Article
Cell Biology
Roberta Di Fonte, Sabino Strippoli, Marianna Garofoli, Gennaro Cormio, Simona Serrati, Vera Loizzi, Rossella Fasano, Francesca Arezzo, Mariateresa Volpicella, Afshin Derakhshani, Michele Guida, Letizia Porcelli, Amalia Azzariti
Summary: This study found that cervical and ovarian cancer cells are responsive to trabectedin and that the combination with propranolol enhances its efficacy. These findings provide new possibilities for the treatment of cervical cancer.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Health Care Sciences & Services
Lucia Volpato, Maria del Rio Carral, Nicolas Senn, Marie Santiago Delefosse
Summary: General practitioners perceive wearable devices as user-friendly tools that can support patient empowerment, behavior change, and improve awareness of medical history and body functionality. However, concerns remain regarding lack of scientific validation, issues with data protection, and potential stakeholder-associated financial interests. The study emphasizes the importance of involving medical professionals in the development and design of wearables to address these concerns.
JMIR MHEALTH AND UHEALTH
(2021)
Article
Health Care Sciences & Services
Charlotte Blease, John Torous, Zhiyong Dong, Gail Davidge, Catherine DesRoches, Anna Kharko, Andrew Turner, Ray Jones, Maria Hagglund, Brian McMillan
Summary: This study explores the experiences and opinions of GPs in England regarding patient access to their web-based health records. The majority of GPs expressed skepticism about the benefits of access for both patients and their practices.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Primary Health Care
Maria Bundgaard, Dorte Ejg Jarbol, Jens Sondergaard, Marius Brostrom Kousgaard, Sonja Wehberg, Line Bjornskov Pedersen
Summary: Quality clusters, introduced in Danish general practice, anchor quality improvement in local clusters managed by general practitioners. The study findings suggest that frequent and active meetings with relevant content are positively related to GPs' perceived benefits and improved collaboration.
Article
Psychiatry
Ira R. Katz, Sandra Resnick, Rani Hoff
Summary: Findings from the Veterans Outcome Assessment (VOA) survey show that better communication and quality of mental health care predict more favorable outcomes for Veterans in VHA general mental health clinics. Further research is needed to determine if including these factors in measurement-based care could improve outcomes by identifying care problems early.
PSYCHIATRY RESEARCH
(2021)
Article
Immunology
Francesco Napolitano, Concetta Paola Pelullo, Giorgia Della Polla, Italo Francesco Angelillo
Summary: The survey showed that the majority of general practitioners in Italy consider the HPV vaccine to be safe and effective, with those receiving information from scientific journals more likely to have a positive attitude towards its effectiveness. The willingness and behavior of recommending the HPV vaccine may be influenced by the physician's perception of its efficacy and safety.
Article
Dentistry, Oral Surgery & Medicine
C. C. Currie, J. Palmer, S. J. Stone, P. Brocklehurst, V. R. Aggarwal, P. J. Dorman, M. S. Pearce, J. Durham
Summary: This study investigated the attendance trends of patients with persistent orofacial pain (POFP) in Welsh medical practices. The attendance rate increased over the 44-year period, and a significant number of patients had multiple attendances. Referral rates were higher in females, rural residents, and those in the least deprived quintile.
JOURNAL OF DENTAL RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Angela Salomon, Jody Boffa, Sizulu Moyo, Jeremiah Chikovore, Giorgia Sulis, Benjamin Daniels, Ada Kwan, Tsatsawani Mkhombo, Sarah Wu, Madhukar Pai, Amrita Daftary
Summary: There are concerns about inappropriate antimicrobial use, private healthcare costs, and TB diagnostic delay in the prescribing practices among private general practitioners for individuals with TB-like symptoms in South Africa.
Article
Public, Environmental & Occupational Health
Malgorzata Znyk, Dorota Kaleta
Summary: This study aimed to determine the influence of personal factors, such as body mass index (BMI), of general practitioners (GPs) on their counseling behaviors and patient health management. The study found that only a small percentage of physicians always provided advice on diet and physical activity, and most GPs only occasionally provided counseling. GPs who engaged in physical activity and measured patient weight, height, and BMI were more likely to provide advice on nutrition and physical activity. Lack of time was identified as the main barrier to counseling.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Hospitality, Leisure, Sport & Tourism
Alessandro Quartiroli, Justine Vosloo, Shelby N. Anderson, Jaclyn Ditter, Meghan Keeley
Summary: This study explores the migratory experiences of sport psychology practitioners, including motivations, challenges, and benefits. Participants highlighted the positive impact of their transnational experience on their personal and professional lives, while also addressing personal and professional difficulties. Recommendations were made for professional organizations to address systematic barriers and enhance practitioners' transnational experiences.
PSYCHOLOGY OF SPORT AND EXERCISE
(2021)
Article
Multidisciplinary Sciences
Adriaan Barbaroux, Isabelle Pourrat, Tiphanie Bouchez
Summary: French general practitioners have an unfavorable opinion of the pharmaceutical industry, but their behavior towards sales representatives is generally positive. This study explores the reasons behind this discrepancy and reveals practical, social, and psychological motivations that lead GPs to continue meeting with sales reps.
