Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
出版年份 2014 全文链接
标题
Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
作者
关键词
Ovarian carcinoma, Cancer stem cell, Metastasis, Ascites, Chemoresistance, Recurrence, JAK2/STAT3 pathway
出版物
BMC CANCER
Volume 14, Issue 1, Pages -
出版商
Springer Nature
发表日期
2014-05-06
DOI
10.1186/1471-2407-14-317
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9
- (2013) Jacqueline L.Y. Chee et al. CELL CYCLE
- Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
- (2013) A. Quintas-Cardama et al. CLINICAL CANCER RESEARCH
- A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo
- (2013) D. V. Do et al. GENES & DEVELOPMENT
- Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
- (2013) Khalid Abubaker et al. Molecular Cancer
- Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules
- (2013) I. Rizvi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research
- (2013) Nuzhat Ahmed et al. Frontiers in Oncology
- ALDH1-Bright Epithelial Ovarian Cancer Cells Are Associated with CD44 Expression, Drug Resistance, and Poor Clinical Outcome
- (2012) Yu-Chi Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)
- (2012) Prabodh K Kandala et al. BMC Medicine
- Ovarian cancer stem cell markers: Prognostic and therapeutic implications
- (2012) Daniela Burgos-Ojeda et al. CANCER LETTERS
- DIMming Ovarian Cancer Growth
- (2012) Prabodh K. Kandala et al. CURRENT DRUG TARGETS
- Cancerous ovarian stem cells: Obscure targets for therapy but relevant to chemoresistance
- (2012) Nuzhat Ahmed et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies
- (2012) Pasquale Sansone et al. JOURNAL OF CLINICAL ONCOLOGY
- Gene expression analysis of matched ovarian primary tumors and peritoneal metastasis
- (2012) Joel A Malek et al. Journal of Translational Medicine
- Identification of a Potential Ovarian Cancer Stem Cell Gene Expression Profile from Advanced Stage Papillary Serous Ovarian Cancer
- (2012) Vinod Vathipadiekal et al. PLoS One
- Isolation and Characterization of Tumor Cells from the Ascites of Ovarian Cancer Patients: Molecular Phenotype of Chemoresistant Ovarian Tumors
- (2012) Ardian Latifi et al. PLoS One
- Overcoming Challenges of Ovarian Cancer Stem Cells: Novel Therapeutic Approaches
- (2012) Cristóbal Aguilar-Gallardo et al. Stem Cell Reviews and Reports
- Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance
- (2011) Ayesha B. Alvero et al. CELL CYCLE
- Absolute requirement for STAT3 function in small-intestine crypt stem cell survival
- (2011) J R Matthews et al. CELL DEATH AND DIFFERENTIATION
- Stem Cell Pathways Contribute to Clinical Chemoresistance in Ovarian Cancer
- (2011) A. D. Steg et al. CLINICAL CANCER RESEARCH
- MUC16 (CA125) regulates epithelial ovarian cancer cell growth, tumorigenesis and metastasis
- (2011) Catherine Thériault et al. GYNECOLOGIC ONCOLOGY
- Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile
- (2011) Ardian Latifi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Class III β-tubulin and the cytoskeletal gateway for drug resistance in ovarian cancer
- (2011) Marta De Donato et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The novel JAK inhibitor CYT387 suppresses multiple signalling pathways, prevents proliferation and induces apoptosis in phenotypically diverse myeloma cells
- (2011) K A Monaghan et al. LEUKEMIA
- Ovarian Cancer Development and Metastasis
- (2010) Ernst Lengyel AMERICAN JOURNAL OF PATHOLOGY
- CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms
- (2010) J. W. Tyner et al. BLOOD
- IL-4-mediated drug resistance in colon cancer stem cells
- (2010) Matilde Todaro et al. CELL CYCLE
- Epithelial Mesenchymal Transition and Cancer Stem Cell-Like Phenotypes Facilitate Chemoresistance in Recurrent Ovarian Cancer
- (2010) N. Ahmed et al. CURRENT CANCER DRUG TARGETS
- CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells
- (2010) M-Q Gao et al. ONCOGENE
- Multicellular spheroids in ovarian cancer metastases: Biology and pathology
- (2009) Kristy Shield et al. GYNECOLOGIC ONCOLOGY
- Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
- (2009) Francis Rodier et al. NATURE CELL BIOLOGY
- STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells
- (2009) Maureen M. Sherry et al. STEM CELLS
- Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas
- (2008) M Colomiere et al. BRITISH JOURNAL OF CANCER
- Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression
- (2008) Laurie G. Hudson et al. CLINICAL & EXPERIMENTAL METASTASIS
- STAT 3 as a Target for Cancer Drug Discovery
- (2008) Luca Costantino et al. CURRENT MEDICINAL CHEMISTRY
- Chemotherapeutic drugs and human tumor cells cytokine network
- (2008) Vera Levina et al. INTERNATIONAL JOURNAL OF CANCER
- Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells
- (2008) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression and activity of taxane-metobolizing enzymes in ovarian tumors
- (2007) Julie A. DeLoia et al. GYNECOLOGIC ONCOLOGY
- Expression of CD133-1 and CD133-2 in ovarian cancer
- (2007) G. FERRANDINA et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- ABCB1 G1199A Polymorphism and Ovarian Cancer Response to Paclitaxel
- (2007) Henrik Gréen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now