Article
Biochemistry & Molecular Biology
Colin J. Shew, Paulina Carmona-Mora, Daniela C. Soto, Mira Mastoras, Elizabeth Roberts, Joseph Rosas, Dhriti Jagannathan, Gulhan Kaya, Henriette O'Geen, Megan Y. Dennis
Summary: Evidence shows that in humans, paralogous segmental duplication genes exhibit different expression patterns, possibly due to relaxed selection or neofunctionalization. While ancestral paralogs show greater expression conservation with chimpanzee orthologs, certain derived paralogs may retain or supplant ancestral functions.
MOLECULAR BIOLOGY AND EVOLUTION
(2021)
Article
Multidisciplinary Sciences
PingHsun Hsieh, Vy Dang, Mitchell R. Vollger, Yafei Mao, Tzu-Hsueh Huang, Philip C. Dishuck, Carl Baker, Stuart Cantsilieris, Alexandra P. Lewis, Katherine M. Munson, Melanie Sorensen, AnneMarie E. Welch, Jason G. Underwood, Evan E. Eichler
Summary: The study reveals that TRP channel-associated factor 1/2 (TCAF1/TCAF2) proteins antagonistically regulate the cold-sensor protein TRPM8 in human tissues and have undergone duplications and diversification in the process of evolution. Differential TCAF2 expression among human haplogroups and high levels of TCAF2 and TRPM8 expression in the liver and prostate of modern humans are observed.
NATURE COMMUNICATIONS
(2021)
Article
Genetics & Heredity
Xiao-Tong Li, Xing-Yu Feng, Zhen Zeng, Yang Liu, Zhu-Qing Shao
Summary: This study identified 31 HSF genes in Secale cereale, indicating it as a valuable resource for mining functional HSFs with a larger number of HSF genes than barley and wheat subgenomes. Analysis showed uneven distribution of HSF genes among S. cereale chromosomes, with no gene on chromosome 4. Phylogenetic analysis revealed more gene duplications in S. cereale than barley and wheat, while expression analysis showed diverse patterns across developmental stages and stress treatments, hinting at functional diversity within the gene family.
FRONTIERS IN GENETICS
(2021)
Article
Multidisciplinary Sciences
Magdalena Bohutinska, Jakub Vlcek, Sivan Yair, Benjamin Laenen, Veronika Konecna, Marco Fracassetti, Tanja Slotte, Filip Kolar
Summary: Parallel adaptation provides insight into evolutionary predictability through replicated natural experiments, showing varying levels of genomic parallelism depending on the genetic divergence between lineages. Studies on Arabidopsis species adapting to alpine environments identified 151 genes under positive selection associated with alpine colonization and response to environmental challenges. The extent of genomic parallelism decreases significantly with increasing genetic divergence, driven by the decreasing probability of repeated selection on the same alleles, highlighting the importance of genetic divergence in genome evolution predictability.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Huiqi Zhao, Hong Liao, Shuixian Li, Rui Zhang, Jing Dai, Pengrui Ma, Tianpeng Wang, Meimei Wang, Yi Yuan, Xuehao Fu, Jie Cheng, Xiaoshan Duan, Yanru Xie, Peng Zhang, Hongzhi Kong, Hongyan Shan
Summary: By conducting extensive studies, including phylogenetic analysis, comparative transcriptomics, and functional studies, the evolutionary histories, expression patterns, and functions of floral organ identity and symmetry genes in Delphinieae were clarified. It was found that the duplication and diversification of APETALA3-3 (AP3-3), AGAMOUS-LIKE6 (AGL6), CYCLOIDEA (CYC), and DIVARICATA (DIV) lineage genes were closely associated with the origin of Delphinieae flowers. Therefore, the duplication and diversification of floral symmetry genes, as well as their integration into the preexisting floral regulatory network, played a key role in the development of Delphinieae flowers.
Review
Genetics & Heredity
Elena Kuzmin, John S. Taylor, Charles Boone
Summary: Gene duplication is common across species, and the retention of duplicated genes may involve mechanisms such as functional redundancy, divergence, neofunctionalization, subfunctionalization, back-up compensation, and dosage amplification. Additionally, duplication may also be retained due to structural and functional entanglement. Advances in human gene editing have provided new tools to study the contributions of these factors to duplicate gene retention and genome evolution.
