrone, Alfonso Di Costanzo
Summary: Alzheimer's disease is the most common cause of dementia in the elderly population. It not only affects the brain, but also disturbs the overall metabolism of the body. Analysis of blood samples from patients with AD revealed significant dysregulation of metabolites, including upregulation of glycerophospholipids and ceramide, and downregulation of glutamic acid, other phospholipids, and sphingolipids. Pathway analysis showed that at least five metabolic pathways related to polar compounds were dysregulated in AD patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Anila Hoda, Xhiliola Bixheku, Mirela Lika (Cekani)
Summary: This study investigates the potentially deleterious nsSNPs in the PKLR gene for milk production traits in cows using computational tools. In silico analysis reveals that out of 170 nsSNPs, only 18 are considered deleterious. Protein stability analysis confirms that 9 nsSNPs decrease protein stability. ConSurf analysis predicts that all 18 nsSNPs are evolutionarily conserved. Two different domains of PKLR protein are identified, with 12 nsSNPs in the Pyruvate Kinase barrel domain and 6 nsSNPs in the Pyruvate Kinase C Terminal. Molecular dynamics simulations confirm the impact of nsSNPs on protein structure and function. This study provides valuable information about functional SNPs that affect PKLR protein in cattle.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Multidisciplinary Sciences
N. Pirhadi, M. Parrondo, A. Romero-Bascones, R. Thoppil, J. L. Martinez, M. P. Fernandez-Rueda, I. Marquez, L. Garcia-Florez, E. Dopico, T. Perez, Y. J. Borrell
Summary: The octopus species O. vulgaris has great economic value and is fished in the western Asturias region of Spain. However, there has been no genetic assessment of the octopus stocks in this area. This study collected and genotyped 539 individuals from different regions to assess the genetic differentiation. The results showed at least four genetically different stocks and stable genetic variation in Asturias, indicating sustainable fishery levels.
SCIENTIFIC REPORTS
(2023)
Article
Genetics & Heredity
Hong Cheng, Zhuangbiao Zhang, Jiayue Wen, Johannes A. Lenstra, Rasmus Heller, Yudong Cai, Yingwei Guo, Ming Li, Ran Li, Wenrong Li, Sangang He, Jintao Wang, Junjie Shao, Yuxuan Song, Lei Zhang, Masum Billah, Xihong Wang, Mingjun Liu, Yu Jiang
Summary: This study analyzed the whole-genome sequencing of 1,098 domestic sheep and 69 wild sheep, and found that introgression from wild sheep contributed to the morphological diversity of sheep breeds and individual variations within breeds. The frequency of introgressed fragments varied greatly among domestic breeds, indicating the role of selection and recombination in shaping genetic and phenotypic diversity.
Article
Agriculture, Dairy & Animal Science
Matteo Cortellari, Arianna Bionda, Raffaella Cocco, Sara Sechi, Luigi Liotta, Paola Crepaldi
Summary: This study analyzed the genomic background of the Fonni's dog and found that it is closely related to other shepherd dogs while also having unique genetic characteristics. The study compared different phenotypical and genetic scores and found a positive correlation, with the genomic score having the highest correlation with breed typicality. The judges' score showed little variability and could be improved to better evaluate the breed. The recovery and preservation of the Fonni's dog will require collaboration between breeders and the Italian kennel club, as well as support from regional programs.
Article
Multidisciplinary Sciences
A. Angiolillo, D. Leccese, S. Ciccotelli, G. Di Cesare, K. D'Elia, N. Aurisano, C. Matrone, C. Dentizzi, A. Di Costanzo
Summary: Non-pharmacological approaches, such as exercise programs like Nordic Walking (NW), have shown potential in improving cognitive function and behavioral symptoms in patients with Alzheimer's disease (AD). A pilot study with 30 AD patients demonstrated that NW can significantly improve cognitive domains like visual-spatial abilities and verbal episodic memory, suggesting it as a safe and potentially useful strategy in slowing down cognitive impairment in mild/moderate AD.