Article
Medical Informatics
Masaharu Nakayama, Ryusuke Inoue, Satoshi Miyata, Hiroaki Shimizu
Summary: The study investigated the impact of promoting collaboration between specialists and GPs through HIE, and found that in rural areas, this collaboration may improve clinical outcomes for low-to-moderate risk patients. While there were no significant differences in all-cause mortality and serious adverse events between the groups in intention-to-treat analysis, per-protocol analysis showed significantly reduced all-cause mortality and serious adverse event incidence in the intervention group compared to the control group.
APPLIED CLINICAL INFORMATICS
(2021)
Article
Multidisciplinary Sciences
Jannik M. Tielker, Jan P. Weber, Steffen T. Simon, Claudia Bausewein, Stephanie Stiel, Nils Schneider
Summary: The study investigated the experiences, challenges, and perspectives of German GPs regarding end-of-life care during the first peak of the pandemic in spring 2020. Results showed that while most GPs believed that the quality of end-of-life care for patients was maintained during the pandemic, a significant proportion reported a decrease in quality. Changes in contact methods with patients, such as increased telephone contact and video consultations, were observed during the pandemic.
Article
Education & Educational Research
Adam McBride, Claire Collins, Brian Osborne, Helen McVeigh
Summary: This article discusses the regulation of mandatory continuing professional development for doctors by the Irish Medical Council and explores the impact of CPD on patient care. A survey conducted among general practitioners found that the majority considered CPD to be beneficial to patient care. However, there were differences in responses to different types of CPD activities among different demographic groups.
BMC MEDICAL EDUCATION
(2022)
Article
Economics
Cristina Belles-Obrero, Emma Duchini
Summary: This paper examines the impact of an educational reform introduced in 1990 on educational pathways and employment outcomes. The results suggest that shifting educational investment from vocational to general education after age 16 can improve occupational outcomes and wages, but these positive effects are mainly concentrated among middle to high-skilled individuals, while individuals who only receive basic general education have worse long-term employment prospects than vocationally-trained individuals.
ECONOMICS OF EDUCATION REVIEW
(2021)
Article
Social Sciences, Interdisciplinary
Hans Thulesius, Ulrika Sanden, Davorina Petek, Robert Hoffman, Tuomas Koskela, Bernardino Oliva-Fanlo, Ana Luisa Neves, Senada Hajdarevic, Lars Harrysson, Berit Skjodeborg Toftegaard, Peter Vedsted, Michael Harris
Summary: Through analyzing the survey responses, interviews, and literature, it is found that the timeliness of cancer diagnosis in primary care can be improved by implementing strategies such as pluralistic task shifting, cognitive task shifting, digital task shifting, and financial task shifting.
GROUNDED THEORY REVIEW
(2023)
Article
Medicine, General & Internal
Anette Fischer Pedersen, Peter Vedsted
Summary: Work pressure remains an issue among general practitioners, but they rarely seek help for symptoms of burnout. This study found that coping strategies used during time pressure were associated with burnout risk, and seeking help was linked to lower burnout risk.
Article
Oncology
Line Flytkjaer Virgilsen, Peter Vedsted, Alina Zalounina Falborg, Anette Fischer Pedersen, Anders Prior, Henry Jensen
Summary: Patients with pre-existing psychiatric disorders are less likely to be diagnosed through cancer patient pathways from primary care, especially for cancers that often present with vague or unspecific symptoms and among patients with severe psychiatric disorders.
Article
Oncology
Usha Menon, David Weller, Alina Zalounina Falborg, Henry Jensen, John Butler, Andriana Barisic, Anne Kari Knudsen, Rebecca J. Bergin, David H. Brewster, Victoria Cairnduff, Evangelia Ourania Fourkala, Anna T. Gavin, Eva Grunfeld, Elizabeth Harland, Jatinderpal Kalsi, Rebecca-Jane Law, Yulan Lin, Donna Turner, Richard D. Neal, Victoria White, Samantha Harrison, Irene Reguilon, Charlotte Lynch, Peter Vedsted
Summary: The international comparison study on ovarian cancer diagnosis routes and intervals reveals variations among different jurisdictions. This study presents an opportunity to improve the key intervals in diagnosis and treatment of ovarian cancer.
BRITISH JOURNAL OF CANCER
(2022)
Article
Health Care Sciences & Services
Linda A. Rasmussen, Line F. Virgilsen, Claus W. Fristrup, Peter Vedsted, Henry Jensen
Summary: Based on healthcare data in Denmark, this study found that patients with pancreatic cancer had increased healthcare contacts and diagnostic tests, particularly blood glucose testing, before the diagnosis. This pattern may represent an opportunity for earlier diagnosis of pancreatic cancer.
SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE
(2022)
Article
Health Care Sciences & Services
Cathrine Bell, Charlotte Weiling Appel, Anne Frolich, Anders Prior, Peter Vedsted
Summary: This study explored the feasibility of an intervention targeting patients attending multiple hospital outpatient clinics. The intervention aimed to coordinate outpatient appointments through enhanced collaboration across medical specialties. Results showed that in the first year, 20% of eligible patients were enrolled, with appointments aligned in 15% of patients. Overall, intervention components were delivered as intended and seemed acceptable.
INTERNATIONAL JOURNAL OF INTEGRATED CARE
(2022)
Article
Public, Environmental & Occupational Health
Cathrine Bell, Anders Prior, Anne Frolich, Charlotte Weiling Appel, Peter Vedsted
Summary: Multimorbidity is a global health challenge that affects the healthcare of adult Danish population. A study found that the majority of individuals with multimorbidity attended outpatient clinics in 2018, and a portion of them had multiple outpatient trajectories. A small proportion of patients placed significant demands on outpatient clinics due to frequent attendance, suggesting the need for a more uniform way of organizing outpatient trajectories for these patients.
CLINICAL EPIDEMIOLOGY
(2022)
Article
Oncology
Astrid Boennelykke, Henry Jensen, Lene Sofie Granfeldt Ostgard, Alina Zalounina Falborg, Anette Tarp Hansen, Kaj Sparle Christensen, Peter Vedsted
Summary: The study shows that persons with new-onset anaemia detected in general practice have a high risk of cancer, with a significantly higher risk for 'combined inflammatory iron deficiency anaemia' and 'anaemia of inflammation'. Increased awareness and action are needed for anaemia as a sign of cancer, and there is a call for research to improve initial pathway for new-onset anaemia in general practice.
Article
Oncology
B. Danckert, N. L. Christensen, A. Z. Falborg, H. Frederiksen, G. Lyratzopoulos, S. McPhail, A. F. Pedersen, J. Ryg, L. A. Thomsen, P. Vedsted, H. Jensen
Summary: This study found that there are variations in the routes to cancer diagnosis for different age groups. Middle-aged patients are more likely to be diagnosed through referral from primary care, while older patients are more likely to be diagnosed through unplanned admissions, death certificate only, and outpatient admissions.
Article
Oncology
Linda Aagaard Rasmussen, Henry Jensen, Anette Fischer Pedersen, Peter Vedsted
Summary: This study investigated the characteristics of cancer survivors with high levels of fear of cancer recurrence and how it is associated with their needs for care. The findings showed that fear of cancer recurrence was associated with female sex, younger age, comorbidity, advanced tumour stage, and discontent with cancer follow-up.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Line Flytkjaer Virgilsen, Alina Zalounina Falborg, Peter Vedsted, Anders Prior, Anette Fischer Pedersen, Henry Jensen
Summary: Unplanned presentation of cancer is more frequent in patients with psychiatric disorders compared to those without. Understanding the risk factors for unplanned presentation can aid in targeting interventions for early cancer diagnosis in patients with psychiatric disorders.
CANCER EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Jens Lind Gleerup, Peter Vedsted
Summary: This study assessed and compared the time intervals from first contact to diagnosis and treatment for patients with active tuberculosis in the cities and settlements of Greenland. The results showed that patients in settlements had longer waiting times and significantly longer diagnostic, system, and total intervals compared to patients in cities.
INTERNATIONAL JOURNAL OF CIRCUMPOLAR HEALTH
(2022)
Article
Health Care Sciences & Services
Nanna Holt Jessen, Henry Jensen, Alina Zalounina Falborg, Henning Glerup, Henning Gronbaek, Peter Vedsted
Summary: This study compared the number of contacts to general practice across 11 types of abdominal cancer in the year preceding diagnosis, revealing that patients with liver, pancreatic, kidney, and bladder cancers had higher and more prolonged use of general practice. This may suggest missed opportunities for cancer diagnosis.
SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE
(2022)
Article
Public, Environmental & Occupational Health
Helena Breum Pedersen, Bastian Breum Pedersen, Mark Biilmann, Malik Moller, Nicolai Lohse, Peter Vedsted, Soren Mikkelsen
Summary: This study provides an overview of medical evacuations in Greenland in 2018, including incidence, costs, and diagnoses. The findings show that medical evacuations in Greenland can be costly, with variations between different health regions. Pregnancy and childbirth are the main reasons for women's evacuations, while circulatory system and digestive tract diseases are the main reasons for men's evacuations. Combining evacuations of multiple patients can reduce the costs of medical evacuations.
INTERNATIONAL JOURNAL OF CIRCUMPOLAR HEALTH
(2022)
Article
Primary Health Care
Anders Prior, Claus Hostrup Vestergaard, Anette Riisgaard Ribe, Annelli Sandbaek, Flemming Bro, Peter Vedsted, Susan Smith, Mogens Vestergaard, Morten Fenger-Gron
Summary: This study aimed to investigate the frequency of chronic care services provided by GPs in Denmark and found that the variation in service provision across practices exceeded expected levels, suggesting the presence of inverse care law mechanisms.
BRITISH JOURNAL OF GENERAL PRACTICE
(2022)