TRENDS IN GENETICS
(2022)
Article
Biochemistry & Molecular Biology
Giacinto De Vivo, Fabio Crocetta, Miriam Ferretti, Roberto Feuda, Salvatore D'Aniello
Summary: By investigating 74 lophotrochozoan genomes, we discovered that the common ancestor of Lophotrochozoa possessed at least seven paralog groups of opsins, with divergent evolutionary histories in different phyla. Moreover, we identified opsin-related pseudopsins in Bilateria for the first time, potentially crucial in unraveling opsin evolution.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Biochemistry & Molecular Biology
Maud Facon, Gwenaelle Deniot, Maryse Lode-Taburel, Heloise Archambeau, Emilie Montes, Younes Dellero, Loeiz Maillet, Anne-Marie Chevre, Mathieu Rousseau-Gueutin
Summary: Gene duplication plays a crucial role in plant evolution, adaptation, and diversification. This study investigates the retention and functional compensation of ancestral duplicated genes in the oilseed crop Brassica napus, using the example of the petC gene. The findings reveal that petC paleologs have retained their ancestral function and are compensatory in optimal environmental conditions.
PLANT MOLECULAR BIOLOGY
(2023)
Review
Genetics & Heredity
Jianbin Wang
Summary: Established genomic resources for Ascaris and its relatives have provided insights into programmed DNA elimination, small RNA networks, and the evolution of nematode sex chromosomes, highlighting potential drug targets for controlling parasitic nematodes.
Article
Plant Sciences
Shuang Wu, Jinyuan Chen, Ying Li, Ai Liu, Ao Li, Mou Yin, Nawal Shrestha, Jianquan Liu, Guangpeng Ren
Summary: Extensive genomic rearrangements and abundant repetitive elements were detected in plastomes of Medicago and its relatives. The repeat content was found to be positively correlated with the degree of genomic rearrangements, with repeat-mediated illegitimate recombination identified as the major mechanism leading to genome instability. The findings provide valuable genomic resources for further investigation into plastome evolution in legumes.
Article
Biochemistry & Molecular Biology
Jose Carlos Montanes, Marta Huertas, Xavier Messeguer, M. Mar Alba
Summary: The formation of new genes can occur through gene duplication or de novo formation from noncoding sequences. Both mechanisms show similarities in terms of low sequence constraints in the initial evolutionary stages, high turnover rates at the species level, and comparable persistence rates in deeper branches. Additionally, de novo proteins tend to have an excess of substitutions between charged amino acids, leading to rapid loss of their initial highly basic character.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Multidisciplinary Sciences
Renhai Peng, Yanchao Xu, Shilin Tian, Turgay Unver, Zhen Liu, Zhongli Zhou, Xiaoyan Cai, Kunbo Wang, Yangyang Wei, Yuling Liu, Heng Wang, Guanjing Hu, Zhongren Zhang, Corrinne E. Grover, Yuqing Hou, Yuhong Wang, Pengtao Li, Tao Wang, Quanwei Lu, Yuanyuan Wang, Justin L. Conover, Hassan Ghazal, Qinglian Wang, Baohong Zhang, Marc Van Montagu, Yves Van de Peer, Jonathan F. Wendel, Fang Liu
Summary: This study obtained and assembled chromosome-scale genome sequences for two wild tetraploid cotton species (Ge and Gs) and one early domesticated species (Ghp). By conducting phylogenomic analysis, the evolutionary relationships and genomic structural variations of these cotton species were resolved. The study also identified genes associated with fiber length and environmental adaptation. These findings provide valuable insights into cotton evolution and agricultural applications.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Biotechnology & Applied Microbiology
Tarang K. Mehta, Angela Man, Adam Ciezarek, Keith Ranson, David Penman, Federica Di-Palma, Wilfried Haerty
Summary: By studying the gene expression data of Nile tilapia, we have identified highly expressed genes associated with gill adaptations. These genes show differential segregation in freshwater and euryhaline tilapia species and have functional variation at transcription factor binding sites.
Article
Agronomy
Yu Kinoshita, Ko Motoki, Munetaka Hosokawa
Summary: This study identified the candidate genes BoFLC1a and BoFLC1b as the causes of the non-flowering trait in the cabbage mutant 'nfc'. It was found that these genes were upregulated during winter in 'nfc', suggesting their involvement in the non-flowering phenotype.
THEORETICAL AND APPLIED GENETICS
(2023)
Article
Biochemistry & Molecular Biology
Wen-Biao Jiao, Vipul Patel, Jonas Klasen, Fang Liu, Petra Pecinkova, Marina Ferrand, Isabelle Gy, Christine Camilleri, Sigi Effgen, Maarten Koornneef, Ales Pecinka, Olivier Loudet, Korbinian Schneeberger
Summary: Gene duplications provide genetic backup and allow genomic changes, but may limit gene flow and cause genetic incompatibilities. Despite being observed in artificial crosses, it is unclear if these occur in nature and their impact on natural populations. This study identified genetic incompatibilities in an intercross population and found incompatible alleles in natural populations, suggesting a collective role of additional gene copies in overcoming genetic incompatibilities during population history.
MOLECULAR BIOLOGY AND EVOLUTION
(2021)