Article
Agriculture, Dairy & Animal Science
Salvatore Bordonaro, Giorgio Chessari, Salvatore Mastrangelo, Gabriele Senczuk, Stefania Chessa, Bianca Castiglioni, Serena Tumino, Donata Marletta, Andrea Criscione
Summary: Comparison of the genomic data of Nero Siciliano pig breed with wild boar, Italian local, and cosmopolitan breeds revealed its genetic similarity to wild boar and the presence of internal substructure. The breed showed a low level of hybridization, high genetic diversity index, and genomic regions associated with productive QTL. These findings contribute to a better understanding of the genomic profile of the local breed for mating plans, maintaining internal diversity, and optimizing the production system.
Article
Ecology
Stephane Blondeau Da Silva, Joram M. Mwacharo, Menghua Li, Abulgasim Ahbara, Farai Catherine Muchadeyi, Edgar Farai Dzomba, Johannes A. Lenstra, Anne Da Silva
Summary: This study investigated how shared IBD patterns between individuals of the same breed can indicate the level of admixture. The findings showed that breeds with higher genetic isolation had more shared and longer IBD segments. This study paves the way for further research on the development of admixture indicators based on intra-breed shared IBD segments.
Article
Agriculture, Dairy & Animal Science
Katherine D. Arias, Hanboreum Lee, Riccardo Bozzi, Isabel Alvarez, Juan Pablo Gutierrez, Ivan Fernandez, Juan Menendez, Albano Beja-Pereira, Felix Goyache
Summary: In this study, genomic regions that might contain signatures of selection peculiar to the Celtic-Iberian pig strain were identified. A total of 39 candidate regions and 7 candidate genes were determined, potentially associated with the characteristics and adaptability of the Celtic-Iberian pig strain.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2023)
Article
Agriculture, Dairy & Animal Science
Trinidad Perez, Andrea Romero-Bascones, Negin Pirhadi, Ruth Coya, Maria del Pino Fernandez-Rueda, Isabel Marquez, Lucia Garcia-Florez, Yaisel J. Borrell
Summary: The artisanal octopus fishery is a traditional industry in Northern Spain that has a significant economic impact. This study investigates the genetic patterns of octopus populations using mitochondrial DNA analysis. The results reveal two main lineages with distinct distributions, and temporal changes in their distribution are linked to oceanographic conditions. These findings provide valuable information for understanding the uniqueness of the exploited population and the impact of exploitation on its long-term survival.
Article
Agriculture, Dairy & Animal Science
Serena Tumino, Matteo Bognanno, Giorgio Chessari, Marco Tolone, Salvatore Bordonaro, Fabrizio Mangano, Donata Marletta, Marcella Avondo
Summary: This study examined the impact of genotypes and feed integration on milk quality in Valle del Belice sheep, and found that the DGAT1 genotype significantly affected milk urea content and fatty acid composition. Carob pulp supplementation increased milk fat content but worsened the milk fatty acid profile in terms of healthy properties.
Article
Agriculture, Dairy & Animal Science
Arianna Bionda, Vincenzo Lopreiato, Annalisa Amato, Matteo Cortellari, Carmelo Cavallo, Vincenzo Chiofalo, Paola Crepaldi, Luigi Liotta
Summary: This study aims to advance the recognition process of the Comune di Sicilia goat as a distinct breed by characterizing its phenotypic and genomic features. The research identifies distinctive genomic and phenotypic traits in the Comune di Sicilia breed, distinguishing it from other breeds in the same region. A comprehensive approach considering both morphology and genomic background is recommended to ensure the preservation of the breed and prevent excessive inbreeding.
Article
Agriculture, Dairy & Animal Science
Esterina Fazio, Arianna Bionda, Vincenzo Chiofalo, Deborah La Fauci, Cinzia Randazzo, Alessandra Pino, Paola Crepaldi, George Attard, Luigi Liotta, Vincenzo Lopreiato
Summary: Further research on the relationship between endocrine adaptation, body weight, and productive performances is of great interest. The use of olive cake in animal feed formulations has positive effects on the quality of final products and does not have a detrimental effect on maintaining physiological hormone concentrations. Incorporating agro-industrial by-products into livestock feed formulations can also positively impact feed costs and promote a circular bio-economy.